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Full-Text Articles in Life Sciences

Synthesis Of Novel Sugar Diamino Acids, M Thillakan, A Katsifis, D Skropeta Nov 2013

Synthesis Of Novel Sugar Diamino Acids, M Thillakan, A Katsifis, D Skropeta

Danielle Skropeta

Sugar amino acids (SAAs) are found in nature as good construction elements for the preparation of peptide mimetics and oiigosaccharides in drug design and development. The synthesis of SAAs is readily accomplished in few steps and more than 40 SAAs have been synthesised to date.2 Sugar amino acids with an additional amino group, the sugar diamino acid (SDAs) would represent a useful expansion to the library of SAAs available because one of the amino group and carboxylic acid is available for peptide coupling and the another amino/azide group allow to do further derivatisation via peptide or click chemistry such as …


Exploring Marine Resources For New Pharmaceutical Applications, Danielle Skropeta Nov 2013

Exploring Marine Resources For New Pharmaceutical Applications, Danielle Skropeta

Danielle Skropeta

No abstract provided.


Valuing Water: Variability And The Lake Eyre Basin, Central Australia, Leah Gibbs Sep 2013

Valuing Water: Variability And The Lake Eyre Basin, Central Australia, Leah Gibbs

Leah Maree Gibbs

'Environmental values' form an increasingly important component of natural resource management, but use of the term 'value' is dominated by a narrow and limiting utility-based definition. In this paper I consider theories of value and practices of valuing water in the arid and semi-arid Lake Eyre Basin, central Australia. While value is the subject of diverse meanings - both within a range of academic disciplines and as understood by people in specific places - methods of valuing water in natural resource management are limited by reductionism, anthropocentrism and cultural specificity. This conceptualisation of value does not adequately capture what people …


Parcel Subdivision Automation For Agent-Based Land Use Modelling, Rohan Wickramasuriya, Laurie Chisholm, Marji Puotinen, Nicholas Gill, Peter Klepeis Sep 2013

Parcel Subdivision Automation For Agent-Based Land Use Modelling, Rohan Wickramasuriya, Laurie Chisholm, Marji Puotinen, Nicholas Gill, Peter Klepeis

Rohan Wickramasuriya, Ph.D.

To a significant extent rural Australia is transforming into multifunctional landscapes. Amenity migration (i.e. movement of people from metropolitan to rural settings) is a major driving force of this transition in many areas. However, the effects of amenity migration on the receiving landscapes are not yet fully understood. Agent-based land use modelling helps unravel the complex spatio-temporal relationships that affect landscape response to change from amenity migration. A land subdivision module is essential for a complete agent-based land use model developed for these landscapes because the land sold to in-migrants are lots that are subdivided from much larger tracts. In …


Fibre: Male Participants Not Getting Enough, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Linda Tapsell, Marijka Batterham, Karen Charlton Aug 2013

Fibre: Male Participants Not Getting Enough, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Linda Tapsell, Marijka Batterham, Karen Charlton

Qingsheng Zhang

A regular intake of dietary fibre has been associated with a number of health benefits. Consuming a high fibre diet may significantly lower the risk of developing heart disease, stroke, hypertension, diabetes and obesity (Anderson et al, 2009). Foods high in fibre such as fruit, vegetables, legumes and wholegrains are regularly included in diets targeting weight loss as they are low in fat, sugar and salt and contain a number of vitamins and minerals. Participants in trials using healthy background diets may increase their fibre intake in addition to the study variables. The aim of this study was to report …


Start Date May Predict Attrition 6 Months Into A 12mth Dietary Intervention Weight Loss Trial, Jane O'Shea, Linda Tapsell, Marijka Batterham, Karen Charlton, Yasmine Probst, Rebecca Thorne, Qingsheng Zhang, Holley Jones Aug 2013

Start Date May Predict Attrition 6 Months Into A 12mth Dietary Intervention Weight Loss Trial, Jane O'Shea, Linda Tapsell, Marijka Batterham, Karen Charlton, Yasmine Probst, Rebecca Thorne, Qingsheng Zhang, Holley Jones

Qingsheng Zhang

Participant recruitment is a difficult and time consuming aspect of clinical trials, often resulting in delays and budget overruns. Having reached recruitment targets the next challenge is participant retention. Some weight-loss studies have attrition rates around 60% which may introduce bias in the results. It may be possible to reduce attrition rates if known predictors can be found but to date few studies produced consistent results. The aim of this exploratory study was to determine whether start date could be a predictor of attrition for participants involved in the SMART weight loss clinical trial (ACTRN12608000425392). Recruitment for the trial occurred …


Pork, Beef And Chicken Have Similar Effects On Acute Satiety And Hormonal Markers Of Appetite, Karen Charlton, Linda Tapsell, Marijka Batterham, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Eleanor Beck Aug 2013

Pork, Beef And Chicken Have Similar Effects On Acute Satiety And Hormonal Markers Of Appetite, Karen Charlton, Linda Tapsell, Marijka Batterham, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Eleanor Beck

Qingsheng Zhang

The effects of three different meat-containing breakfast meals (pork, beef or chicken) on acute satiety and appetite regulatory hormones were compared using a within-subjects study design. Thirty fasting non-smoking pre-menopausal women attended a research centre on three test days to consume, a meat-containing meal matched in energy (kJ) and protein content, palatability, and appearance. No difference was found between meat groups for either energy intake or macronutrient profile of food consume data subsequent ad libitum buffet lunch, or over the rest of the day. Visual Analogue Scale(VAS) ratings for hunger and satiety over an 180min period did not differ between …


Cholesterol-Lowering Effects Of B-Glucan Containing Breakfast Cereals And Snack Bars, Karen Charlton, Linda Tapsell, Marijka Batterham, Jane O'Shea, Rebecca Thorne, Qingsheng Zhang, Eleanor Beck Aug 2013

Cholesterol-Lowering Effects Of B-Glucan Containing Breakfast Cereals And Snack Bars, Karen Charlton, Linda Tapsell, Marijka Batterham, Jane O'Shea, Rebecca Thorne, Qingsheng Zhang, Eleanor Beck

Qingsheng Zhang

No abstract provided.


Intersectoral And Interagency Partnerships To Investigate Youth Help-Seeking And The Reponses Of At-Risk Young Men To Intervention Services, Coralie Wilson, Frank Deane, Joseph Ciarrochi Jul 2013

Intersectoral And Interagency Partnerships To Investigate Youth Help-Seeking And The Reponses Of At-Risk Young Men To Intervention Services, Coralie Wilson, Frank Deane, Joseph Ciarrochi

Coralie J Wilson

No abstract provided.


Engaging Young People In Mental Health Services: Overcoming Barriers To Appropriate Help-Seeking., Coralie Wilson, Frank Deane Jul 2013

Engaging Young People In Mental Health Services: Overcoming Barriers To Appropriate Help-Seeking., Coralie Wilson, Frank Deane

Coralie J Wilson

No abstract provided.


Doing Participatory Action Research And Doing A Phd: Words Of Encouragement For Prospective Students, Natascha Klocker Jul 2013

Doing Participatory Action Research And Doing A Phd: Words Of Encouragement For Prospective Students, Natascha Klocker

Natascha Klocker

No abstract provided.


Online Advertising: Examining The Content And Messages Within Websites Targeted At Children, Lisa Kervin, Sandra Jones, Jessica Mantei Jul 2013

Online Advertising: Examining The Content And Messages Within Websites Targeted At Children, Lisa Kervin, Sandra Jones, Jessica Mantei

Jessica Mantei

It is recognised that from a young age children spend considerable portions of their leisure time on the Internet. In Australia a number of child-targeted magazines have associated websites, which have high and ever-increasing readership. We do not yet know the impact of this medium upon children. Overt advertising is evident on webpages, but so too are hidden advertisements in the written text, images and games. This material usually does not comply with existing broadcasting codes of practice for mainstream advertising. This article examines the instances of overt and covert advertisements for food within three websites monitored over a 12-month …


Late Quaternary Aeolian And Fluvial Interactions On The Cooper Creek Fan And The Association Between Linear And Source-Bordering Dunes, Strzelecki Desert, Australia, Timothy Cohen, Gerald Nanson, Joshua Larsen, B. Jones, David Price, Maria Coleman, Tim Pietsch Jun 2013

Late Quaternary Aeolian And Fluvial Interactions On The Cooper Creek Fan And The Association Between Linear And Source-Bordering Dunes, Strzelecki Desert, Australia, Timothy Cohen, Gerald Nanson, Joshua Larsen, B. Jones, David Price, Maria Coleman, Tim Pietsch

B. G. Jones

The Innamincka Dome and associated low-gradient fan in the Strzelecki Desert is the product of Cenozoic crustal warping that has aided formation of an extensive array of palaeochannels, source-bordering transverse dunes and superimposed linear dunes. These dunes have impeded the course of Cooper Creek and provided a repository of evidence for Quaternary climate change as well as the interactive processes between transverse and linear dune formation. At Turra, Gidgealpa and sites nearby are extensive fluvial and aeolian sand bodies that date from marine isotope stages (MIS) 8-3 and the Last Glacial Maximum (LGM) and are now surrounded or buried by …


Healthy Eating And Physical Activity Challenges And Opportunities In After-School Programs: Providers’ Perspectives, Heather Thomas, L. Fellner, Patricia Tucker, Jennifer Irwin May 2013

Healthy Eating And Physical Activity Challenges And Opportunities In After-School Programs: Providers’ Perspectives, Heather Thomas, L. Fellner, Patricia Tucker, Jennifer Irwin

Trish Tucker

The purpose of this study was to understand after-school program providers’ perspectives of (a) current physical activity and nutrition curriculum, practices, and challenges, and (b) necessary modifications, program suggestions or resource needs to improve the healthy eating and active living practices within their after-school program for children aged 6 to 12 years. This qualitative study targeted a sample of nine after-school program providers in London, Ontario. Data was collected via in-depth interviews and a demographic survey between January and April 2009. Strategies to enhance data trustworthiness were incorporated throughout. After-school program providers identified insufficient healthy eating curriculum and requested interactive, …


Structural Characterization Of Clusterin-Chaperone Client Protein Complexes, Amy Wyatt, Justin Yerbury, Mark Wilson May 2013

Structural Characterization Of Clusterin-Chaperone Client Protein Complexes, Amy Wyatt, Justin Yerbury, Mark Wilson

Mark R Wilson

Clusterin (CLU) is a potent extracellular chaperone that inhibits protein aggregation and precipitation otherwise caused by physical or chemical stresses (e.g. heat, reduction). This action involves CLU forming soluble high molecular weight (HMW) complexes with the client protein. Other than their unquantified large size, the physical characteristics of these complexes were previously unknown. In this study, HMW CLU-citrate synthase (CS), HMW CLU-fibrinogen (FGN), and HMW CLU-glutathione S-transferase (GST) complexes were generated in vitro, and their structures studied using size exclusion chromatography (SEC), ELISA, SDS-PAGE, dynamic light scattering (DLS), bisANS fluorescence, and circular dichroism spectrophotometry (CD). Densitometry of …


Communication: New Insight Into The Barrier Governing Co2 Formation From Oh + Co, Christopher Johnson, Berwyck Poad, Ben Shen, Robert Continetti May 2013

Communication: New Insight Into The Barrier Governing Co2 Formation From Oh + Co, Christopher Johnson, Berwyck Poad, Ben Shen, Robert Continetti

Berwyck L. J. Poad

Despite its relative simplicity, the role of tunneling in the reaction OH + CO → H + CO(2) has eluded the quantitative predictive powers of theoretical reaction dynamics. In this study a one-dimensional effective barrier to the formation of H + CO(2) from the HOCO intermediate is directly extracted from dissociative photodetachment experiments on HOCO and DOCO. Comparison of this barrier to a computed minimum-energy barrier shows that tunneling deviates significantly from the calculated minimum-energy pathway, predicting product internal energy distributions that match those found in the experiment and tunneling lifetimes short enough to contribute significantly to the overall reaction. …


Dietary Methodology In Clinical Trials: Changing Dietary Fat Profiles, Linda Tapsell, Jane O'Shea, Marijka Batterham, Karen Charlton Apr 2013

Dietary Methodology In Clinical Trials: Changing Dietary Fat Profiles, Linda Tapsell, Jane O'Shea, Marijka Batterham, Karen Charlton

Karen E. Charlton

No abstract provided.


Fibre: Male Participants Not Getting Enough, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Linda Tapsell, Marijka Batterham, Karen Charlton Apr 2013

Fibre: Male Participants Not Getting Enough, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Linda Tapsell, Marijka Batterham, Karen Charlton

Karen E. Charlton

A regular intake of dietary fibre has been associated with a number of health benefits. Consuming a high fibre diet may significantly lower the risk of developing heart disease, stroke, hypertension, diabetes and obesity (Anderson et al, 2009). Foods high in fibre such as fruit, vegetables, legumes and wholegrains are regularly included in diets targeting weight loss as they are low in fat, sugar and salt and contain a number of vitamins and minerals. Participants in trials using healthy background diets may increase their fibre intake in addition to the study variables. The aim of this study was to report …


Urinary Sodium Excretion, Dietary Sources Of Sodium Intake And Knowledge And Practices Around Salt Use In A Group Of Healthy Australian Women, Karen Charlton, Heather Yeatman, Fiona Houweling, Sophie Guenon Apr 2013

Urinary Sodium Excretion, Dietary Sources Of Sodium Intake And Knowledge And Practices Around Salt Use In A Group Of Healthy Australian Women, Karen Charlton, Heather Yeatman, Fiona Houweling, Sophie Guenon

Karen E. Charlton

Objective: Strategies that aim to facilitate reduction of the salt content of foods in Australia are hampered by sparse and outdated data on habitual salt intakes. This study assessed habitual sodium intake through urinary excretion analyses, and identified food sources of dietary sodium, as well as knowledge and practices related to salt use in healthy women. Methods: Cross-sectional, convenient sample of 76 women aged 20 to 55 years, Wollongong, NSW. Data included a 24 hour urine sample, three-day food diary and a self-administered questionnaire. Results: Mean Na excretion equated to a NaCl (salt) intake of 6.41 (SD=2.61) g/day; 43% had …


Start Date May Predict Attrition 6 Months Into A 12mth Dietary Intervention Weight Loss Trial, Jane O'Shea, Linda Tapsell, Marijka Batterham, Karen Charlton, Yasmine Probst, Rebecca Thorne, Qingsheng Zhang, Holley Jones Apr 2013

Start Date May Predict Attrition 6 Months Into A 12mth Dietary Intervention Weight Loss Trial, Jane O'Shea, Linda Tapsell, Marijka Batterham, Karen Charlton, Yasmine Probst, Rebecca Thorne, Qingsheng Zhang, Holley Jones

Karen E. Charlton

Participant recruitment is a difficult and time consuming aspect of clinical trials, often resulting in delays and budget overruns. Having reached recruitment targets the next challenge is participant retention. Some weight-loss studies have attrition rates around 60% which may introduce bias in the results. It may be possible to reduce attrition rates if known predictors can be found but to date few studies produced consistent results. The aim of this exploratory study was to determine whether start date could be a predictor of attrition for participants involved in the SMART weight loss clinical trial (ACTRN12608000425392). Recruitment for the trial occurred …


Associations Between Baseline Erythrocyte N-3 Polyunsaturated Fatty Acids And Weight Indices In Volunteers For A Weight Loss Dietary Intervention, Linda Tapsell, J O'Shea, M Batterham, K Charlton, E Warensjo, R Thorne, K Zhang Apr 2013

Associations Between Baseline Erythrocyte N-3 Polyunsaturated Fatty Acids And Weight Indices In Volunteers For A Weight Loss Dietary Intervention, Linda Tapsell, J O'Shea, M Batterham, K Charlton, E Warensjo, R Thorne, K Zhang

Karen E. Charlton

No abstract provided.


Blood Pressure Is Associated With Markers Of Endogenous Fat Metabolism, K Charlton, E Warensjo, Linda Tapsell, M Batterham, J O'Shea Apr 2013

Blood Pressure Is Associated With Markers Of Endogenous Fat Metabolism, K Charlton, E Warensjo, Linda Tapsell, M Batterham, J O'Shea

Karen E. Charlton

No abstract provided.


Pork, Beef And Chicken Have Similar Effects On Acute Satiety And Hormonal Markers Of Appetite, Karen Charlton, Linda Tapsell, Marijka Batterham, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Eleanor Beck Apr 2013

Pork, Beef And Chicken Have Similar Effects On Acute Satiety And Hormonal Markers Of Appetite, Karen Charlton, Linda Tapsell, Marijka Batterham, Rebecca Thorne, Jane O'Shea, Qingsheng Zhang, Eleanor Beck

Karen E. Charlton

The effects of three different meat-containing breakfast meals (pork, beef or chicken) on acute satiety and appetite regulatory hormones were compared using a within-subjects study design. Thirty fasting non-smoking pre-menopausal women attended a research centre on three test days to consume, a meat-containing meal matched in energy (kJ) and protein content, palatability, and appearance. No difference was found between meat groups for either energy intake or macronutrient profile of food consume data subsequent ad libitum buffet lunch, or over the rest of the day. Visual Analogue Scale(VAS) ratings for hunger and satiety over an 180min period did not differ between …


Food And Nutrition Knowledge During Pregnancy - Absence And Opportunity, Heather Yeatman, Dolly Bondarianzadeh, Karen Charlton, Deanne Condon-Paoloni, Luke Gemming, Danka Sinikovic, Barbara Meyer Apr 2013

Food And Nutrition Knowledge During Pregnancy - Absence And Opportunity, Heather Yeatman, Dolly Bondarianzadeh, Karen Charlton, Deanne Condon-Paoloni, Luke Gemming, Danka Sinikovic, Barbara Meyer

Karen E. Charlton

No abstract provided.


Optically Stimulated Luminescence (Osl) Dating Of Perenially Frozen Deposits In North-Central Siberia: Osl Characteristics Of Quartz Grains And Methodological Considerations Regarding Their Suitability For Dating, Lee Arnold, Richard Roberts Mar 2013

Optically Stimulated Luminescence (Osl) Dating Of Perenially Frozen Deposits In North-Central Siberia: Osl Characteristics Of Quartz Grains And Methodological Considerations Regarding Their Suitability For Dating, Lee Arnold, Richard Roberts

Richard G Roberts

Optically stimulated luminescence (OSL) dating of coarse-grained quartz is increasingly being used as the main chronological tool in late Quaternary palaeoenvironmental reconstructions of Siberia. However, relatively little information has been published on the suitability of OSL dating for the various types of perennially frozen sediments found in this region. Here we provide a systematic examination of the quartz luminescence characteristics of 21 perennially frozen samples from the Taimyr Peninsula and adjacent coastal lowlands of north-central Siberia, and discuss their implications for the reliability of single-grain and multi-grain OSL chronologies in such contexts. The results of this study suggest that the …


Development Of The Sar Tt-Osl Procedure For Dating Middle Pleistocene Dune And Shallow Marine Deposits Along The Southern Cape Coast Of South Africa, Zenobia Jacobs, Richard Roberts, Terry Lachlan, Panagiotis Karkanas, Curtis Marean, David Roberts Mar 2013

Development Of The Sar Tt-Osl Procedure For Dating Middle Pleistocene Dune And Shallow Marine Deposits Along The Southern Cape Coast Of South Africa, Zenobia Jacobs, Richard Roberts, Terry Lachlan, Panagiotis Karkanas, Curtis Marean, David Roberts

Richard G Roberts

Optically stimulated luminescence (OSL) dating is now commonly used to estimate the depositional age of Quaternary landforms along the southern Cape coast of South Africa. Due to the early onset of dose saturation in the quartz-rich sediments from this region, determining the age of deposits much older than the last three glacio-eustatic sea-level high stands has been a challenge. In this study, we explored the feasibility of using the thermally-transferred OSL (TT-OSL) dating method to obtain ages for aeolian and shallow marine deposits at three different localities that hold promise to further illuminate the long and complex Late Quaternary sea-level …


Middle Paleolithic Occupation On A Marine Isotope Stage 5 Lakeshore In The Nefud Desert, Saudi Arabia, Michael Petraglia, Abdullah Alsharekh, Remy Crassard, Nick Drake, Huw Groucutt, Adrian Parker, Richard Roberts Mar 2013

Middle Paleolithic Occupation On A Marine Isotope Stage 5 Lakeshore In The Nefud Desert, Saudi Arabia, Michael Petraglia, Abdullah Alsharekh, Remy Crassard, Nick Drake, Huw Groucutt, Adrian Parker, Richard Roberts

Richard G Roberts

No abstract provided.


Dirt, Dates And Dna:Osl And Radiocarbon Chronologies Of Perenially Frozen Sediments In Siberia, And Their Implications For Sedimentary Ancient Dna Studies, Lee Arnold, Richard Roberts, Ross Macphee, James Haile, Fiona Brock, Per Moller, Duane Froese, Alexei Tikhonov, Allan Chivas, M. Thomas Gilbert, Eske Willerslev Mar 2013

Dirt, Dates And Dna:Osl And Radiocarbon Chronologies Of Perenially Frozen Sediments In Siberia, And Their Implications For Sedimentary Ancient Dna Studies, Lee Arnold, Richard Roberts, Ross Macphee, James Haile, Fiona Brock, Per Moller, Duane Froese, Alexei Tikhonov, Allan Chivas, M. Thomas Gilbert, Eske Willerslev

Richard G Roberts

The sedimentary ancient DNA (sedaDNA) technique offers a potentially invaluable means of investigating species evolution and extinction dynamics in high-latitude environments. An implicit assumption of the sedaDNA approach is that the extracted DNA is autochthonous with the host deposit and that it has not been physically transported from older source deposits or reworked within the sedimentary profile by postdepositional mixing. In this paper we investigate whether these fundamental conditions are upheld at seven perennially frozen wetland sites across the Taimyr Peninsula and coastal lowlands of north-central Siberia. Optically stimulated luminescence (OSL) and radiocarbon (14C) dating are used to constrain the …


Late Acheulean Hominins At The Marine Isotope Stage 6/5e Transition In North-Central India, Michael Haslam, Richard Roberts, Ceri Shipton, J Pal, Jacqueline Fenwick, Peter Ditchfield, Nicole Boivin, A Dubey, M Gupta, Michael Petraglia Mar 2013

Late Acheulean Hominins At The Marine Isotope Stage 6/5e Transition In North-Central India, Michael Haslam, Richard Roberts, Ceri Shipton, J Pal, Jacqueline Fenwick, Peter Ditchfield, Nicole Boivin, A Dubey, M Gupta, Michael Petraglia

Richard G Roberts

Single-grain optically stimulated luminescence dating was applied to Late Quaternary sediments at two sites in the Middle Son Valley, Madhya Pradesh, India. Designated Bamburi 1 and Patpara, thesse sites contain Late Acheulean stone tool assemblages, which we associate with non-modern hominins. Age determinations of 140-120. ka place the formation of these sites at around the Marine Oxygen Isotope Stage 6-5 transition, placing them among the youngest Acheulean sites in the world. We present here the geochronology and sedimentological setting of these sites, and consider potential implications of Late Pleistocene archaic habitation in north-central India for the initial dispersal of modern …


Mapping Same-Sex Couple Family Households In Australia, Andrew Gorman-Murray, Christopher Brennan-Horley, Kirsten Mclean, Gordon Waitt, Christopher Gibson Jan 2013

Mapping Same-Sex Couple Family Households In Australia, Andrew Gorman-Murray, Christopher Brennan-Horley, Kirsten Mclean, Gordon Waitt, Christopher Gibson

Christopher R Brennan-Horley

The map (1:1,218,987) accompanying this report is the first to depict the distribution of same-sex couple family households across Australia. The map and the report contribute to emerging scholarship combining critical geographies of sexualities with quantitative techniques and GIS in order to advance the political claims of sexual minorities. The data were collected through the 2006 Census and obtained via consultation with the Australian Bureau of Statistics. These data included the number of same-sex couple family households for all Statistical Divisions across Australia and for Statistical Sub-Divisions within metropolitan capital cities. Geographical concentrations of same-sex couple family households were determined …