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Osteoblast Oncostatin M Signaling In Modeled Spaceflight, Jacob Goyden

Boise State University Theses and Dissertations

Bone deterioration is a challenge in long-term spaceflight with significant connections to terrestrial disuse bone loss. Prolonged unloading and radiation exposure, defining characteristics of space travel, have both been associated with changes in inflammatory signaling via IL-6 class cytokines in bone. While there is also some evidence for perturbed IL-6 class signaling in spaceflight, there has been scant examination of the connections between free fall, radiation, and inflammatory stimuli in bone. Our lab and others have shown that the IL-6 class cytokine oncostatin M (OSM) is an important regulator of bone remodeling. We hypothesize that spaceflight alters osteoblast OSM signaling, …

Twenty-One Days Of Lunar Environment Alters Muscle Fiber Areas In Mouse Gastrocnemius, Edwin M. Savio, Kevin L. Shimkus, Jeff M. Hord, John Will Deaver, Michael P. Wiggs, Brandon R. Macias, Florence Lima, Ramon D. Boudreaux, Yasaman Shirazi-Fard, Elizabeth S. Greene, Les A. Braby, Harry A. Hogan, John M. Lawler, Susan A. Bloomfield, James D. Fluckey

International Journal of Exercise Science: Conference Proceedings

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Minimum Criteria For Dna Damage-Induced Phase Advances In Circadian Rhythms, Christian I. Hong, Judit Zámborszky, Attila Csikász-Nagy

Dartmouth Scholarship

Robust oscillatory behaviors are common features of circadian and cell cycle rhythms. These cyclic processes, however, behave distinctively in terms of their periods and phases in response to external influences such as light, temperature, nutrients, etc. Nevertheless, several links have been found between these two oscillators. Cell division cycles gated by the circadian clock have been observed since the late 1950s. On the other hand, ionizing radiation (IR) treatments cause cells to undergo a DNA damage response, which leads to phase shifts (mostly advances) in circadian rhythms. Circadian gating of the cell cycle can be attributed to the cell cycle …

Mites On Kangaroo Rats At The Nevada Test Site, Morris A. Goates

Brigham Young University Science Bulletin, Biological Series

A systematic study of parasitic mites on kangaroo rats of two species at the Nevada Test Site was conducted from August 1959 to December 1961. The intent was to determine the kinds, numbers, seasonal occurrences and ecological relationships of mites in nuclear disturbed and contiguous undisturbed areas. A total of 1,256 rats from nine plant communities was examined.

The 6,208 mites collected represented 16 species including four undescribed. Fourteen were found on both kinds of rats. Considerably more rats were infested with chiggers than with mesostigmatids. Each species of mite occurred alone on its host at least 20% of the …