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Full-Text Articles in Life Sciences
The Effects Of Propofol, Sodium Pentobarbital, And Ketamine Hydrochloride On In Vitro Mouse Embryonic Development, Tyler C. Balak
The Effects Of Propofol, Sodium Pentobarbital, And Ketamine Hydrochloride On In Vitro Mouse Embryonic Development, Tyler C. Balak
Theses and Dissertations in Biomedical Sciences
Every year more than 75,000 pregnant women are exposed to teratogenic medications or general anesthesia during non-obstetric surgery in the US,1-4 and embryonic effects of general anesthesia are of particular interest in laboratory research and veterinary medicine. The mouse system is used to screen potential toxic effects of anesthetics used in egg retrieval for in vitro fertilization (IVF), or those of pharmacologic agents which may come in contact with the egg or early embryo. Mouse preimplantation 2-cell embryos were exposed in vitro to incremental concentrations of common general anesthetics within and exceeding the normal clinical dosage range for mice (propofol …
Exploring The Neuropeptides, Neuropeptide Receptors And Neurotransmitter Receptors In The Synganglia Of Part-Fed Females Of Ornithodoros Turicata (Argasidae) And Ixodes Scapularis (Ixodidae) With Insights Into Their Roles In Contrasting Biology, Noble I. Egekwu
Theses and Dissertations in Biomedical Sciences
The neurobiology of the synganglion (central nervous system) of the Lyme disease tick, Ixodes scapularis and the soft tick Ornithodoros turicata was evaluated using Illumina GAII high throughput sequencing which generated high coverage cDNA libraries (transcriptomes). These ticks exhibit different biological patterns of feeding, blood meal water, and salt elimination, cuticle plasticity versus cuticle synthesis, development and reproduction. RNA sequencing of I. scapularis, and Ornithodoros turicata yielded a total of 117,900,476 raw reads which were assembled to 30,838 contigs and a total of 63,528,102 also assembled to 132,258 contigs, respectively. Comparison of Gene Ontology (GO) mapping success for genes …