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Full-Text Articles in Life Sciences
Quantifying Limits On Replication, Death, And Quiescence Of Mycobacterium Tuberculosis In Mice, Margaret M. Mcdaniel, Nitin Krishna, Winode G. Handagama, Shigetoshi Eda, Vitaly V. Ganusov
Quantifying Limits On Replication, Death, And Quiescence Of Mycobacterium Tuberculosis In Mice, Margaret M. Mcdaniel, Nitin Krishna, Winode G. Handagama, Shigetoshi Eda, Vitaly V. Ganusov
Microbiology Publications and Other Works
When an individual is exposed to Mycobacterium tuberculosis (Mtb) three outcomes are possible: bacterial clearance, active disease, or latent infection. It is generally believed that most individuals exposed to Mtb become latently infected and carry the mycobacteria for life. How Mtb is maintained during this latent infection remains largely unknown. During an Mtb infection in mice, there is a phase of rapid increase in bacterial numbers in the murine lungs within the first 3 weeks, and then bacterial numbers either stabilize or increase slowly over the period of many months. It has been debated whether the relatively constant numbers of …
Evidence For The Priming Effect In A Planktonic Estuarine Microbial Community, Andrew D. Steen, Lauren N.M. Quigley, Alison Buchan
Evidence For The Priming Effect In A Planktonic Estuarine Microbial Community, Andrew D. Steen, Lauren N.M. Quigley, Alison Buchan
Microbiology Publications and Other Works
The “priming effect,” in which addition of labile substances changes the remineralization rate of recalcitrant organic matter, has been intensively studied in soils, but is less well-documented in aquatic systems. We investigated the extent to which additions of nutrients or labile organic carbon could influence remineralization rates of 14C-labeled, microbially-degraded, phytoplankton-derived organic matter (OM) in microcosms inoculated with microbial communities drawn from Grove Creek Estuary in coastal Georgia, USA. We found that amendment with labile protein plus phosphorus increased remineralization rates of degraded, phytoplankton-derived OM by up to 100%, whereas acetate slightly decreased remineralization rates relative to an unamended control. …