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Effects Of Long-Term Hypoxia On Enzymes Of Carbohydrate Metabolism In The Gulf Killifish, Fundulus Grandis, Bernard Rees Oct 2006

Effects Of Long-Term Hypoxia On Enzymes Of Carbohydrate Metabolism In The Gulf Killifish, Fundulus Grandis, Bernard Rees

Biological Sciences Faculty Publications

The goal of the current study was to generate a comprehensive, multi-tissue perspective of the effects of chronic hypoxic exposure on carbohydrate metabolism in the Gulf killifish Fundulus grandis. Fish were held at approximately 1.3 mg l(-1) dissolved oxygen (approximately 3.6 kPa) for 4 weeks, after which maximal activities were measured for all glycolytic enzymes in four tissues (white skeletal muscle, liver, heart and brain), as well as for enzymes of glycogen metabolism (in muscle and liver) and gluconeogenesis (in liver). The specific activities of enzymes of glycolysis and glycogen metabolism were strongly suppressed by hypoxia in white skeletal muscle, …


Effects Of Long-Term Hypoxia On Enzymes Of Carbohydrate Metabolism In The Gulf Killifish, Fundulus Grandis, M L. Manning, C A. Landry, R D. Boehm, S Manning, A O. Cheek, Bernard B. Rees Jan 2006

Effects Of Long-Term Hypoxia On Enzymes Of Carbohydrate Metabolism In The Gulf Killifish, Fundulus Grandis, M L. Manning, C A. Landry, R D. Boehm, S Manning, A O. Cheek, Bernard B. Rees

Biological Sciences Faculty Publications

The goal of the current study was to generate a comprehensive, multi-tissue perspective of the effects of chronic hypoxic exposure on carbohydrate metabolism in the Gulf killifish Fundulus grandis. Fish were held at approximately 1.3·mg·l–1 dissolved oxygen (~3.6·kPa) for 4·weeks, after which maximal activities were measured for all glycolytic enzymes in four tissues (white skeletal muscle, liver, heart and brain), as well as for enzymes of glycogen metabolism (in muscle and liver) and gluconeogenesis (in liver). The specific activities of enzymes of glycolysis and glycogen metabolism were strongly suppressed by hypoxia in white skeletal muscle, which may reflect decreased energy …


Structure And Sequence Conservation Of A Putative Hypoxia Responsive Element In The Lactate Dehydrogenase-B Gene Of Fundulus, Bernard B. Rees, John A.L. Bowman, P M. Schulte Jan 2006

Structure And Sequence Conservation Of A Putative Hypoxia Responsive Element In The Lactate Dehydrogenase-B Gene Of Fundulus, Bernard B. Rees, John A.L. Bowman, P M. Schulte

Biological Sciences Faculty Publications

No abstract provided.