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Imperatorin A Furocoumarin Inhibits Periplasmic Cu-Zn Sod Of Shigella Dysenteriae Their By Modulates Its Resistance Towards Phagocytosis During Host Pathogen Interaction, Raja Sb, Murali Mr, Roopa K, Devaraj Sn
Imperatorin A Furocoumarin Inhibits Periplasmic Cu-Zn Sod Of Shigella Dysenteriae Their By Modulates Its Resistance Towards Phagocytosis During Host Pathogen Interaction, Raja Sb, Murali Mr, Roopa K, Devaraj Sn
Murali Malliga Raman
Shigella dysenteriae continues to be a major health problem, which leads to death, due to diarrhoea and dysentery, predominantly in children below the age of 5. Bacterial invasion of the colonic epithelium leads to severe inflammation together with bacterial dissemination generates abscesses and ulcerations. Periplasmic copper, zinc super oxide dismutase of Shigella protects it from exogenous superoxide produced by host, during its invasion. Hence, in present study an attempt was made to study the effect of aqueous extract of Aegle marmelos on host and pathogen defence. Histology analysis of rat ileal loop showed the loss of virulence in aqueous extract …