Life Sciences Commons^™

Filarial Genomics, Steven A. Williams

Biological Sciences: Faculty Publications

No abstract provided.

The Great Escape: Phosphorylation Of Ena/Vasp By Pka Promotes Filopodial Formation, Timothy M. Gomez, Estuardo Robles

Neuroscience: Faculty Publications

The Ena/VASP family of proteins consists of adaptor molecules that localize to subcellular sites of actin polymerization. The role of Ena/VASP proteins in the regulation of cell motility and axon outgrowth has been controversial. Recently, these proteins have been proposed to function as "anticapping" factors, which may have differential effects on filopodial versus lammelipodial actin-based protrusions. A study by Lebrand et al. in this issue of Neuron supports this model and identifies PKA as a key regulator of Ena/VASP function downstream of the chemoattractant Netrin.

Inhibition Of Nitric Oxide Inhibition Of Nitric Oxide Synthase Does Not Alter Dynamic Cerebral Autoregulation In Humans, Rong Zhang, Thad E. Wilson, Sarah Witkowski, Jian Cui, Craig G. Crandall, Benjamin D. Levine

Exercise and Sport Studies: Faculty Publications

The aim of this study was to determine whether inhibition of nitric oxide synthase (NOS) alters dynamic cerebral autoregulation in humans. Beat-to-beat blood pressure (BP) and cerebral blood flow (CBF) velocity (transcranial Doppler) were measured in eight healthy subjects in the supine position and during 60° head-up tilt (HUT). NOS was inhibited by intravenous N G-monomethyl-L-arginine (L-NMMA) infusion. Dynamic cerebral autoregulation was quantified by transfer function analysis of beat-to-beat changes in BP and CBF velocity. Pressor effects of L-NMMA on cerebral hemodynamics were compared with those of phenylephrine infusion. In the supine position, L-NMMA increased mean BP from 83 ± …

Vasoconstrictor Reserve And Sympathetic Neural Control Of Orthostasis, Qi Fu, Sarah Witkowski, Benjamin D. Levine

Exercise and Sport Studies: Faculty Publications

Background—We tested the hypothesis that individual variability in orthostatic tolerance is dependent on the degree of neural and vasomotor reserve available for vasoconstriction.

Methods and Results—Muscle sympathetic nerve activity (MSNA) and hemodynamics were measured in 12 healthy young volunteers during 60° head-up tilt (HUT), followed by a cold pressor test (CPT) in HUT. Orthostatic tolerance was determined by progressive lower-body negative pressure (LBNP) to presyncope. The same protocols were performed randomly in normovolemic and hypovolemic conditions. We found that mean arterial pressure increased and stroke volume decreased, whereas heart rate (HR), MSNA, and total peripheral resistance (TPR) increased during HUT …

Effect Of Zooid Spacing On Bryozoan Feeding Success: Is Competition Or Facilitation More Important?, Marney C. Pratt

Biological Sciences: Faculty Publications

Most Recent bryozoan species are encrusting sheets, and many of these colonies have densely packed feeding zooids. In this study, I tested whether tight packing of feeding zooids affects food capture. Colonies of a bryozoan with an encrusting sheet form (Membranipora membranacea) were dissected to produce individuals whose feeding zooids were (1) closely packed, (2) more widely spaced, or (3) isolated. For each type, rates of particle ingestion were measured in still water and in a freestream velocity of 2.7 cm s-1. Ingestion rate increased when zooids were closest together, probably because of reduced refiltration and increased feeding current strength …

Shallow-Water Coral Reefs In Transition: Examples From Belize And The Bahamas, H. Allen Curran, Paulette M. Peckol, Benjamin J. Greenstein, Shannon Ristau, Susan Deyoung

Geosciences: Faculty Publications

Reprinted from: Ronald D. Lewis and Bruce C. Panuska (eds.) Proceedings of the 11th Symposium on the Geology of the Bahamas and Other Carbonate Regions: San Salvador, Gerace Research Center