Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Pharmacology, Toxicology and Environmental Health (3)
- Social and Behavioral Sciences (3)
- Toxicology (3)
- Biology (2)
- Forensic Science and Technology (2)
-
- Legal Studies (2)
- Neuroscience and Neurobiology (2)
- Animal Sciences (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Cell Biology (1)
- Cell and Developmental Biology (1)
- Computational Neuroscience (1)
- Computer Sciences (1)
- Entomology (1)
- Epidemiology (1)
- Genetics (1)
- Genetics and Genomics (1)
- Medicine and Health Sciences (1)
- Molecular Biology (1)
- Molecular Genetics (1)
- Numerical Analysis and Scientific Computing (1)
- Other Animal Sciences (1)
- Other Life Sciences (1)
- Other Neuroscience and Neurobiology (1)
- Other Psychology (1)
- Other Public Health (1)
- Personality and Social Contexts (1)
- Physical Sciences and Mathematics (1)
- Psychology (1)
- Keyword
-
- Trypsin (2)
- Barbiturates (1)
- Biological evidence (1)
- Brain data (1)
- Cartridge casings (1)
-
- Co-extraction (1)
- DNA typing (1)
- Direct PCR (1)
- ELISA (1)
- ERP (1)
- Eeg (1)
- Emotional processing (1)
- Empathic concern (1)
- Empathy (1)
- Extraction (1)
- Fingerprints (1)
- Forensic (1)
- Hair (1)
- Hurst parameter (1)
- Liquid chromatography; mass spectrometry; solid phase extraction; wastewater; opioid; cannabis (1)
- N400 (1)
- Protein (1)
- Protein polymorphisms (1)
- Psychopathy (1)
- STR multiplex (1)
- Screening (1)
- Self-similarity (1)
- Touch DNA (1)
- Urine; lemur; gas chromatography-mass spectrometry; cyanide; thiocyanate; 2-aminothiazioline-4-carboxyclic acid. (1)
Articles 1 - 9 of 9
Full-Text Articles in Life Sciences
Identification And Quantification Of Cyanide And Its Metabolites In Lemur Urine, Jeremy Peralta
Identification And Quantification Of Cyanide And Its Metabolites In Lemur Urine, Jeremy Peralta
Student Theses
Cyanide is a chemical compound that contains the monovalent groups of carbon and nitrogen. This substance is considered a rapidly acting deadly chemical. However, some animals such as lemurs consume food products that are known to contain elevated levels of cyanide without major consequences. The mechanism by which the lemur can handle this high exposure to cyanide is unknown. In this study, we developed and validated two analytical methods for the determination of cyanide and two metabolites, thiocyanate and 2-aminothiazoline-4-carboxylic acid (ATCA) in lemur urine. The method was applied to 47 authentic lemur urine samples collected from 4 different species …
Evaluation Of A Direct Pcr Method And The Qiagen Investigator 24plex Go! Kit For Typing Blood, Saliva And Touch Dna On Multiple Substrates, Angelita Pierre-Noel
Evaluation Of A Direct Pcr Method And The Qiagen Investigator 24plex Go! Kit For Typing Blood, Saliva And Touch Dna On Multiple Substrates, Angelita Pierre-Noel
Student Theses
In forensic DNA typing, omitting the DNA extraction procedure and adding the sample directly to the polymerase chain reaction (direct PCR) mixture has several advantages. Without extraction and purification, there is less of a risk of sample loss, sample mix up, or contamination. This study tested the feasibility of direct PCR using the Qiagen® Investigator® 24plex GO! Kit, a megaplex kit that amplifies 22 polymorphic STR markers and the Amelogenin sex determination alleles. Test samples included blood, saliva and skin cells on porous substrates, specifically denim, white cotton, polyester fabric, and paper tissue. Glass slides were used to represent non-porous …
Study Of Self-Similarity In Brain Data, Jennifer Holst
Study Of Self-Similarity In Brain Data, Jennifer Holst
Student Theses
In the area of computer science, past research has found that the concept of self-similarity is present in local and Internet-based network traffic. This study considers the possibility that data traveling through the neuronal network in the human brain is also self-similar. By analyzing publicly available raw EEG data and estimating its Hurst parameter, we find indications that brain data traffic may in fact be self-similar.
Optimizing A Method For Simultaneous Recovery Of Proteins And Dna From Fingerprints, Steven Kranes
Optimizing A Method For Simultaneous Recovery Of Proteins And Dna From Fingerprints, Steven Kranes
Student Theses
DNA testing on touched objects is a valuable tool in forensic investigations, but DNA is usually present in low amounts, causing poor STR typing results. For touch DNA evidence, there is a clear need for additional individualization, especially for highly probative samples. This could be achieved by testing genetically variable proteins. The goal of this project was to develop a DNA/protein co-extraction method to facilitate DNA and protein testing on the same evidence item. Existing DNA extraction methods were carefully adjusted to allow for downstream mass spectrometry analysis. Initial experiments on saliva and fingerprints placed on glass suggested that trypsin …
Range Of Detection For Proteins And Dna From Fingerprints On Fired And Unfired Cartridge Casings, Stacey-Ann R. Sterling
Range Of Detection For Proteins And Dna From Fingerprints On Fired And Unfired Cartridge Casings, Stacey-Ann R. Sterling
Student Theses
Cartridges and spent cartridge casings can be probative pieces of evidence. Unfortunately due to a combination of factors such as exposure to high temperatures and initially low amounts of biological material on the surface, DNA testing so far has been mostly unsuccessful for these items. Typing other marker systems, such as protein polymorphisms, on the same biological evidence would add power of discrimination. To explore this option we developed a DNA-protein trypsin-based co-extraction method that was optimized for unfired and fired cartridges. Various sample wet and dry collection methods and multiple metal casings, such as aluminum, nickel, steel, and brass …
A Validation Of The Detection Of Barbiturates In Hair By Elisa, Alisa M. Valentino
A Validation Of The Detection Of Barbiturates In Hair By Elisa, Alisa M. Valentino
Student Theses
An original method to extract and detect barbiturates, specifically secobarbital, in hair by enzyme-linked immunosorbent assay (ELISA), has been developed. Drug-free hair specimens were fortified with an exaggerated amount of secobarbital to produce a homogeneous, true positive sample to be utilized to test the drug extraction efficiency from hair. Drug extraction using hair extraction buffer (HEB) from Immunalysis was compared to a base digestion using 1M NaOH. After LCMS/MS analysis, HEB extraction was deemed a successful method for extracting barbiturates from hair. Using this method, the Barbiturates Direct ELISA Kit from Immunalysis was evaluated for its potential use in the …
Psychopathy, Empathic Concern, And Emotional-Sentence Processing: An N400 Erp Study, Farren Larson
Psychopathy, Empathic Concern, And Emotional-Sentence Processing: An N400 Erp Study, Farren Larson
Student Theses
Using an undergraduate sample, the present study examined how psychopathic traits (assessed by the Psychopathic Personality Inventory-Revised) and empathic concern (assessed by the Interpersonal Reactivity Index) affect emotional-information processing using event-related potentials (ERPs) and a sentential priming paradigm. Participants had their electroencephalogram (EEG) recorded while they silently read sentences with three types of endings: congruent, incongruent, and emotionally negative. We hypothesized that participants with high levels of psychopathic traits and participants with low levels of empathic concern would find the emotionally negative sentence endings less unexpected and disturbing (yielding a smaller N400), compared to participants with low levels of psychopathic …
Quantitative Analysis Of Opioids And Cannabinoids In Wastewater Samples, Alethea Jacox
Quantitative Analysis Of Opioids And Cannabinoids In Wastewater Samples, Alethea Jacox
Student Theses
Wastewater-based epidemiology is an innovative approach that uses the analysis of human excretion products in wastewater to obtain information about exposure to drugs in defined population groups. We developed and validated an analytical method for the detection and quantification of opioids (morphine, oxycodone, hydrocodone, oxymorphone and hydromorphone), and cannabinoids (9-tetrahydrocannabinol, 11-nor 9-carboxy- tetrahydrocannabinol (THCCOOH) and THCCOOH-glucuronide) in raw influent wastewater samples by ultra-high performance liquid chromatography-tandem mass spectrometry. Method validation included linearity (5–1 000 ng/L for opioids, 10–1 000 ng/L for cannabinoids), imprecision (<21.2%), accuracy (83%–131%), matrix effect (from –35.1% to –14.7%) and extraction efficiency (25%–84%), limit of detection (1–5 ng/L) and quantification (5–10 ng/L) and auto-sampler stability (no loss detected). River, sewage overflow and wastewater samples were collected in triplicate from different locations in New York City and stored at -20 C until analysis. River water samples were negative for all the compounds. Water from sewage overflow location tested positive for morphine (10.7 ng/L), oxycodone (4.2–23.5 ng/L), oxymorphone (4.8 ng/L) and hydromorphone (4.2 ng/L). Wastewater samples tested positive for morphine (133.0– 258.3 ng/L), oxycodone (31.1– 63.6 ng/L), oxymorphone (16.0–56.8 ng/L), hydromorphone (6.8–18.0 ng/L), hydrocodone (4.0– 12.8 ng/L) and THCCOOH (168.2– 772.0 ng/L). This method is sensitive and specific for opioids and marijuana determination in wastewater samples.
The Effect Of Resource Quality And Species Interactions On The Colonization Behavior Of The Black Blow Fly, Phormia Regina (Meigen), Melissa N. Branker
The Effect Of Resource Quality And Species Interactions On The Colonization Behavior Of The Black Blow Fly, Phormia Regina (Meigen), Melissa N. Branker
Student Theses
During decomposition, there are many different insects groups that utilize carrion as a resource. In particular, blow flies (Order: Diptera; Family: Calliphoridae) are considered to be a forensically important family due to their ability to rapidly locate and colonize a carrion resource. As a result, blow flies are commonly used as indicator species in PMI estimations. However, recent research indicates that the colonization behavior of these species can be influenced by a variety of abiotic and biotic factors. In this study, the effects of arrival order, resource quality and bacterial or species cues on the oviposition behavior of Phormia regina …