Life Sciences Commons^™

Sarcopenia And The Importance Of Resistance Training And Protein-Rich Diets For Prevention Of Muscle Loss In Older Adults: A Literature Review And Informational Pamphlet, Madison Steele

Honors Theses

The growing prevalence of sarcopenia among older adults as well as youths has prompted further research aimed at developing effective preventative measures and treatment plans. Sarcopenia is often thought to occur solely due to aging, but several other factors contribute to progressive muscle loss. Previous research studies have found an effect of physical activity and dietary protein levels on the risk of developing sarcopenia as well as its onset age. This study aims to review existing knowledge in the field to compile an extensive list of sarcopenia causes and methods of prevention. The main causes identified in this review are …

Profile Of Producers And Production Of Dry-Aged Beef In Brazil, Jonatã Henrique Rezende-De-Souza, Flavio Andre Bolini Cardello, Ana Paula Moraes De Paula, Felipe A. Ribeiro, Chase C. Calkins, Sérgio Bertelli Pflanzer

Department of Animal Science: Faculty Publications

No information is currently available on the profile of producers and production process of dry-aged beef in Brazil, to the best of the authors’ knowledge. We surveyed 37 Brazilian companies that were producing dry-aged beef in 2020 to investigate this market. The absolute and relative frequency of responses was calculated to obtain the sum, average, minimum, and maximum values. From the respondents, dry-aged beef was first produced in 2009, and most producers are located in big cities. Most respondents control and monitor chamber temperature; however, humidity and air velocity only are monitored. The aging period (mostly between 22 to 60 …

Sestrins: Emerging Dynamic Stress-Sensors In Metabolic And Environmental Health, Seung Hyun Ro, Julianne Fay, Cesar I. Cyuzuzo, Yura Jang, Naeun Lee, Hyun Seob Song, Edward N. Harris

Department of Biochemistry: Faculty Publications

Proper timely management of various external and internal stresses is critical for metabolic and redox homeostasis in mammals. In particular, dysregulation of mechanistic target of rapamycin complex (mTORC) triggered from metabolic stress and accumulation of reactive oxygen species (ROS) generated from environmental and genotoxic stress are well-known culprits leading to chronic metabolic disease conditions in humans. Sestrins are one of the metabolic and environmental stress-responsive groups of proteins, which solely have the ability to regulate both mTORC activity and ROS levels in cells, tissues and organs. While Sestrins are originally reported as one of several p53 target genes, recent studies …

Systematic Age-, Organ-, And Diet-Associated Ionome Remodeling And The Development Of Ionomic Aging Clocks, Bohan Zhang, Dmitriy I. Podolskiy, Marco Mariotti, Javier Seravalli, Vadim N. Gladyshev

Department of Biochemistry: Faculty Publications

Aging involves coordinated yet distinct changes in organs and systems throughout life, including changes in essential trace elements. However, how aging affects tissue element composition (ionome) and how these changes lead to dysfunction and dis-ease remain unclear. Here, we quantified changes in the ionome across eight organs and 16 age groups of mice. This global profiling revealed novel interactions between elements at the level of tissue, age, and diet, and allowed us to achieve a broader, organismal view of the aging process. We found that while the entire ionome stead-ily transitions along the young-to-old trajectory, individual organs are characterized by …

Exit Here: Strategies For Dealing With Aging Dams And Reservoirs, Henry H. Hansen, Emily Forzono, Alisha Grams, Lindsay Ohlman, Christine Ruskamp, Mark A. Pegg, Kevin L. Pope

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Aging infrastructure is prevalent throughout the world, but water control management structures, specifically dams, are of growing concern. Dams and their corresponding reservoirs have inherent, but separate, lifespans. The proportion of dams around the world that continue operation beyond their intended lifespans is growing at an alarming rate. Society will not only have to navigate the tradeoffs associated with the deterioration of services provided by reservoirs and dams, but also impending structural failures. Society is nearing a critical pinch point where we will have to decide how to deal with dams and reservoirs at scales that range from a single …

Reliability And Minimum Detectable Change For Common Clinical Physical Function Tests In Sarcopenic Men And Women, Nathaniel D.M. Jenkins, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

Objectives: To determine the test–retest reliability and minimum detectable change scores for seven common clinical measurements of muscle strength and physical function in a multiethnic sample of sarcopenic, malnourished men and women.

Design: Each participant visited the laboratory seven times over 25 to 26 weeks. Reliability was assessed for each measurement from Familiarization 1 to Familiarization 2 (R1), Familiarization 2 to baseline testing (R2), Familiarization 3 to 12-week testing (R3), and Familiarization 4 to 24-week testing (R4).

Setting: Data were collected during a clinical trial at 23 sites in the United States, Belgium, Italy, Mexico, Poland, Spain, Switzerland, and the …

Using Pentosidine And Hydroxyproline To Predict Age And Sex In An Avian Species, Brian S. Dorr, Randal S. Stahl, Katie C. Hanson-Dorr, Carol A. Furcolow

USDA Wildlife Services: Staff Publications

All living organisms are subject to senescence accompanied by progressive and irreversible physiological changes. The error damage and cross-linking theories suggest that cells and tissues are damaged by an accumulation of cross-linked proteins, slowing down bodily processes and resulting in aging. A major category of these cross-linked proteins are compounds called advanced glycation end products (AGEs). We investigated the relationship between accumulation of the AGE, pentosidine (Ps), and hydroxyproline (HYP) a post-translationally modified amino acid, with age, sex, and breeding status (breeder/ nonbreeder) from skin samples of known age (i.e., banded as fledglings), free-ranging Double-crested Cormorants (Phalacrocorax auritus, …

A Dataset For Assessing Temporal Changes In Gene Expression During The Aging Process Of Adult Drosophila Melanogaster, Kimberly A. Carlson, Chi Zhang, Lawrence G. Harshman

School of Biological Sciences: Faculty Publications

A Drosophila melanogaster genome-wide transcriptome dataset is

available for studies on temporal patterns of gene expression. Gene

expression was measured using two-dye color oligonucleotide arrays

derived from Version 2 of the Drosophila Genomics Resource Center.

A total of 15,158 oligonucleotide probes corresponded to a high

proportion of the coding genes in the genome. The source of the flies

was a highly genetically heterogeneous population maintained in an

overlapping generation population regime. This regime was

designed to maintain life history traits so that they were similar to

those found in natural populations. Flies collected for the cohorts

were obtained in a …

Sestrin2, A Regulator Of Thermogenesis And Mitohormesis In Brown Adipose Tissue, Seung-Hyun Ro, Ian Semple, Allison Ho, Hwan-Woo Park, Jun Hee Lee

Department of Biochemistry: Faculty Publications

Sestrin2 is a stress-inducible protein that functions as an antioxidant and inhibitor of mTOR complex 1. In a recent study, we found that Sestrin2 overexpression in brown adipocytes interfered with normal metabolism by reducing mitochondrial respiration through the suppression of uncoupling protein 1 (UCP1) expression. The metabolic effects of Sestrin2 in brown adipocytes were dependent on its antioxidant activity, and chemical antioxidants produced similar effects in inhibiting UCP1-dependent thermogenesis. These observations suggest that low levels of reactive oxygen species (ROS) in brown adipocytes can actually be beneficial and necessary for proper metabolic homeostasis. In addition, considering that Sestrins are ROS …

Production Management Factors Affecting Inherent Beef Flavor: The Role Of Post-Weaning Forage, Energy Supplementation, Finishing Diets, And Aging Periods, Kimberly A. Varnold

Department of Animal Science: Dissertations, Theses, and Student Research

Projects were conducted to determine effects of diet and aging periods on inherent beef flavor characteristics by relating biochemical constituents of meat, consumer acceptability, and lexicon flavor notes of two different muscles. Prediction equations were also created. Warm-season grasses caused increased concentrations of moisture, heme iron, and zinc in L. dorsi steaks. Aging 28 d instead of 7 d caused increased pH, carbohydrate, and heme and non-heme iron concentrations in B. femoris steaks. Warm-season grasses caused decreased concentrations in a majority of fatty acids, specifically when supplementation was not provided. Few differences were observed with cool-season grasses. Provision of wet …

Nf05-636 Depression, Myrna Dubois

University of Nebraska-Lincoln Extension: Historical Materials

Feeling a little down? Discouraged? Those feelings are normal when life's challenges confront us from time to time. The feeling of discouragement usually goes away with a reasonable length of time. Depression, however, can hang around for weeks, months, even years.

This NebFacts discusses the two types of depression, their effects, resolution and treatment.

Nf04-622 Senior Gambling In The United States, Debra E. Schroeder, Mary Ann Holland

University of Nebraska-Lincoln Extension: Historical Materials

For an increasing number of older citizens, retirees ages 65 and up, casino gambling has become a new form of recreation and entertainment. Older adults now form the largest age group of annual visitors to Las Vegas and have become a significant segment of the population who frequent riverboat, Indian reservation, and the commercial gambling casino industry.

This NebFact discusses the prevalence, gambling opportunities, consequences, and common signs of senior gambling. It also discusses where to go for help for these senior gamblers.

Mental Health And Aging, Kathy Bosch

University of Nebraska-Lincoln Extension: Historical Materials

Mentally healthy people have the ability to respond to others, to love and be loved, and to cope with others in give-and-take relationships.

Nf579 Aging Sexuality, Kathy Bosch

University of Nebraska-Lincoln Extension: Historical Materials

Contrary to popular belief, the elderly are sexual beings. Each person is created to be a sexual being with normal desires of wanting to be loved and touched. Our culture tends to believe that love and sex belong only to the younger generations but many older adults enjoy being loved, touched and having sexual relations.

Grief — A Human Experience, Kathy Bosch

University of Nebraska-Lincoln Extension: Historical Materials

Like stress, grief is a part of everyone’s life, but it seems to happen more often when a person gets older. Grief can be caused by any loss.

Common Stressors For Aging Adults, Kathy Bosch

University of Nebraska-Lincoln Extension: Historical Materials

Mental health is not easy to define, but aging successfully should mean a person has good mental health. This does not mean older adults will never experience any problems or diseases, but that symptoms will be treated and controlled. Mental health problems should not interfere with leading a rewarding life.

Depression In Later Life, Kathy Bosch

University of Nebraska-Lincoln Extension: Historical Materials

We all understand feeling sad or "blue" from time to time. Personal losses or crises can leave us with low energy and a sense of unhappiness. These reactions are a normal part of living. But depression and depressive symptoms in the older individual present unique challenges.

How Can I Help An Older Person Who May Have A Mental Illness?, Kathy Bosch

University of Nebraska-Lincoln Extension: Historical Materials

Even though many persons suffer with a mental illness or disease at some point in their lives, these problems are treatable.

G92-1117 The Sandwich Generation: A Cluttered Nest, Herbert G. Lingren, Jayne Decker

University of Nebraska-Lincoln Extension: Historical Materials

The needs of three generations and solutions to resolve their stresses are covered here.

Lisa and Bruce both have careers. They have a teen-age son, a college student daughter, a recently divorced daughter with a one-year-old child, and an elderly mother who needs an increasing amount of caregiving, all living in the same household. They are classic members of the sandwich generation.

In the 1990s, people live longer, they postpone marriage, more children are living at home to go to college, and an increasing number of adult children are returning home after a divorce or loss of job. Consequently, larger …

Heg87-223 Understanding Grief And Loss, Herbert G. Lingren

University of Nebraska-Lincoln Extension: Historical Materials

This guide defines loss, offers guidelines for dealing with grief and loss, presents psychological and emotional responses to loss, and describes ways to help people deal with bereavement.

Loss is defined as a "separation from, a detachment from something or someone of value." The magnitude of the loss and its meaning and value to the individual affects the intensity of a person's response. Therefore, it is virtually impossible to predict how any one person will respond to a particular loss. But it always causes some change in perception of one's self or lifestyle and some type of adaptation or adjustment …

Heg86-210 Being A 'Grand' Parent, Herbert G. Lingren

University of Nebraska-Lincoln Extension: Historical Materials

This guide explores grandparenting, including the benefits derived from being a grandparent, suggestions on how to be a good grandparent, precautions to take when grandchildren come for a visit, and ways to have fun with grandchildren.

Grandparents Today

Approximately 75 percent of Americans over 65 have living grandchildren, according to a 1975 Harris poll. Most grandparents begin their role during middle age. The average age for becoming a grandmother is 46 and may be as early as 32. This means we need to set aside many outdated ideas about grandparent. They are active people. They do not necessarily get around …

Heg85-204 'Til Death Do Us Part...From The Minute After, Kathleen Prochaska-Cue

University of Nebraska-Lincoln Extension: Historical Materials

This NebGuide tells what to do after the death of a loved one, and how to plan to make your death easier for your survivors.

Death is a subject most people are uncomfortable discussing. But discussion and planning in advance of the death of someone close to you can save anguish -- and dollars.

This publication provides a checklist of what needs to be done immediately after a death, including a list of who needs to be notified, guidelines for decision-making immediately and sometime after death, sources of help for the survivors and suggestions on how to make your death …

G76-279 Processing Deer, Glenn W. Froning, P. S. Gipson

University of Nebraska-Lincoln Extension: Historical Materials

It is important to process game properly to obtain maximum flavor and storage stability.

It is a pleasure to hunt game, but perhaps an even greater satisfaction comes from eating the meat. In order to have a flavorful experience, the game animal must be handled, processed and prepared properly. If the game is improperly processed or handled, one may lose much of the desirable flavor and storage stability.