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Full-Text Articles in Life Sciences

Doxycycline Resistance In Plasmodium Falciparum Linked To Single Nucleotide Polymorphisms In The Plasmodium Falciparum Apicoplast Small Subunit Ribosomal Rna (Pfssrrna) Gene, Amanda Wasko Apr 2016

Doxycycline Resistance In Plasmodium Falciparum Linked To Single Nucleotide Polymorphisms In The Plasmodium Falciparum Apicoplast Small Subunit Ribosomal Rna (Pfssrrna) Gene, Amanda Wasko

Scholarly and Creative Works Conference (2015 - 2021)

Plasmodium falciparum, a protozoan parasite known as malaria, widely impacts human health; thus antimalarial drug investigations are critical. Doxycycline is a commonly used antimalarial prophylactic, but its mechanism of action is unclear. In prokaryotes, doxycycline works as an antibacterial by disrupting protein translation via the small subunit ribosome. Interestingly, P. falciparum has a small subunit ribosome of prokaryotic origins in the apicoplast, a plastid-like organelle. Therefore, we hypothesized that doxycycline works in P. falciparum by inhibiting protein synthesis via the small subunit ribosomal RNA and that mutations in the gene encoding the P. falciparum apicoplast small subunit ribosomal RNA …


Movies With Meaning: Crossing Disciplines In Cinema, Ashley Cotter Apr 2016

Movies With Meaning: Crossing Disciplines In Cinema, Ashley Cotter

Scholarly and Creative Works Conference (2015 - 2021)

One might not realize that blockbuster movies can be used as an educational tool in the classroom setting to enhance the learning process. While these types of movies are not crafted as pedagogical tools, like animated, demonstrative video clips, there is educational value to be found in them. In more recent years, this is a practice that has been used in many classrooms. However, it is within the social sciences primarily that these blockbuster films are used to augment the understanding of concepts. Big films are rarely, if ever, used in the hard sciences to provide examples of concepts. How …