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Western Kentucky University

International Journal of Exercise Science

2017

Gene expression

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Irisin And Fibronectin Type Iii Domain-Containing 5 Responses To Exercise In Different Environmental Conditions, Matthew Bubak, Matthew W.S. Heesch, Robert J. Shute, Nicholas E. Dinan, Terence L. Laursen, D. Taylor La Salle, Dustin R. Slivka Aug 2017

Irisin And Fibronectin Type Iii Domain-Containing 5 Responses To Exercise In Different Environmental Conditions, Matthew Bubak, Matthew W.S. Heesch, Robert J. Shute, Nicholas E. Dinan, Terence L. Laursen, D. Taylor La Salle, Dustin R. Slivka

International Journal of Exercise Science

International Journal of Exercise Science 10(5): 666-680, 2017. Fibronectin type III domain-containing 5 (FNDC5) is a skeletal muscle membrane-bound precursor to the myokine irisin. Irisin is involved in stimulating adipose tissue to become more metabolically active in order to produce heat. The purpose of this study was to determine the effects of exercise in a hot (33 °C), cold (7 °C), and room temperature (RT, 20 °C) environment on the skeletal muscle gene expression of FNDC5 and the plasma concentrations of irisin. Twelve recreationally trained males completed three separate, 1 h cycling bouts at 60% of Wmax in a …