Life Sciences Commons^™

Crowdfunding For Biotechs: How The Sec’S Proposed Rule May Undermine Capital Formation For Startups, Brian J. Farnkoff

Journal of Contemporary Health Law & Policy (1985-2015)

No abstract provided.

The Effects Of Nesting Environment On Neonatal Hypoxic-Ischemic Injury, Laura Grace Rollins

Graduate Masters Theses

Term neonates with hypoxic-ischemic (HI) injury are at risk for devastating neurological sequelae. The objective of this study is to determine if altering the early environment for maternal care-taking impacts the immediate and long-term sequelae of HI offspring. The Rice-Vannucci model was used to induce HI in postnatal day (PND) 7 Long-Evans pups. Litters were assigned to a closed nest (CN) or normal standard housing (SH) condition. Neurobehavioral development, cognitive ability, and stress response were assessed to establish any benefits of the CN condition. Finally, postmortem brain tissue was analyzed for morphometric markers of injury.

Spatial Analysis Of Factors Influencing Long-Term Stress In The Grizzly Bear (Ursus Arctos) Population Of Alberta, Canada, Mathieu Bourbonnais, Trisalyn Nelson, Mark Cattet, Chris T. Darimont, Gordon Stenhouse

Physiology Collection

Non-invasive measures for assessing long-term stress in free ranging mammals are an increasingly important approach for understanding physiological responses to landscape conditions. Using a spatially and temporally expansive dataset of hair cortisol concentrations (HCC) generated from a threatened grizzly bear (Ursus arctos) population in Alberta, Canada, we quantified how variables representing habitat conditions and anthropogenic disturbance impact long-term stress in grizzly bears. We characterized spatial variability in male and female HCC point data using kernel density estimation and quantified variable influence on spatial patterns of male and female HCC stress surfaces using random forests. Separate models were developed for regions …

The Effects Of Chronic Simvastatin Treatment On The Expression Of Behavioral Symptoms In A Transgenic Mouse Model Of Huntington’S Disease, Ashley Whitmarsh

University of New Orleans Theses and Dissertations

Huntington’s disease (HD) is a heritable, neurodegenerative disorder characterized by motor, cognitive, and psychiatric disturbances. An unstable CAG expansion within the gene normally encoding for the Huntingtin protein is responsible. The expanded mutant form of Huntingtin and the putative protein co-factor Rhes interact and cause cell death within the striatum. We hypothesized chronic treatment with simvastatin, a cholesterol lowering drug, would disrupt the biosynthetical pathway which gives both Rhes and its target cells binding sites and render Rhes inactive. Healthy and HD mice were treated with simvastatin or a vehicle. Animals’ motor behavior was assessed with three separate tests over …

Enrichment And Training Improve Cognition In Rats With Cortical Malformations, Kyle R. Jenks, Marcella M. Lucas, Ben A. Duffy, Ashlee A. Robbins, Barjor Gimi, Jeremy M. Barry, Rod C. Scott

Dartmouth Scholarship

Children with malformations of cortical development (MCD) frequently have associated cognitive impairments which reduce quality of life. We hypothesized that cognitive deficits associated with MCD can be improved with environmental manipulation or additional training. The E17 methylazoxymethanol acetate (MAM) exposure model bears many anatomical hallmarks seen in human MCDs as well as similar behavioral and cognitive deficits. We divided control and MAM exposed Sprague-Dawley rats into enriched and non-enriched groups and tested performance in the Morris water maze. Another group similarly divided underwent sociability testing and also underwent Magnetic Resonance Imaging (MRI) scans pre and post enrichment. A third group …

The Fate Of Local Food Systems In The Global Industrialization Market: Food And Social Justice In The Rural South, Wylin D. Wilson, Reuben C. Warren, Stephen O. Sodeke, Norbert Wilson

Professional Agricultural Workers Journal

This paper investigates the connection between local food systems, health disparities, and social justice in the rural South. It begins with the relationship between food insecurity and health disparities that disproportionately affect racial and ethnic minority populations, and non-minority women and children. First, we discuss the concept of health disparities within the context of bioethics and public health ethics in order to explore the link between the food system and health as a social justice issue. Second, we define health disparities and discuss how they have historically plagued and disadvantaged racial minority populations. Third, we examine these disparities within the …

The Impact Of Selected Socioeconomic Factors On Asset Building In Rural Communities, Nii O. Tackie, Judith N. Aboagye, Gwendolyn J. Johnson, Millicent Braxton, Latanya Hunt-Haralson, Gertrude D. Wall

Professional Agricultural Workers Journal

The study examined the impact of selected socioeconomic factors on asset building. Using a questionnaire, data were obtained from a convenience sample of 204 participants from several Alabama Black Belt Counties, and analyzed using descriptive statistics and logit analysis. The results showed that a majority (64%) was willing to participate in an asset building program. Of this, an overwhelming majority (at most 70%) wanted to set up a small business; further their education, or purchase a home. In addition, one socioeconomic factor, age, had a statistically significant (p = 0.016) effect on willingness to participate in an asset building …

Community-University Partnerships For Change In The Black Belt South, Rosalind Harris

Professional Agricultural Workers Journal

This article explores issues related to community-university partnerships by examining

the unfolding of the Black Belt Initiative, a 21^st century mobilization within the Black Belt South to establish a Black Belt Regional Commission. The Black Belt Initiative provides an instructive and compelling case study. For instance, the very nature of the Black Belt Initiative’s beginnings through the provision of a grant by Senator Zell Miller of Georgia to the University of Georgia with the proviso that “poverty – not race be the guiding principle…” heightened the tension between historically black and white universities reflecting longstanding contestations around how problems …

Community Capital And Local Economic Development Efforts, Andrew A. Zekeri

Professional Agricultural Workers Journal

Actions by local groups and leaders constitute an essential but poorly understood element of many rural economic development efforts. Previous studies suggest that local development efforts can influence community changes, but questions remain about why localities differ in economic development efforts. Drawing upon community capital framework and human ecological theory, the purpose of this research was to examine the effects of community capital on economic development efforts in rural communities. Hierarchical regression results indicate that social capital, cultural capital, built capital significantly predict economic development effort to develop recreation and tourism and human services. Despite that, only built capital and …

Plight Of Black Farmers In The Context Of Usda Farm Loan Programs: A Research Agenda For The Future, Shakara S. Tyler, Eddie A. Moore

Professional Agricultural Workers Journal

Black farmers remain an underdeveloped topic in academic literature. This historical study used a historical research methodology to assess the plight of Black farmers in the context of United States Department of Agriculture (USDA) farm loan programs and offered an array of future research recommendations. We investigated the severity of the plight of Black farmers in the context of USDA farm loan programs with an emphasis on effective and responsive leadership in relation to four elements: 1) legislative initiatives, 2) policy initiatives, 3) USDA structure and delivery systems, and the 4) Pigford v. Glickman class action and consent decree. We …

Dog Behavior Co-Varies With Height, Bodyweight And Skull Shape, Paul D. Mcgreevy, Dana Georgevsky, Johanna Carrasco, Michael Valenzuela, Deborah L. Duffy, James A. Serpell

Eidonomy Collection

Dogs offer unique opportunities to study correlations between morphology and behavior because skull shapes and body shape are so diverse among breeds. Several studies have shown relationships between canine cephalic index (CI: the ratio of skull width to skull length) and neural architecture. Data on the CI of adult, show-quality dogs (six males and six females) were sourced in Australia along with existing data on the breeds’ height, bodyweight and related to data on 36 behavioral traits of companion dogs (n = 8,301) of various common breeds (n = 49) collected internationally using the Canine Behavioral Assessment and Research Questionnaire …

Land Grabs And Implications On Food Sovereignty And Social Justice In Senegal, Joanna Lafrancesca

Master's Theses

This thesis focuses on the case study of Senegal to examine the implications of large- scale land acquisitions on the livelihoods of small-scale farmers. I investigate the diverse perspectives of market enthusiasts, human rights organizations, peasants, the state, and international financial organizations on large-scale land acquisitions. Based on primary research, I argue that the state of Senegal plays an active role in permitting “land grabs” and that they pose a threat to food sovereignty among Senegalese host communities. Lastly, I argue there needs to be a broader understanding of long-term consequences and risks to insure social justice in areas affected …

Evolution And Functional Morphology Of The Cephalic Lobes In Batoids, Samantha Lynn Mulvany

USF Tampa Graduate Theses and Dissertations

Cephalic lobes are unique structures derived from the anterior pectoral fins, found in select myliobatid stingrays. Many benthic batoids utilize undulatory locomotion and use their pectoral fins for both locomotion and prey capture. Pelagic myliobatids that possess cephalic lobes utilize oscillatory locomotion, using their pectoral fins to locomote and their cephalic lobes for prey capture. Despite differences in habitat usage and locomotor modes, these batoids feed on very similar benthic organisms. The purpose of this study was to 1.) compare the morphology of the cephalic lobes and anterior pectoral fins in lobed and lobeless species, looking at skeletal elements, musculature …

Observing The Unwatchable Through Acceleration Logging Of Animal Behavior, Danielle D. Brown, Roland Kays, Martin Wikelski, Rory Wilson, A. Peter Klimley

Methodology and Animal Models in Research

Behavior is an important mechanism of evolution and it is paid for through energy expenditure. Nevertheless, field biologists can rarely observe animals for more than a fraction of their daily activities and attempts to quantify behavior for modeling ecological processes often exclude cryptic yet important behavioral events. Over the past few years, an explosion of research on remote monitoring of animal behavior using acceleration sensors has smashed the decades-old limits of observational studies. Animal-attached accelerometers measure the change in velocity of the body over time and can quantify fine-scale movements and body postures unlimited by visibility, observer bias, or the …

Environmental And Socio-Economic Considerations For Aquaculture In Jervis Bay, Nsw, Alyssa Joyce, Ana M. Rubio, Pia C. Winberg

Dr Pia C Winberg

No abstract provided.

The Cost Of Affordable Food, Candice L. Cobuzzi

SURGE

When someone puts a piece of food in front of me, I don’t just see a piece of food.

Instead, I see an innocent cow being cornered by a forklift and slaughtered, its limp, moist tissue hung on a long conveyer belt with hundreds of others.

I see hundreds of chemically-injected chickens packed into a dark barn with no hope of seeing sunlight in their lifetime.

I see immigrants pulled from their houses like criminals, taken away from the lives they’ve spent years building for themselves and their families, working for the same food company that courted them into the …

Managing The Veterinary Clinic Enterprise, Shelby N. Smyly

Animal Science

This document serves as a guideline for the student management of the Veterinary Clinic Enterprise.

Assessing The Biodiversity And Susceptibility Of Trees In Maxwell Park To Future Invasive Tree Pest Outbreaks, Genevieve Alexander '14

Outstanding Senior Seminar Papers

The purpose of this project was to assess tree susceptibility to invasive tree pest outbreaks in a Central-Illinois urban park. Tree biodiversity in Maxwell Park, located in the Town of Normal, Illinois, was evaluated assuming that the greater the tree biodiversity in a park, the more resilient the park would be to future invasive tree pest outbreaks. The Town of Normal Parks and Recreation Department served as the community partner for this project. By determining Maxwell Park’s current level of biodiversity, proposed new trees for future replacement plantings could be identified to help increase biodiversity and decrease the potential for …

Minerva 2013, The Honors College

Minerva

This issue of Minerva includes an article on the opening of Charlie's Terrace in honor of former Honors Dean, Charlie Slavin; a discussion on community engagement in the Honors curriculum and community; an article on the student recipients of the Rezendes Travel Scholarship; and several articles catching up with Honors alumni.

Progression Magazine, 2013 Winter, Coastal Carolina University

Progression Magazine

Magazine of the College of Science at Coastal Carolina University.

West Coast Rock Lobster Harvest Strategy And Control Rules : 2015 – 2019 : A Discussion Paper, Department Of Fisheries

Fisheries management papers

No abstract provided.

Neural Responses During Trace Conditioning With Face And Non-Face Stimuli Recorded With Magnetoencephalography, Nicholas Lee Balderston

Theses and Dissertations

During fear conditioning a subject is presented with an initially innocuous stimulus like an image (conditioned stimulus; CS) that predicts an aversive outcome like a mild electric shock (unconditioned stimulus; UCS). Subjects rapidly learn that the CS predicts the UCS, and show autonomic fear responses (CRs) during the presentation of the CS. When the CS and the UCS coterminate, as is the case for delay conditioning, individuals can acquire CRs even if they are unable to predict the occurrence of the UCS. However when there is a temporal gap between the CS and the UCS, CR expression is typically dependent …

Photo-Identification Methods Reveal Seasonal And Long-Term Site-Fidelity Of Risso’S Dolphins (Grampus Griseus) In Shallow Waters (Cardigan Bay, Wales), Marijke N. De Boer, Josephine Clark, Mardik F. Leopold, Mark P. Simmonds, Peter J.H. Reijnders

Ecology Collection

A photo-identification study on Risso’s dolphins was carried out off Bardsey Island in Wales (July to September, 1997-2007). Their local abundance was estimated using two different analytical techniques: 1) mark-recapture of well-marked dolphins using a “closed-population” model; and 2) a census technique based on the total number of iden-tified individual dolphins sighted over the study period. The mark-recapture estimates of 121 (left sides; 64 - 178, 95% CI; CV 0.24) and 145 dolphins (right sides; 78 - 213, 95% CI; CV 0.24) closely matched the census technique estimates (population size of 90 - 151). It was found that the dolphins …

Longevity And Mortality Of Owned Dogs In England, D. G. O'Neill, D. B. Church, P. D. Mcgreevy, P. C. Thomson, D. C. Brodbelt

Epidemiology Collection

Improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity. Epidemiological research using electronic patient records (EPRs) collected from primary veterinary practices overcomes many inherent limitations of referral clinic, owner questionnaire and pet insurance data. Clinical health data from 102,609 owned dogs attending first opinion veterinary practices (n = 86) in central and southeast England were analysed, focusing on 5095 confirmed deaths.

Of deceased dogs with information available, 3961 (77.9%) were purebred, 2386 (47.0%) were female, 2528 (49.8%) were neutered and 1105 (21.7%) were insured. The overall median longevity was 12.0 years …

Research: South Dakota State University, Winter 2013, Christie Delfanian, Matt Landwehr

Research: South Dakota State University

CONTENTS:

South Dakota expertise integral part of Landsat [Page] 1
West Nile: Researchers help public health officials combat West Nile virus [page] 2
Health care: arteries, corticosteroids, concussions, and preemies [Page] 4
Oilseeds [Page] 6
Undergraduate Research [Page] 8
Organ donation key to helping Native Americans on dialysis [Page] 10
Researchers meet challenge of increased competition: 2012 measurements [Page] 11

Ogden College Of Science & Engineering Newsletter (Winter 2013), Cheryl Stevens, Dean

Ogden College of Science & Engineering Publications

No abstract provided.

Connecting The Dots: Understanding Migration In The Context Of Other Periods Of The Annual Cycle, Kristina Lee Paxton

Dissertations

Migration is a fundamental characteristic of the life history of many organisms. Large-scale seasonal movements expose migratory species to an array of differing environmental conditions such that the ecology, behavior, and life history strategies of migratory species must balance selection pressures associated with each phase of the annual cycle. Therefore, scientists increasingly realize that to understand the ecology of a migratory species in any one phase of the annual cycle requires an understanding of how other phases may interact with and influence the period of interest. That said, following individuals throughout the year poses a serious challenge.

The focus of …

The Role Of The Amygdala, Retrosplenial Cortex, And Medial Prefrontal Cortex In Trace Fear Extinction And Reconsolidation, Janine Lynn Kwapis

Theses and Dissertations

A wealth of research has outlined the neural circuits responsible for the consolidation, reconsolidation, and extinction of standard "delay" fear conditioning, in which awareness is not required for learning. Far less is understood about the neural circuit supporting more complex, explicit associations. "Trace" fear conditioning is considered to be a rodent model of explicit fear because it relies on the cortex and hippocampus and requires explicit contingency awareness in humans for successful acquisition. In the current set of studies, we aimed to better characterize the neural circuit supporting the consolidation, reconsolidation, and extinction of trace fear in order to better …

Iptakalim Attenuates Self-Administration And Acquired Goal-Tracking Behavior Controlled By Nicotine, S. Charntikov, N. Swalve, Steven T. Pittenger, K. Fink, S. Schepers, G. C. Hadlock, A. E. Fleckenstein, G. Hu, Ming Li, Rick A. Bevins

Department of Psychology: Faculty Publications

Iptakalim is an ATP-sensitive potassium channel opener, as well as an a4b2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Pretreatment with iptakalim diminishes nicotine-induced dopamine (DA) and glutamate release in the nucleus accumbens. This neuropharmacological profile suggests that iptakalim may be useful for treatment of nicotine dependence. Thus, we examined the effects of iptakalim in two preclinical models. First, the impact of iptakalim on the interoceptive stimulus effect of nicotine was evaluated by training rats in a discriminated goal-tracking task that included intermixed nicotine (0.4 mg/kg, SC) and saline sessions. Sucrose was intermittently presented in a responseindependent manner only on nicotine sessions. …

Landings, Vol. 21, No. 12, Maine Lobstermen’S Community Alliance

Landings: News & Views from Maine's Lobstering Community

Landings content emphasizes science, history, resource sustainability, economic development, and human interest stories related to

Maine’s lobster industry. The newsletter emphasizes lobstering as a traditional, majority-European American lifeway with an economic and social heritage unique to the coast of Maine. The publication focuses how ongoing research to engage in sustainable, non-harmful, and non-wasteful commercial fishing practices benefit both the fishery and Maine's coastal legacy.

Maine Lobstermen’s Community Alliance (MLCA) started publication of Landings, a 24-page newsletter in January 2013 as the successor of the Maine Lobstermen’s Association (MLA) Newsletter. As of 2022, the MLCA published over 6,500 copies of …