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Life Sciences Commons

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Colby College

Biology

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2014

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Analysis Of Current Clinical Antiviral Treatment Approaches And Medications And Related Suggestions For Future Research, Daniel Sunderland May 2014

Analysis Of Current Clinical Antiviral Treatment Approaches And Medications And Related Suggestions For Future Research, Daniel Sunderland

CLAS: Colby Liberal Arts Symposium

Viral pathogens present researchers, physicians, and public health workers with the challenges of developing new treatments in an every-changing landscape of antiviral drug resistance. This paper outlines the basis of current knowledge in virology, how that knowledge is applied when developing treatments such as integrase and protease inhibitors, neuraminidase inhibitors, nucleotide analogs, and others, and considers the rates of resistance of the target viruses to those treatments. There is also some consideration of immunomodulatory treatments and the potential of viral vectors as a means of understanding different immune responses to viruses and the direct effects that viruses can have on …