Life Sciences Commons^™

Cross-Sector Review Of Drivers And Available 3rs Approaches For Acute Systemic Toxicity Testing, Troy Seidle, Sally Robinson, Tom Holmes, Stuart Creton, Pilar Prieto, Julia Scheel, Magda Chlebus

Troy Seidle, PhD

Acute systemic toxicity studies are carried out in many sectors in which synthetic chemicals are manufactured or used and are among the most criticized of all toxicology tests on both scientific and ethical grounds. A review of the drivers for acute toxicity testing within the pharmaceutical industry led to a paradigm shift whereby in vivo acute toxicity data are no longer routinely required in advance of human clinical trials. Based on this experience, the following review was undertaken to identify (1) regulatory and scientific drivers for acute toxicity testing in other industrial sectors, (2) activities aimed at replacing, reducing, or …

Humane Society International’S Global Campaign To End Animal Testing, Troy Seidle

Troy Seidle, PhD

The Research & Toxicology Department of Humane Society International (HSI) operates a multifaceted and science-driven global programme aimed at ending the use of animals in toxicity testing and research. The key strategic objectives include: a) ending cosmetics animal testing worldwide, via the multinational Be Cruelty-Free campaign; b) achieving near-term reductions in animal testing requirements through revision of product sector regulations; and c) advancing humane science by exposing failing animal models of human disease and shifting science funding toward human biology-based research and testing tools fit for the 21st century. HSI was instrumental in ensuring the implementation of the March 2013 …

The Three Rs: The Way Forward, Michael Balls, Alan M. Goldberg, Julia H. Fentem, Caren L. Broadhead, Rex L. Burch, Michael F.W. Festing, John M. Frazier, Coenraad F.M. Hendriksen, Margaret Jennings, Margot D.O. Van Der Kamp, David B. Morton, Andrew N. Rowan, Claire Russell, William M.S. Russell, Horst Spielmann, Martin Stephens, William S. Stokes, Donald W. Straughan, James D. Yager, Joanne Zurlo, Bert F.M. Van Zutphen

Andrew N. Rowan, DPhil

This is the report of the eleventh of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM), which was established in 1991 by the European Commission. ECVAM's main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scientific and regulatory acceptance of alternative methods which are of importance to the biosciences and which reduce, refine or replace the use of laboratory animals. One of the first priorities set by ECVAM was the implementation of procedures which would enable it to become well-informed about the state-of-the-art of non-animal test …

Wellness And Food Preferences Among Children Of Latino Immigrant Families In The Arcadia Community Of Spartanburg County, Sarah Grace Keaveny

Student Scholarship

The topic of this capstone is the result of my synthesis across disciplines. As a student with majors in Biology and Spanish with a concentration in Medical Humanities, I wanted to research a topic that would include my disciplines in a way that would meaningfully prepare me to leave my undergraduate years for medical school. This project seeks to generate an understanding of the culturally created eating habits and perceptions of wellness in Latino children living in the Arcadia Community, as told by their mothers. By seeking this understanding, I hope that this project may serve as a tool to …

A Movement Tool Kit For The Divergent And Convergent Cps Guidelines: Instruction Cards And Activity Floor Mats, Adela Vangelisti

Creativity and Change Leadership Graduate Student Master's Projects

A Movement Tool Kit for the Divergent and Convergent CPS Guidelines:

Instruction Cards and Activity Floor Mats

Movement is as natural to humans as breathing is, and, yet, passivity starts early in schools. We are taught to sit still and in silence for long periods of time. By the time we reach adulthood and enter the workforce, we have almost forgotten our sense of embodiment. This lack of movement is counter-productive, not only to learning but to the development of creativity as well. For this project, I designed a tool to recapture the joy and playfulness of movement. Furthermore, the …

Sustainable Mountain Tourism: An Analysis Of Bosnia- Herzegovina’S Wine Tourism And Its Future, John Hudelson

All Faculty Scholarship for the College of the Sciences

Bosnia-Herzegovina (B-H) remains one of the most underdeveloped countries on the European Continent yet it holds great potential as a tourist destination for outdoor adventurers, history enthusiasts, and now, wine connoisseurs. The southern part of this merged nation has always been an area of wine production, but the industry has been slow to develop into a net exporter of its wines. The author and many of the industry’s supporters believe that it would be more lucrative to follow in the footsteps of its western neighbor, Croatia, and develop the wine industry through wine tourism. Utilizing historical data, interviews, analysis of …

A Vision Becoming Reality, Gill Langley

Gill Langley, PhD

Non-animal science in toxicology and health research has been progressing for decades, but only now is it being seen widely as advanced science. The emergence of novel human biology-based tools and models, combined with legislative and regulatory change, a 21st century concept for toxicology, continuing failures in the drug pipeline, and systematic critiques of animal models, have created a pivotal moment of change. The leading edge is starting to become the norm. Humans and other animals are likely to benefit as a result.

Place Events Fall 2014, Place

PLACE Historical Documents

This document describes PLACE events at Linfield College for fall 2014.

Parental Factors That Influence Swimming In Children And Adolescents, Jennifer Pharr, Carol C. Irwin, Richard L. Irwin

Environmental & Occupational Health Faculty Publications

Swimming can be an important source of physical activity across the life-span. Researchers have found that parents influence physical activity behaviors of their children. The purpose of this study was to determine what parental factors influenced the number of days that children swam. Survey respondents (n = 1,909) from six cities across the United States were surveyed at local YMCAs. Children were found to swim significantly more if their parents encouraged them to swim, members of the family knew how to swim and swam with them, or their parents were not afraid of the children drowning or afraid of …

The Ecology Of Infancy And Early Childhood In Rural Senegal; A Five Year Old Can Boot But Not Foot, An Exploration Of Where Biology Meets Culture, Heather Mills

Independent Study Project (ISP) Collection

This research project explores the life stages of infancy and early childhood in the village of Ndiane in the Thies region of Senegal. I will discuss how biology meets culture to influence children, parenting styles, and expectations of the life stage. How does ecology, the interaction of physical, biological and cultural landscapes, characterize childhood and the intertwined belief systems that influence parenting? The information was gathered using a combination of participant observation and free list interviews.

Rough Hands: Family Conceptions Of Rural Morocco’S Agricultural Labor, A Case Study, Leah Kahler

Independent Study Project (ISP) Collection

Conceptions of success for people in any capitalist context are tangled with social hierarchies of work. The rural women of Morocco have been specifically singled out as the objects discourses about their domestic and agricultural work, agency, gender identity and role, and their use of private and public space ownership. This project will examine the justifications, conceptions, and satisfaction with rural-agricultural work in a small-scale family farm in Morocco’s Al Hoceima province. Using the case study approach, I will live with a family in Sidi Bouafif and work alongside the family for an eight-day fieldwork period. Through participant observation and …

Using The Minority Stress Model To Understand Depression In Lesbian, Gay, Bisexual, And Transgender Individuals In Nebraska, Molly Mccarthy, Christopher M. Fisher, Jay A. Irwin, Jason D. Coleman, Aja D. Kneip Pelster

Sociology and Anthropology Faculty Publications

Previous studies demonstrated the utility of the minority stress model in understanding health disparities for lesbian, gay, bisexual, and transgender (LGBT) populations. Since most research has considered large metropolitan areas, predominantly in coastal regions of the United States, this research focuses on a midwestern state, Nebraska. This study sought to assess the relationships between depressive symptoms experienced by participants (N = 770) and minority stress variables, including experiences with violence, perceptions of discrimination, and respondents’ degree of self-acceptance of their LGBT identity. Regression analysis revealed that after controlling for demographic variables, self-acceptance, and perceived discrimination were correlated with depressive symptoms. …

Hsisp Annotated Bibliography: Moral & Character Education (1998-2013), Erich Yahner

Erich Yahner

No abstract provided.

Food Insecurity And Psychological Well-Being Among Women Living With Hiv/Aids On Antiretroviral Therapy In The Alabama Black Belt, Andrew A. Zekeri, Youssouf Diabate

Professional Agricultural Workers Journal

The objective of this research was to estimate the prevalence of food insecurity and determine if food insecurity is associated with psychological well-being among women living with HIV/AIDS. Survey data were collected from 268 women living with HIV/AIDS attending two clinics that provide medical and social support services to HIV-positive patients who live in 23 counties in Southeast Alabama. The results indicated that, using USDA food security scale, 54% of the women were food insecure. Multiple regression analysis results indicated that income, depressive symptoms, race, and participation in SNAP were significant predictors of food insecurity; employment and education were not …

A Federal Commission For The Black Belt South, Ronald C. Wimberley, Libby V. Morris, Rosalind Harris

Professional Agricultural Workers Journal

Recent legislation by the U.S. Congress authorized a federal regional commission for the Black Belt South. Three southern social scientists first proposed the commission at Tuskegee University’s Professional Agricultural Workers Conference in 1990. Following congressional seminars on the Black Belt by Ronald Wimberley and Libby Morris, the first legislation for the commission was introduced in the U.S. House of Representatives in 1994. After a succession of 12 U.S. House and Senate Bills, Congress finally authorized “the Southeast Crescent Regional Commission” in 2008 with support by various, and sometimes competing, groups. This paper traces and updates the chronology of sociological research, …

Organic Growers Of Alabama Cooperative, A Loosely Fitted Cooperative: Nurturing The Community And Growing Together, Wylin D. Wilson, Jose Gbadamosi, Decetti Taylor, Susan Barnes, Jan Garrett, Asabi Hunter, Cheryl Parker, Wendy Williams, Henry Williams

Professional Agricultural Workers Journal

The age-old connection between the people and the land is something that seven women, who have organized themselves into a loosely fitted cooperative, are reviving. In the process of growing together as members of a cooperative, these women in Macon County, Alabama, are not only promoting healthy living and nurturing community, but are also addressing the issue of food security by making nutritious affordable produce and other agricultural products available to their community. Additionally, they are illustrating alternative strategies of community and economic development. This article examines why they chose the structure of a loosely fitted cooperative over a traditional …

How Do We Know? Paths To Wisdom, Place

PLACE Historical Documents

This document explains the PLACE theme at Linfield College for 2014-2015 (How Do We Know? Paths to Wisdom).

Paternal Incarceration And Children's Food Insecurity: A Consideration Of Variation And Mechanisms, Kristen Turney

University of Kentucky Center for Poverty Research Discussion Paper Series

Despite growing attention to the unintended consequences of paternal incarceration for children’s wellbeing across the life course, little is known about whether and how paternal incarceration is related to food insecurity among children, an especially acute and severe form of deprivation. In this article, I use data from the Fragile Families and Child Wellbeing Study, a cohort of children born to mostly unmarried mothers, to examine the relationship between paternal incarceration and three indicators of food insecurity among young children: current food insecurity (at age five), onset of food insecurity (between ages three and five), and exit from food insecurity …

Management Regimes And Its Impact On The Wetland Fisheries Management In Assam, Ganesh Chandra

Ganesh Chandra

Assam is endowed with copious aquatic wealth in the form of beels, swamps, ponds and rivers. The floodplain wetlands (beels) extending over one lakh hectare, constitute the most important fishery resource of the state. The beels are considered as one of the most productive ecosystems owing to their characteristic interactions between land and water system. These wetlands are the common property resource and under different management regimes. These wetlands are under various management regimes, i.e., private management (individuals and groups), fishermen cooperative management, Community-based fisheries management (decentralized management, Government works as facilitator) and open access. Most of the unregistered beels …

Balance And Power In Older Adults With And Without A History Of Falls, Stephanie Michelle Gray

Graduate Theses and Dissertations

The purpose of this study was to observe the differences between power and balance in older adults over the age of 65 with and without falls. A total of 62 community dwelling older adults between the ages of 65 and 92 participated in the study. Two groups consisted of 25 fallers and 37 non-fallers. No statistical differences were found between groups on age, height, weight, or BMI. Testing included the Berg Balance Scale (BBS) to test balance, the Tendo Weightlifting Analyzer (TWA) during a sit-to-stand to test lower body power, and the Physical Activity Scale for the Elderly (PASE) to …

Academic Clustering Of Student-Athletes: A Case Study Of Football And Basketball Programs, Matthew Brett Rowland

Graduate Theses and Dissertations

This study explores the topic of academic clustering within the football and men's and women's basketball teams at the University of Arkansas. Given the prominence of collegiate sport in America, this paper examines a relatively understudied topic regarding student-athletes and education. Using a mixed methods approach, the topic of academic clustering is analyzed statistically, as well as through in-depth interviews with student-athletes and academic advisors in the athletic department. Statistical analysis shows significant over- and under-representation of student-athletes in certain University colleges (e.g., Fulbright College of Arts and Sciences, Walton College of Business, and College of Engineering), the presence of …

The Association Of Wellness Policy Quality And Percentage Of Obesity In Schools, Bryce M. Abbey

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Schools possess a unique opportunity to reach a large captive audience and are becoming one of the battlegrounds for childhood obesity. To address the school environment’s role on the influence of American children’s nutritional intake and participation in physical activity, the United States (US) Federal Government adopted the Healthy, Hunger-Free Kids Act of 2010, placing an emphasis on implementation of the local school wellness policy (LSW). The purpose of this study was to examine the association between LSW and percentage of obesity in school districts within Nebraska. Aggregate district-wide body mass index (BMI) percentile data were utilized from previously collected …

Exploring Germplasm Diversity To Understand The Domestication Process In Cicer Spp. Using Snp And Dart Markers, Manish Roorkiwal, Eric J. Von Wettberg, Hari D. Upadhyaya, Emily Warschefsky, Abhishek Rathore, Rajeev K. Varshney

College of Agriculture and Life Sciences Faculty Publications

To estimate genetic diversity within and between 10 interfertile Cicer species (94 genotypes) from the primary, secondary and tertiary gene pool, we analysed 5,257 DArT markers and 651 KASPar SNP markers. Based on successful allele calling in the tertiary gene pool, 2,763 DArT and 624 SNP markers that are polymorphic between genotypes from the gene pools were analyzed further. STRUCTURE analyses were consistent with 3 cultivated populations, representing kabuli, desi and pea-shaped seed types, with substantial admixture among these groups, while two wild populations were observed using DArT markers. AMOVA was used to partition variance among hierarchical sets of landraces …

Can Anyone With Low Income Be Food Secure?: Mitigating Food Insecurity Among Low Income Households With Children In The Tampa Bay Area, Edgar Allan Amador

USF Tampa Graduate Theses and Dissertations

In the US over the last few years, approximately 14.5% of households experience food insecurity at some point throughout the year. While studies on food insecurity in the US have determined that household income and specifically income available to spend on food is of critical importance to food security, it is still unclear why some households with low income are able to maintain food security while others experience food insecurity in a pattern characterized as not constant but recurrent. This dissertation compares households with children at different levels of food security and insecurity using the USDA Core Food Security Module …

Considering Sport Participation As A Source For Physical Activity Among Adolescents, Jennifer Pharr, Nancy L. Lough

Environmental & Occupational Health Faculty Publications

BACKGROUND:

Studies have shown participation in sport is lower among girls than boys, decreases as students matriculate through high school, is lowest among Black and Hispanic girls and has a positive relationship with SES. With sport recognized as a contributor to physical activity and health in adolescents, consideration of diminishing rates of participation appears warranted. The purpose of this study was to identify patterns related to differences in self-reported sport participation between genders, ethnic groups, grades and SES.

METHODS:

This study was a cross-sectional, secondary analysis of data collected for a sport interest survey. All students in grades 8-11 attending …

Across-Year Social Stability Shapes Network Structure In Wintering Migrant Sparrows, Daizaburo Shizuka, Alexis S. Chaine, Jennifer Anderson, Oscar Johnson, Inger Marie Laursen, Bruce E. Lyon

School of Biological Sciences: Faculty Publications

Migratory birds often form flocks on their wintering grounds, but important details of social structure such as the patterns of association between individuals are virtually unknown. We analysed networks of co-membership in short-term flocks for wintering golden-crowned sparrows (Zonotrichia atricapilla) across three years and discovered social complexity unsuspected for migratory songbirds. The population was consistently clustered into distinct social communities within a relatively small area (~ 7 ha). Birds returned to the same community across years, with mortality and recruitment leading to some degree of turnover in membership. These spatiotemporal patterns were explained by the combination of space …

Racism And Capitalism: Dual Challenges For The Food Movement, Eric Holt-Giménez

Food Systems Summit 2014

No abstract provided.

Scientists And Animal Research: Dr. Jekyll Or Mr. Hyde?, Andrew N. Rowan

Andrew N. Rowan, DPhil

Why is the public so sensitive about the use of a few tens of millions of animals in research when they do not object to killing hundreds of millions of pigs and cows and billions of chickens for our meat diet? Why is animal research considered so bad despite the public's high opinion of science (and scientists)? Perhaps it is the image of the scientist as an objective and cold individual who deliberately inflicts harm (pain, distress, or death) on his (the public image is usually male) innocent animal victims that arouses so much horror and concern. This paper does …

Laboratory Rodent Welfare: Thinking Outside The Cage, Jonathan P. Balcombe

Jonathan Balcombe, PhD

This commentary presents the case against housing rats and mice in laboratory cages; the commentary bases its case on their sentience, natural history, and the varied detriments of laboratory conditions. The commentary gives 5 arguments to support this position: (a) rats and mice have a high degree of sentience and can suffer, (b) laboratory environments cause suffering, (c) rats and mice in the wild have discrete behavioral needs, (d) rats and mice bred for many generations in the laboratory retain these needs, and (e) these needs are not met in laboratory cages.

An Ecological Approach To Experiential Learning In An Inner-City Context, Pauline Garcia-Reid, Robert Reid, Bradley Forenza

Department of Family Science and Human Development Scholarship and Creative Works

In‐depth, qualitative interviewing was employed to describe processes and competencies experienced by family science interns, who practiced in a high‐risk ecological context. Twenty interns from a 3‐year period were recruited. All had interned on the same federally funded, HIV/substance abuse prevention grant in the same focal city. Within this sample, it was determined that experiential learning—vis‐à‐vis the internship—facilitated both intrapersonal processes and ecological competencies for family science interns, who may otherwise have lacked this knowledge when assuming professional roles. Implications for policy and practice are discussed.