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- Acute toxicity (2)
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Articles 1 - 7 of 7
Full-Text Articles in Life Sciences
Physico Chemical, Azhagu Raj Ramakrishnan
Physico Chemical, Azhagu Raj Ramakrishnan
Azhaguraj Ramakrishnan
No abstract provided.
Acute Toxicity Of Mercury And Chromium To Clarias Batrachus (Linn), Azhaguraj Ramakrishnan
Acute Toxicity Of Mercury And Chromium To Clarias Batrachus (Linn), Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
Pollution of the aquatic ecosystems by heavy metals is a worldwide problem. In the present study, Clarias batrachus was exposed to Mercury and Chromium for 24, 48, 72 and 96 hrs. The median lethal concentration (LC50) of mercury to C. batrachus for 24, 48, 72 and 96 h of exposure were 1.4 ppm, 1.2 ppm, 1.0 ppm and 0.8 ppm respectively. The median lethal concentration (LC50) of chromium to C. batrachus for 24, 48, 72 and 96 h of exposure were 120 ppm, 115 ppm, 110 ppm and 102 ppm respectively. The acute toxicity levels were derived from LC50 concentrations …
Quantitative Variation Of Protein In The Tissues Of A Fresh Water Fish Clarias Batrachus Exposed To Mercury And Chromium, Azhaguraj Ramakrishnan
Quantitative Variation Of Protein In The Tissues Of A Fresh Water Fish Clarias Batrachus Exposed To Mercury And Chromium, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
The present study was carried out to determine the effects of sub-lethal concentration (96 h-LC50) of mercury .026ppm, 0.040ppm and 0.080ppm) and chromium (3.4ppm, 5.1ppm and 10.2ppm) for 28 days in Clarias batrachus and the protein content in the brain, gills, liver, kidney and muscle were quantified Bradford method. The levels of protein content in the liver, kidney, brain, muscle and gill showed fluctuations of decreasing and increasing trend in fishes exposed to different concentrations of mercury and chromium in a time–dosedependent manner.The protein variation in the tissues of C.batrachus were significant when exposed in mercury and chromium. The variations …
Toxic Effects And Bioaccumulation Of Cadmium, Copper, Lead And Zinc In Post Larval Stages Of Penaeus Monodon, Azhaguraj Ramakrishnan
Toxic Effects And Bioaccumulation Of Cadmium, Copper, Lead And Zinc In Post Larval Stages Of Penaeus Monodon, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
The acute toxicity and bioaccumulation of cadmium, copper, lead and zinc to Penaeus monodon (Tiger prawn) was evaluated in static tests. Each test lasted up to 4 d and LC50 values were also calculated. The toxicity of each metal increased with exposure time for cadmium, copper, lead and zinc. The 96 hours LC50 values for cadmium, copper, lead and zinc were 1.72, 0.66, 0.41, 2.36 mg/l. Lead was toxic metal to P.monodon than zinc followed by cadmium and copper tested. The order of toxicity was Pb>Cu>Cd>Zn. The bioaccumulation study showed that the zinc was accumulated in a …
Homology Modeling And In Silico Analysis Of Cox From Channa Punctata, Azhaguraj Ramakrishnan
Homology Modeling And In Silico Analysis Of Cox From Channa Punctata, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
The Cytochrome c oxidase (COX) region of mitochondrial DNA is the most studied region of the fish mitochondrial genome. COX is one of the largest protein coding genes of metazoan mitochondrial genome.COX (E.C.1.9.3.1) is the terminal member of the respiratory chain catalyzing the reduction of dioxygen to water by ferrocytochrome C. A 19.927 kDa COX has been characterized in Channa punc-tata where COX III dimensional structure was generated using Deep View/ Swiss Pdp Viewer 3.7(Sps) by homol-ogy modeling, predicted model was validated in RAM-PAGE Server and COX secondary structure is predicted by PSIPRED, PHYRE and TNHMM Server. Protein statics was …
Abd: Advanced Biotechnological Directory For Protein Sequence And Structure Analysis, Azhaguraj Ramakrishnan
Abd: Advanced Biotechnological Directory For Protein Sequence And Structure Analysis, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
Over the past decades, a number of computational tools for structure prediction have been developed. It is critical that the biological community is aware of such tools and is able to interpret their results in an informed way. Rapid increase in protein sequence information from genome sequencing projects demand the intervention of bioinformatics tools to recognize interesting gene products and associated function often multiple algorithms need to be employed to improve accuracy in prediction and several structure prediction. Here we report the availability of an ABD as a bioinformatics online package dedicated for Insilco analysis of protein sequence and structure …
Predication Of Biological Activity Of Algal Antitumor Drugs Using Pass, Azhaguraj Ramakrishnan
Predication Of Biological Activity Of Algal Antitumor Drugs Using Pass, Azhaguraj Ramakrishnan
Azhaguraj Ramakrishnan
The computer system PASS provides simultaneous predication of several hundreds of biological activity types of any drug like compounds. Over the past decade seaweeds have become an interesting source of new classes of pharmacologically active natural products. The majority of biologically active compounds have both pharmacotherapeutic and side/toxic actions. To estimate general efficacy and safety of the molecules under study, their biological potential should be thoroughly evaluated. In this study the PASS (Predication of activity spectra for substances)computer program, which is able to simultaneously predict more than one thousand biological and toxicological activities from only the structural formulas of the …