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Full-Text Articles in Life Sciences

Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman Jan 2022

Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman

Honors Theses

Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that affects over 5 million individuals in the United States alone. While AD is primarily thought of as a disease that destroys neural networks required for memory recall and formation, AD also cause impairment in emotional regulation, cognitive flexibility, and executive function pathways. The cause of AD is unknown; however, the allele ApoE4 has been identified as a risk factor for the onset of AD. ApoE4 provides a valuable opportunity to study AD through animal models. This thesis utilized a human ApoE4 transgenic rat model (hApoE4) to investigate the biological and behavioral …


Community Interventions To The Food Insecurity Crisis Inuit Currently Face In Nunangat, Alyssia R. Getschow Jan 2022

Community Interventions To The Food Insecurity Crisis Inuit Currently Face In Nunangat, Alyssia R. Getschow

Honors Theses

Inuit living in Nunangat, a northern territory in Canada, are facing unprecedented rates of food insecurity. The increasing impacts of anthropogenic climate change are rapidly changing the Arctic landscape in Nunangat, posing challenges to Inuit hunters who hunt and live completely self-sufficient off of the land. This lack of access to country foods and the impacts these conditions are having on Inuit communities are forcing Inuit to consider aid propositions from the Canadian government. Due to a long history of conflict with white settlers during the colonization of Canada, there is a feeling of distrust and cultural distaste between Canada …