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Articles 1 - 4 of 4
Full-Text Articles in Life Sciences
Decreased Activity Of Phosphofructokinase-1 In Flight Muscle Cells Of Hawk Moth Manduca Sexta With Age, Owen G. Alvine
Decreased Activity Of Phosphofructokinase-1 In Flight Muscle Cells Of Hawk Moth Manduca Sexta With Age, Owen G. Alvine
Honors Thesis
The phosphofructokinase-1 (PFK-1) enzyme is important for the catalyzation and regulation of glycolysis, especially in muscle. Investigating age-related changes in PFK-1 activity will provide insights into the metabolism shifts in muscle cells of our muscle aging model. The hawk moth, Manduca sexta, was chosen as the model organism because of its unique endothermic, synchronous flight muscles that are more analogous to vertebrates than invertebrate species. We hypothesized that PFK-1 activity will increase in muscle cells of aged moths due to dysregulation of the mitochondria. This was predicted to change the method of energy production, by hindering oxidative phosphorylation, making glycolysis …
The Potential Influence Of Abiotic Conditions On Mussel Species Abundance In San Francisco Bay, Alexandra G. Farrell, M. Christina Vasquez Dr.
The Potential Influence Of Abiotic Conditions On Mussel Species Abundance In San Francisco Bay, Alexandra G. Farrell, M. Christina Vasquez Dr.
Honors Thesis
Climate change has negatively altered seawater conditions, which may have severe implications for marine ecosystems. Mussels are susceptible to environmental changes since they are primary consumers and filter-feeding bivalves. Two species of particular interest to the West Coast of the U.S. are Mytilus galloprovincialis and M. trossulus. M. trossulus is native to the California Coast and was historically prevalent from Southern California to Washington. However, with increased shipping and rising seawater temperature, M. galloprovincialis, an invasive species from the Mediterranean, pushed the species range of M. trossulus poleward. M. trossulus is more tolerant of cold seawater with variable salinity while …
Mechanisms Of Synthetic Cannabinoids On Cardiovascular Health, Madeleine A. Nelson
Mechanisms Of Synthetic Cannabinoids On Cardiovascular Health, Madeleine A. Nelson
Honors Thesis
Cannabinoids encompass natural cannabis and synthetic cannabinoids. While the synthetic cannabinoids interact with the same endogenous system as cannabis, their effects are quite different and poorly understood. In addition to psychological effects that trigger their use, these substances are linked to cardiovascular morbidity. To assess the cardiovascular effect of synthetic cannabinoids, we first tested the hypothesis that intravenous administration of a synthetic cannabinoid would increase blood pressure in conscious rats. Second, we tested the hypothesis that the sympathetic nervous system is involved by injecting a ganglion blocker to see if the cardiovascular response from synthetic cannabinoids would be blocked. Third, …
Effect Of Hyposaline Stress On Metabolic Rate Of The Invasive Mussel Mytilus Galloprovincialis, Hayley C. Hart
Effect Of Hyposaline Stress On Metabolic Rate Of The Invasive Mussel Mytilus Galloprovincialis, Hayley C. Hart
Honors Thesis
Climate change is predicted to decrease ocean salinity as the polar ice caps melt and the occurrence of precipitation events increases. Decreased ocean salinity (hyposalinity) may negatively impact marine invertebrates, especially marine mussels, as they are osmoconformers and their internal osmolarity depends on the solute concentration of their environment. Hyposalinity stress may influence cell function and alter mussel physiology. To compensate for the change in the environment, mussels may expend more energy to restore internal osmolarity, which can be assessed by quantifying metabolic rate. Thus, the purpose of our research was to examine the physiological response of Mytilus galloprovincialis, …