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Immunology and Infectious Disease

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Full-Text Articles in Life Sciences

Environmental Ecology And Life History Variation Of Perkinsus Marinus, Lydia M. Bienlien Jan 2022

Environmental Ecology And Life History Variation Of Perkinsus Marinus, Lydia M. Bienlien

Dissertations, Theses, and Masters Projects

Marine resources provide a growing world population with the opportunity to increase food security, particularly through aquaculture. Oysters are prominent aquacultured species, but marine diseases are a threat to the growth and sustainability of oyster culture. Perkinsus marinus is the most important oyster pathogen of the Atlantic and Gulf coasts of the U.S., where it causes substantial mortality. Despite being one of the most well-studied protozoan parasites of bivalve molluscs, much is still unknown about P. marinus. This research investigated multiple characteristics of P. marinus.In Chapter Two, the environmental ecology of P. marinus was explored through tidal sampling and year-long …


Evaluation Of The Safety And Efficacy Of Hand Sanitizer Products Marketed To Children Available During The Covid-19 Pandemic, L.E. Gloekler, E.J. De Gandiaga, N.R. Binczewski, (...), Mark J. La Guardia, Et Al Jan 2022

Evaluation Of The Safety And Efficacy Of Hand Sanitizer Products Marketed To Children Available During The Covid-19 Pandemic, L.E. Gloekler, E.J. De Gandiaga, N.R. Binczewski, (...), Mark J. La Guardia, Et Al

VIMS Articles

Hand sanitizer use in the United States (U.S.) increased after the SARS-CoV-2 outbreak. The U.S. Food and Drug Administration (FDA) released temporary manufacturer guidance, changing impurity level limits for alcohol-based hand sanitizers (ABHSs). Since the guidance took effect, the FDA has recommended against using these hand sanitizers due to concerns over safety, efficacy, and/or risk of incidental ingestion. To address current gaps in exposure characterization, this study describes a survey of ABHSs marketed to children available in the U.S., as defined by several inclusion criteria. A subset of ABHSs (n = 31) were evaluated for ethanol and organic impurities using …


The Importance Of Long-Term Data Collection To Understand The Historical And Evolutionary Ecology Of Marine Diseases: The Eastern Oyster Disease System In The Usa, As A Case Study, Ryan Carnegie Jan 2021

The Importance Of Long-Term Data Collection To Understand The Historical And Evolutionary Ecology Of Marine Diseases: The Eastern Oyster Disease System In The Usa, As A Case Study, Ryan Carnegie

VIMS Articles

The epizootics in eastern oysters, Crassostrea virginica, of haplosporidiosis or “MSX” disease caused by Haplosporidium nelsoni, and perkinsosis or “dermo” disease caused by Perkinsus marinus, were two of the most significant marine disease events of the last century. Haplosporidium nelsoni, a protozoan parasite
native to Asian populations of the Pacific oyster Crassostrea gigas, emerged in Delaware Bay in 1957 and Chesapeake Bay in 1959 (Andrews,1962; Haskin et al., 1966), and in the decades that followed caused major mortality events
from the Mid-Atlantic region of the USA to Atlantic Canada. Perkinsus marinus is a native pathogen, also a protozoan, that had …


Polystyrene Microplastics Reduce Abundance Of Developing B Cells In Rainbow Trout (Oncorhynchus Mykiss) Primary Cultures, Patty Zwollo, Fatima Quddos, Carey Bagdassarian, Meredith Evans Seeley, Robert Hale, Lauren Abderhalden Jan 2021

Polystyrene Microplastics Reduce Abundance Of Developing B Cells In Rainbow Trout (Oncorhynchus Mykiss) Primary Cultures, Patty Zwollo, Fatima Quddos, Carey Bagdassarian, Meredith Evans Seeley, Robert Hale, Lauren Abderhalden

VIMS Articles

Environmental microplastic pollution (including polystyrene, PS) may have detrimental effects on the health of aquatic organisms. Accumulation of PS microplastics has been reported to affect innate immune cells and inflammatory responses in fish. To date, knowledge on effects of microplastics on the antibody response is still very limited. Here, we investigated effects of small (0.8–20 μm) PS microplastics on the abundance of B lineage cells in primary cultures of developing immune cells from the anterior kidney of rainbow trout. Both purchased PS microbeads and PS microparticles generated from consumer products were used as microplastic sources. We first show that rainbow …


First Comparison Of French And Australian Oshv-1 Μvars By Bath Exposure, Ca Burge, Kimberly S. Reece, Ak Dhar, P Kirkland, B Morga, L Dégremont, N Faury, B Whipple, A Macintyre, C Friedman Jan 2020

First Comparison Of French And Australian Oshv-1 Μvars By Bath Exposure, Ca Burge, Kimberly S. Reece, Ak Dhar, P Kirkland, B Morga, L Dégremont, N Faury, B Whipple, A Macintyre, C Friedman

VIMS Articles

Economically devastating mortality events of farmed and wild shellfish due to infectious disease have been reported globally. Currently, one of the most significant disease threats to Pacific oyster Crassostrea gigas culture is the ostreid herpesvirus 1 (OsHV-1), in particular the emerging OsHV-1 microvariant genotypes. OsHV-1 microvariants (OsHV-1 μvars) are spreading globally, and concern is high among growers in areas unaffected by OsHV-1. No study to date has compared the relative virulence among variants. We provide the first challenge study comparing survival of naïve juvenile Pacific oysters exposed to OsHV-1 μvars from Australia (AUS μvar) and France (FRA μvar). Oysters challenged …


The Effect Of Slow Release Cortisol Implant On Humoral Immune Responses And Infection Prevalence Following Experimental Challenge With Flavobacterium Psycrophilum In Rainbow Trout (Oncorhynchus Mykiss), Fatima Quddos Jan 2020

The Effect Of Slow Release Cortisol Implant On Humoral Immune Responses And Infection Prevalence Following Experimental Challenge With Flavobacterium Psycrophilum In Rainbow Trout (Oncorhynchus Mykiss), Fatima Quddos

Dissertations, Theses, and Masters Projects

Pacific salmon migrate long distances to spawn as part of their life cycle. During this journey from sea to their natal stream, they undergo major endocrine, physiological and immune changes. Cortisol, the primary stress hormone, gradually increases during the journey. Persistent high cortisol levels have deleterious health effects, including suppression of the antibody response. However, pathogens encountered during their journey may stimulate antibody responses to overcome the infection. My main research question focuses on how salmonids balance the immunosuppressive effects of high cortisol levels with activation of the antibody response. A recent field study from our lab showed a transient …


Characterization Of Microsporidian Ameson Herrnkindi Sp. Nov. Infecting Caribbean Spiny Lobsters Panulirus Argus, Hamish J. Small, Gd Stentiford, Dc Behringer, Ma Freeman, Nam Atherley, Kimberly S. Reece, Jeffrey D. Shields Oct 2019

Characterization Of Microsporidian Ameson Herrnkindi Sp. Nov. Infecting Caribbean Spiny Lobsters Panulirus Argus, Hamish J. Small, Gd Stentiford, Dc Behringer, Ma Freeman, Nam Atherley, Kimberly S. Reece, Jeffrey D. Shields

VIMS Articles

The Caribbean spiny lobster Panulirus argus supports a large and valuable fishery in the Caribbean Sea. In 2007-2008, a rare microsporidian parasite with spore characteristics typical of the Ameson genus was detected in 2 spiny lobsters from southeast Florida (FL). However, the parasite species was not confirmed by molecular analyses. To address this deficiency, reported here are structural and molecular data on single lobsters displaying comparable ‘cotton-like’ abdominal muscle containing ovoid microsporidian spores found at different locations in FL in 2014 and 2018 and in Saint Kitts and Nevis Islands in 2017. In the lobster from 2014, multiple life stages …


Parasitic Dinoflagellate Hematodinium Perezi Prevalence In Larval And Juvenile Blue Crabs Callinectes Sapidus From Coastal Bays Of Virginia, Hj Small, Jp Huchin-Mian, Ks Reece, Km Pagenkopp Lohan, Mj Butler Iv, Jd Shields Jun 2019

Parasitic Dinoflagellate Hematodinium Perezi Prevalence In Larval And Juvenile Blue Crabs Callinectes Sapidus From Coastal Bays Of Virginia, Hj Small, Jp Huchin-Mian, Ks Reece, Km Pagenkopp Lohan, Mj Butler Iv, Jd Shields

VIMS Articles

The parasitic dinoflagellate Hematodinium perezi infects the American blue crab Callinectes sapidus and other decapods along the Eastern seaboard and Gulf of Mexico coast of the USA. Large juvenile and adult blue crabs experience high mortality during seasonal outbreaks of H. perezi, but less is known about its presence in the early life history stages of this host. We determined the prevalence of H. perezi in megalopae and early benthic juvenile crabs from multiple locations along the Virginia portion of the Delmarva Peninsula. The DNA of H. perezi was not detected in any megalopae collected from several locations within the …


Method For Serial Passage Of Infectious Hematopoietic Necrosis Virus (Ihnv) In Rainbow Trout, Juliette Doumayrou, M. Gray Ryan, Andrew R. Wargo Jan 2019

Method For Serial Passage Of Infectious Hematopoietic Necrosis Virus (Ihnv) In Rainbow Trout, Juliette Doumayrou, M. Gray Ryan, Andrew R. Wargo

VIMS Articles

Transmission is a fundamental component of pathogen fitness. A better understanding of pathogen transmission can greatly improve disease management. In particular, controlled studies of multiple rounds of natural transmission (i.e. serial passage) can provide powerful epidemiological and evolutionary inferences. However, such studies are possible in only a few systems because of the challenges in successfully initiating and maintaining transmission in the laboratory. Here we developed an efficient and reproducible cohabitation method for conducting controlled experiments investigating the effects of serial passage on infectious hematopoietic necrosis virus (IHNV) in rainbow trout. This method was used to investigate the transmission efficiency and …


Rising Temperatures, Molting Phenology, And Epizootic Shell Disease In The American Lobster, Maya Groner, Jeffrey D. Shields, Df Landers, J Swenarton, Jm Hoenig Nov 2018

Rising Temperatures, Molting Phenology, And Epizootic Shell Disease In The American Lobster, Maya Groner, Jeffrey D. Shields, Df Landers, J Swenarton, Jm Hoenig

VIMS Articles

Phenological mismatchmaladaptive changes in phenology resulting from altered timing of environmental cuesis an increasing concern in many ecological systems, yet its effects on disease are poorly characterized. American lobster (Homarus americanus) is declining at its southern geographic limit. Rising seawater temperatures are associated with seasonal outbreaks of epizootic shell disease (ESD), which peaks in prevalence in the fall. We used a 34-year mark-recapture data set to investigate relationships between temperature, molting phenology, and ESD in Long Island Sound, where temperatures are increasing at 0.4 degrees C per decade. Our analyses support the hypothesis that phenological mismatch is linked to the …


Laboratory Studies On The Effect Of Temperature On Epizootic Shell Disease In The American Lobster, Homarus Americanus, Britnee N. Barris, Jeffrey D. Shields, Hamish J. Small, Juan Pablo Huchin-Mian, Patricia O'Leary, Et Al Jul 2018

Laboratory Studies On The Effect Of Temperature On Epizootic Shell Disease In The American Lobster, Homarus Americanus, Britnee N. Barris, Jeffrey D. Shields, Hamish J. Small, Juan Pablo Huchin-Mian, Patricia O'Leary, Et Al

VIMS Articles

Epizootic shell disease (ESD) is a persistent threat to the population of American lobsters, Homarus americanus H. Milne-Edwards, 1837, in Long Island Sound and off southern New England, USA. ESD is caused by a bacterial dysbiosis that occurs in association with increased water temperature and exposure to anthropogenic stressors. Temperature is a leading factor driving the severity and incidence of ESD. Our objective was to quantify disease progression and dynamics in relation to host molting and mortality at three rigorously controlled temperatures (6, 12, and 18 °C) over a 5–6-mo period. Lobsters were photographed at various time points and image …


The Development Of Fiddler Crabs (Uca Spp.) As A Comparative Model System For The Parasitic Dinoflagellate, Hematodinium Perezi And Its Natural Host The Blue Crab, Callinectes Sapidus, Patricia Anne O'Leary Jan 2018

The Development Of Fiddler Crabs (Uca Spp.) As A Comparative Model System For The Parasitic Dinoflagellate, Hematodinium Perezi And Its Natural Host The Blue Crab, Callinectes Sapidus, Patricia Anne O'Leary

Dissertations, Theses, and Masters Projects

Herein, I have completed several experiments which encompass developing fiddler crabs as a model system, as well as sentinel and temperature studies to investigate biotic and abiotic factors in parasite transmission. My studies show which factors prevent, delay, or accelerate transmission and progression of H. perezi. The fiddler crab experiments by chapter are as follows: Chapter 1. I screened adult and juvenile fiddler crab populations for naturally occurring H. perezi infections at endemic and non-endemic sites. No natural infections were found in the adult or juvenile populations (Chapter 1 and 3). I completed inoculation trials with U. minax, U. pugnax, …


Reproductive Investment In Crassostrea Virginica As An Indicator Of A Tolerance Response To Perkinsus Marinus, Lauren Irene Huey Jan 2018

Reproductive Investment In Crassostrea Virginica As An Indicator Of A Tolerance Response To Perkinsus Marinus, Lauren Irene Huey

Dissertations, Theses, and Masters Projects

The Chesapeake Bay region values oysters for the ecosystem services, lucrative fishery, and historical significance that the species embodies; however, over the last half century, oyster abundances have been reduced to historical lows. Two protozoan parasites, Perkinsus marinus and Haplosporidium nelsoni, have been major influences on oyster populations, especially in high-salinity regions. Today, the population is recovering; catches have increased and oysters have expanded spatially. to investigate the cause of the recovery, three measurements were made on slides of oysters from a histological archive collected during summer at Wreck Shoal in the James River from 1988–2017: oocyte diameter, oocyte density, …


Bottom-Up Control Of Parasites, David S. Johnson, Richard Heard Oct 2017

Bottom-Up Control Of Parasites, David S. Johnson, Richard Heard

VIMS Articles

Parasitism is a fundamental ecological interaction. Yet we understand relatively little about the ecological role of parasites compared to the role of free-living organisms. Bottom-up theory predicts that resource enhancement will increase the abundance and biomass of free-living organisms. Similarly, parasite abundance and biomass should increase in an ecosystem with resource enhancement. We tested this hypothesis in a landscape-level experiment in which salt marshes (60,000 m2 each) received elevated nutrient concentrations via flooding tidal waters for 11 yr to mimic eutrophication. Nutrient enrichment elevated the densities of the talitrid amphipod, Orchestia grillus, and the density and biomass of its …


Impact Of The Parasitic Nematode Anguillicoloides Crassus On American Eels (Anguilla Rostrata) In Chesapeake Bay, Zoemma Taudel Warshafsky Jan 2017

Impact Of The Parasitic Nematode Anguillicoloides Crassus On American Eels (Anguilla Rostrata) In Chesapeake Bay, Zoemma Taudel Warshafsky

Dissertations, Theses, and Masters Projects

American eels are infected by the introduced parasitic nematode, Anguillicoloides crassus, which can cause significant damage to their swimbladders. Despite the high prevalence and severe damage caused by A. crassus, the population level effects on American eels are not well understood. The prevalence and swimbladder damage in young glass eels and elvers are relatively unstudied, despite the potential for this parasite to cause tissue damage. Additionally, the effects of environmental, temporal, and spatial variables have been debated in previous studies without consensus. Also, the potential for eels to recover from infection and tissue damage has been speculated but not definitively …


Transmission Routes Maintaining A Viral Pathogen Of Steelhead Trout Within A Complex Multi-Host Assemblage, Rachel Breyta, Ilana Brito, Paige Ferguson, Gael Kurath, Kerry Naish, Maureen Purcell, Ar Wargo, Shannon Ladeau Jan 2017

Transmission Routes Maintaining A Viral Pathogen Of Steelhead Trout Within A Complex Multi-Host Assemblage, Rachel Breyta, Ilana Brito, Paige Ferguson, Gael Kurath, Kerry Naish, Maureen Purcell, Ar Wargo, Shannon Ladeau

VIMS Articles

This is the first comprehensive region wide, spatially explicit epidemiologic analysis of surveillance data of the aquatic viral pathogen infectious hematopoietic necrosis virus (IHNV) infecting native salmonid fish. The pathogen has been documented in the freshwater ecosystem of the Pacific Northwest of North America since the 1950s, and the current report describes the disease ecology of IHNV during 2000-2012. Prevalence of IHNV infection in monitored salmonid host cohorts ranged from 8% to 30%, with the highest levels observed in juvenile steelhead trout. The spatial distribution of all IHNV-infected cohorts was concentrated in two sub-regions of the study area, where historic …


Influence Of Perkinsus Marinus Infection And Oyster Health On Levels Of Human-Pathogenic Vibrios In Oysters, Lydia M. Bienlien Jan 2016

Influence Of Perkinsus Marinus Infection And Oyster Health On Levels Of Human-Pathogenic Vibrios In Oysters, Lydia M. Bienlien

Dissertations, Theses, and Masters Projects

The eastern oyster Crassostrea virginica is an ecologically and commercially important species whose natural populations have been devastated by overharvesting, habitat destruction, and disease, but the rapid growth of oyster aquaculture has shown potential to restore the economic significance of this species. A key threat to the growth and sustainability of oyster aquaculture is the association of human-pathogenic Vibrio bacteria with product marketed for raw consumption. Two Vibrio species, Vibrio vulnificus and Vibrio parahaemolyticus, are the causes of the highest rates of seafood consumption-related mortality and gastrointestinal illness, respectively. Identification of the factors influencing V. vulnificus and V. parahaemolyticus prevalence …


Impact Of Anguillicolides Crassus On American Eels (Anguilla Rostrata), Andrew Wargo, Rob Latour, Troy D. Tuckey, Wolfgang K. Vogelbein Oct 2015

Impact Of Anguillicolides Crassus On American Eels (Anguilla Rostrata), Andrew Wargo, Rob Latour, Troy D. Tuckey, Wolfgang K. Vogelbein

Presentations

American eels Anguilla rostrata are infected by an introduced parasitic nematode Anguillicoloides crassus, which can cause extreme necrosis of their swimbladders, yet effects on the eel population are currently unknown. We collected 3 eel life stages (glass, elver, and yellow) and the presence of A. crassus and swimbladder damage in each eel was quantified. The preliminary data show over 60% prevalence and an even higher prevalence of damaged swimbladders.


A Novel Test Of The Immunocompetence Handicap Hypothesis, Jessica H. Ebers Jan 2014

A Novel Test Of The Immunocompetence Handicap Hypothesis, Jessica H. Ebers

Dissertations, Theses, and Masters Projects

No abstract provided.


The Role Of Mycobacteriosis In Elevated Natural Mortality Of Chesapeake Bay Striped Bass: Developing Better Models For Stock Assessment And Management : A Final Report, Wolfgang K. Vogelbein, John Hoenig, David Gauthier, Matthew Smith, Phil Sadler, Howard Kator, Martha Rhodes Aug 2012

The Role Of Mycobacteriosis In Elevated Natural Mortality Of Chesapeake Bay Striped Bass: Developing Better Models For Stock Assessment And Management : A Final Report, Wolfgang K. Vogelbein, John Hoenig, David Gauthier, Matthew Smith, Phil Sadler, Howard Kator, Martha Rhodes

Reports

Mycobacteriosis is a chronic systemic disease of fishes caused by bacteria belonging to the genus Mycobacterium. The disease currently affects striped bass throughout Chesapeake Bay and prevalence is higher than 90% in certain age groups. Two recently described species, M. shottsii and M. pseudoshottsii, are the most common isolates obtained from diseased fish and are considered the primary etiologic agents. Recent indications that natural mortality (M) has become elevated in Chesapeake Bay striped bass and that mycobacteriosis may be the underlying cause, has caused concern among fishermen, fisheries managers and scientists. However, fundamental questions, such as transmission mode, duration of …


Sublethal Effects Of Methylmercury On The Songbird Immune Response: An Experimental Study, Catherine Ann Lewis Jan 2012

Sublethal Effects Of Methylmercury On The Songbird Immune Response: An Experimental Study, Catherine Ann Lewis

Dissertations, Theses, and Masters Projects

No abstract provided.


Molecular Genetic Studies Of Hematodinium Sp., A Parasitic Dinoflagellate Of The Blue Crab, Callinectes Sapidus, Katrina M. Pagenkopp Lohan Jan 2011

Molecular Genetic Studies Of Hematodinium Sp., A Parasitic Dinoflagellate Of The Blue Crab, Callinectes Sapidus, Katrina M. Pagenkopp Lohan

Dissertations, Theses, and Masters Projects

Economically viable fisheries for the American blue crab, Callinectes sapidus, occur in the USA from Delaware Bay to the Gulf of Mexico. Unfortunately, a number of factors, including overexploitation, degraded habitats, and disease, have contributed to the decline of blue crab populations in the USA. In April 2008, the Secretary of Commerce declared the blue crab fishery in the Chesapeake Bay a "commercial fishery disaster." One factor potentially contributing to the decline of blue crab populations in high salinity waters is infection with Hematodinium sp., a parasitic dinoflagellate, which can cause significant mortalities in blue crab populations. Since the first …


The Development And Application Of An Antibody-Based Biosensor For The Detection Of The Petroleum-Derived Compounds, Candace Rae Spier Jan 2011

The Development And Application Of An Antibody-Based Biosensor For The Detection Of The Petroleum-Derived Compounds, Candace Rae Spier

Dissertations, Theses, and Masters Projects

Petroleum is one of the most important natural resources, but can also be problematic to environmental and human health. Petroleum is comprised of thousands of compounds, including polycyclic aromatic hydrocarbons (PAHs) and heterocycles, some of which are toxic and/or carcinogenic. Traditional analytical methods for environmental monitoring of low-level PAHs are time-consuming labor-intensive, and often laboratory-bound. Efforts to achieve timely, sensitive, and accurate analysis of PAHs in the field have become a priority for environmental research and monitoring. Antibody-based biosensors are presently being developed for environmental analysis. Anti-PAH antibody molecules can be coupled with electronic transducers to provide new biosensor technology …


Status Of The Major Oyster Diseases In Virginia 2006-2008 A Summary Of The Annual Oyster Disease Monitoring Program, Ryan Carnegie, Eugene M. Burreson Dec 2009

Status Of The Major Oyster Diseases In Virginia 2006-2008 A Summary Of The Annual Oyster Disease Monitoring Program, Ryan Carnegie, Eugene M. Burreson

Reports

Fall Survey sampling revealed P. marinus levels to be generally normal to high in Virginia tributaries. By 2007 P. marinus was present on every oyster reef sampled, and by the end of the 2006-2008 period the parasite was probably causing some mortality throughout Virginia waters. Data for H. nelsoni are still incomplete for 2006/7 because of funding limitations, but in 2008 H. nelsoni was observed at 17 of 31 sampled reefs, a marked expansion in distribution since 2003/4. A significant MSX disease outbreak occurred in the Great Wicomico River in 2008, as a mild winter and a long period of …


Characterization Of A Rediscovered Haplosporidian Parasite From Cultured Penaeus Vannamei, Lm Nunam, Dv Lightner, Cr Pantoja, Na Stokes, Kimberly S. Reece Feb 2007

Characterization Of A Rediscovered Haplosporidian Parasite From Cultured Penaeus Vannamei, Lm Nunam, Dv Lightner, Cr Pantoja, Na Stokes, Kimberly S. Reece

VIMS Articles

Mortalities of Penaeus vannamei, cultured in ponds in Belize, Central America, began during the last part of the grow-out cycle during the cold weather months from September 2004 through February 2005. Tissue squashes of infected hepatopancreata and histological examination of infected shrimp revealed that the mortalities might have been caused by an endoparasite. To confirm the diagnosis, DNA was extracted from ethanol preserved hepatopancreata and the small-subunit rRNA gene was sequenced. The 1838 by sequence was novel and phylogenetic analysis placed the P. vannamei parasite within the phylum Haplosporidia as a sister taxon to a clade that includes Bonamia and …


Globally Distributed Mycobacterial Fish Pathogens Produce A Novel Plasmid-Encoded Toxic Macrolide, Mycolactone F, B S. Ranger, E A. Malone, L Mosi, S Adusumilli, R E. Lee, A Coloni, M Rhodes, Plc Small Nov 2006

Globally Distributed Mycobacterial Fish Pathogens Produce A Novel Plasmid-Encoded Toxic Macrolide, Mycolactone F, B S. Ranger, E A. Malone, L Mosi, S Adusumilli, R E. Lee, A Coloni, M Rhodes, Plc Small

VIMS Articles

Mycobacterium ulcerans and Mycobacterium marinum are closely related pathogens which share an aquatic environment. The pathogenesis of these organisms in humans is limited by their inability to grow above 35 degrees C. M. marinum causes systemic disease in fish but produces localized skin infections in humans. M. ulcerans causes Burulli ulcer, a severe human skin lesion. At the molecular level, M. ulcerans is distinguished from M. marinum by the presence of a virulence plasmid which encodes a macrolide toxin, mycolactone, as well as by hundreds of insertion sequences, particularly IS2404. There has been a global increase in reports of fish …


Status Of The Major Oyster Diseases In Virginia 2005 A Summary Of The Annual Monitoring Program, Ryan Carnegie, Eugene M. Burreson Jul 2006

Status Of The Major Oyster Diseases In Virginia 2005 A Summary Of The Annual Monitoring Program, Ryan Carnegie, Eugene M. Burreson

Reports

More normal riverflows and salinities returned in 2005 after two very wet years. Temperatures were somewhat colder than normal during the winter, and warmer during the summer. The physical environment was generally more favorable for parasite activity, and thus brought a slight increase in prevalence and intensity of the oyster diseases caused by Perkinsus marinus (Dermo) and Haplosporidium nelsoni (MSX). Among quarterly James River Survey sites, maximum annual P. marinus prevalences returned to levels typical of the mid- 1990s, before the years of drought. P. marinus prevalence reached 92% at Wreck Shoal, 56% at Point of Shoal, 68% at Horsehead …


Mycobacterial Infections In Striped Bass (Morone Saxatilis) From Delaware Bay, Christopher A. Ottinger, J. Jed Brown, Et Al, Martha Rhodes, Howard Kator, David T. Gauthier, Wolfgang K. Vogelbein Jan 2006

Mycobacterial Infections In Striped Bass (Morone Saxatilis) From Delaware Bay, Christopher A. Ottinger, J. Jed Brown, Et Al, Martha Rhodes, Howard Kator, David T. Gauthier, Wolfgang K. Vogelbein

VIMS Books and Book Chapters

Much of what is known of mycobacteriosis in wild striped bass from the mid-Atlantic region of the United States is based on our observations from Chesapeake Bay and its tributaries, where high infection prevalence and lesioned fish are frequently observed. Comparatively, the occurrence and severity of mycobacteriosis in striped bass from watersheds adjacent to Chesapeake Bay are relatively unknown. This study represents the first report on mycobacterial infection in striped bass harvested from two sites in Delaware Bay.


Epizootic Mycobacteriosis In Chesapeake Bay Striped Bass: What Is The Fate Of Infected Fish?, Wolfgang K. Vogelbein, John M. Hoenig, David T. Gauthier Jan 2006

Epizootic Mycobacteriosis In Chesapeake Bay Striped Bass: What Is The Fate Of Infected Fish?, Wolfgang K. Vogelbein, John M. Hoenig, David T. Gauthier

VIMS Books and Book Chapters

Striped bass (Morone saxatilis) in Chesapeake Bay, USA, are currently experiencing an epizootic of mycobacteriosis. Visceral disease prevalence in resident fish exceeds 50% and prevalence of skin ulcers can exceed 30% in some areas. Two primary hypotheses regarding emergence of this chronic bacterial disease propose that anthropogenic stressors constitute important underlying modulating factors


The Ecology Of Mycobacteria Infecting Striped Bass (Morone Saxatilis) In Chesapeake Bay: A Research Plan, Howard Kator, Martha Rhodes, David Gauthier Jan 2006

The Ecology Of Mycobacteria Infecting Striped Bass (Morone Saxatilis) In Chesapeake Bay: A Research Plan, Howard Kator, Martha Rhodes, David Gauthier

VIMS Books and Book Chapters

The ecology of mycobacteria in estuarine and marine waters remains poorly understood. The current epizootic in Chesapeake Bay striped bass and newly described pathogens Mycobacterium shottsii and M. pseudoshottsii raise ecological questions that if answered can improve our understanding of the pathogenesis of mycobacteriosis in this fish species.