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Wright State University

Series

1994

Articles 1 - 6 of 6

Full-Text Articles in Life Sciences

The "Infoharness" Information Integration Platform, Leon Shklar, Satish Thatte, Howard Marcus, Amit P. Sheth Oct 1994

The "Infoharness" Information Integration Platform, Leon Shklar, Satish Thatte, Howard Marcus, Amit P. Sheth

Kno.e.sis Publications

The "InfoHarness" information integration platform, tools, and services being developed at Bellcore are aimed at providing integrated and rapid access to huge amounts of heterogeneous information independent of the type, representation, and location of information. InfoHarness provides advanced search and browsing capabilities without imposing the burden of restructuring, reformatting or relocating information on information suppliers or creators. This is achieved through object-oriented encapsulation of information and the associated meta-information (e.g., type, location, access rights, owner, creation date, etc.). The meta-information extraction methods ensure rapid and largely automatic creation of information repositories. A gateway that supports access to InfoHarness repositories from …

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Benthic-Pelagic Links: Responses Of Benthos To Water-Column Nutrient Enrichment, S. C. Blumenshine, Yvonne Vadeboncoeur, D. M. Lodge, K. L. Cottingham, S. E. Knight Sep 1994

Benthic-Pelagic Links: Responses Of Benthos To Water-Column Nutrient Enrichment, S. C. Blumenshine, Yvonne Vadeboncoeur, D. M. Lodge, K. L. Cottingham, S. E. Knight

Biological Sciences Faculty Publications

Although the responses of pelagic algae and invertebrates to gradients of nutrient enrichment are well known, less is known about the responses of benthos to such gradients or how benthic and pelagic responses may interact. We performed a 9-wk experiment in 2000-L mesocosms in the field to test for the effect of water-column nutrient enrichment on phytoplankton, algae on sediments (epipelon) and hard surfaces (plastic strips), as well as pelagic and benthic primary consumers. The experimental design consisted of 4 nutrient enrichment rates (0, 0.5, 1.0 and 2.0 μg P L-1 d-1, together with N to yield …

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Effects Of Natural Sequence Variation On Recognition By Monoclonal Antibodies Neutralize Simian Immunodeficiency Virus Infectivity, Weon Sang Choi, Catherine Collignon, Clotilde Thiriart, Dawn P. Wooley, E. J. Scott, Karen A. Kent, Ronald C. Desrosiers Sep 1994

Effects Of Natural Sequence Variation On Recognition By Monoclonal Antibodies Neutralize Simian Immunodeficiency Virus Infectivity, Weon Sang Choi, Catherine Collignon, Clotilde Thiriart, Dawn P. Wooley, E. J. Scott, Karen A. Kent, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

The determinants of immune recognition by five monoclonal antibodies (KK5, KK9, KK17, Senv7.1, and Senv101.1) that neutralize simian immunodeficiency virus infectivity were analyzed. These five neutralizing monoclonal antibodies were generated to native SIVmac251 envelope glycoprotein expressed by a vaccinia virus recombinant vector. All five recognize conformational or discontinuous epitopes and require native antigen for optimal recognition. These monoclonal antibodies also recognize SIVmac239 gp120, but they do not recognize gp120 of two natural variants of SIVmac239, 1-12 and 8-22, which evolved during the course of persistent infection in vivo (D.P.W. Burns and R.C. Desrosiers, J. Virol. 65:1843-1854, 1991). Recombinant viruses which …

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High Rates Of Frameshift Mutations Within Homo-Oligomeric Runs During A Single Cycle Of Retroviral Replication, Dawn P. Wooley, H. M. Temin Jul 1994

High Rates Of Frameshift Mutations Within Homo-Oligomeric Runs During A Single Cycle Of Retroviral Replication, Dawn P. Wooley, H. M. Temin

Neuroscience, Cell Biology & Physiology Faculty Publications

Homo-oligomeric runs were inserted into a spleen necrosis virus-based retrovirus vector to determine the nature and rate of mutations within runs of 10 to 12 identical nucleotides during a single replication cycle. Clones of helper cells containing integrated copies of retroviral vectors were used to produce virus for infection of target (nonhelper) cells. Proviral sequences from target cell clones were compared with proviral sequences from helper cell clones to study mutations that occurred during a single cycle of replication. In addition to the internal region spanning the homo-oligomeric inserts, a naturally occurring run of 10 T's in the long terminal …

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Longitudinal Dynamics Of Seston Concentration And Composition In A Lake Outlet Stream, Yvonne Vadeboncoeur Jun 1994

Longitudinal Dynamics Of Seston Concentration And Composition In A Lake Outlet Stream, Yvonne Vadeboncoeur

Biological Sciences Faculty Publications

Concentrations of suspended particulate organic carbon (POC), dissolved organic carbon, bacteria, and chlorophyll a were measured in a lake outlet in western Montana, USA. Seven sites within the first 3 km downstream from the lake were sampled over 14 mo. Downstream change in concentration of each variable was tested for fit to a power function (C=aDb). Downstream changes in POC, bacteria, and chlorophyll a, sometimes fit a power function, and the value of the exponent b was positively correlated with discharge. At low discharge, a downstream decline in lake algae was accompanied by an increase in stream algae. …

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Using Tickets To Enforce The Serializability Of Multidatabase Transactions, Dimitrios Georgakopoulos, Marek Rusinkiewicz, Amit P. Sheth Feb 1994

Using Tickets To Enforce The Serializability Of Multidatabase Transactions, Dimitrios Georgakopoulos, Marek Rusinkiewicz, Amit P. Sheth

Kno.e.sis Publications

To enforce global serializability in a multidatabase environment the multidatabase transaction manager must take into account the indirect (transitive) conflicts between multidatabase transactions caused by local transactions. Such conflicts are difficult to resolve because the behavior or even the existence of local transactions is not known to the multidatabase system. To overcome these difficulties, we propose to incorporate additional data manipulation operations in the subtransactions of each multidatabase transaction. We show that if these operations create direct conflicts between subtransactions at each participating local database system, indirect conflicts can be resolved even if the multidatabase system is not aware of …

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