Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 31 - 40 of 40

Full-Text Articles in Life Sciences

Clinical Management Of Intersex Abnormalities, Patricia Donahoe, David Powell, Mary Lee Sep 2014

Clinical Management Of Intersex Abnormalities, Patricia Donahoe, David Powell, Mary Lee

Mary M. Lee

No abstract provided.


Effect Of E. Coli Endotoxin On Mammalian Cell Growth And Recombinant Protein Production, J. Epstein, Mary Lee, C. Kelly, Patricia Donahoe Sep 2014

Effect Of E. Coli Endotoxin On Mammalian Cell Growth And Recombinant Protein Production, J. Epstein, Mary Lee, C. Kelly, Patricia Donahoe

Mary M. Lee

No abstract provided.


Physical Growth And Sexual Maturation Of Boys In Chapaevsk, Russia, Mary Lee, Oleg Sergeyev, Paige Williams, Susan Korrick, Vladimir Zeilert, Boris Revich, Russ Hauser Sep 2014

Physical Growth And Sexual Maturation Of Boys In Chapaevsk, Russia, Mary Lee, Oleg Sergeyev, Paige Williams, Susan Korrick, Vladimir Zeilert, Boris Revich, Russ Hauser

Mary M. Lee

We characterized physical growth and sexual maturation in 2,579 boys, ages 10 through 16.99 years, residing in Chapaevsk, Russia in order to establish region-specific reference data. Age-specific norms were established for height, weight, and BMI, and compared to US reference data by z-score analysis, while mean heights and weights by age were compared to published national Russian data. Compared to US boys, height was slightly lower (overall z-score -0.18) at all ages except the oldest (16-16.99 yr), while weight and BMI were moderately lower (overall z-score -0.52 and -0.61, respectively). Chapaevsk boys were significantly taller (1.15 cm) and thinner (-1.28 …


Mullerian Inhibiting Substance Messenger Ribonucleic Acid Expression In Granulosa And Sertoli Cells Coincides With Their Mitotic Activity, Seiichi Hirobe, Wei He, Mary Lee, Patricia Donahoe Sep 2014

Mullerian Inhibiting Substance Messenger Ribonucleic Acid Expression In Granulosa And Sertoli Cells Coincides With Their Mitotic Activity, Seiichi Hirobe, Wei He, Mary Lee, Patricia Donahoe

Mary M. Lee

In males, Mullerian inhibiting substance (MIS) mRNA was first detected on the medial aspect of the urogenital ridge early on the morning of day 13 of gestation before testicular differentiation was evident, and localized to the more obvious Sertoli cells later on embryonic day 13. MIS transcripts remained at maximal levels between 14.5 and 17.5 days gestation, while the Mullerian duct involutes, and remained high until birth. MIS gene expression decreased progressively after birth and, as germ cell meiosis increased, became barely detectable in the Sertoli cells of the seminiferous tubules. In female rats, MIS mRNA was first detected in …


Guidelines For The Use Of Growth Hormone In Children With Short Stature., Mary Lee Sep 2014

Guidelines For The Use Of Growth Hormone In Children With Short Stature., Mary Lee

Mary M. Lee

On the basis of the information currently available, the only conditions in which GH therapy appears to be safe and effective in increasing adult height are GH deficiency and, likely, Turner syndrome. Therapy with GH also increases the growth velocity of children with CRI and may increase adult height, but no long-term data are available. Encouraging short-term results have been reported in patients with a few other conditions, such as patients with glucocorticoid-induced growth failure, renal transplantation, and Prader-Willi syndrome, but the data are limited and no long-term studies have been reported; in many other conditions the data are either …


Correlation Of Cognitive Test Scores And Adequacy Of Treatment In Adolescents With Congenital Hypothyroidism., Mary Lee Sep 2014

Correlation Of Cognitive Test Scores And Adequacy Of Treatment In Adolescents With Congenital Hypothyroidism., Mary Lee

Mary M. Lee

PURPOSE: To measure the frequency of noncompliance and its possible effect on school achievement test and cognitive test scores in our older patients with congenital hypothyroidism. METHODS: Fifty patients born from 1976 through 1978 were studied at home when they were 14 years of age. Each patient was given a battery of psychometric and school achievement tests, and blood for hormonal assays was drawn without forewarning from 36 of the patients on the day of examination. Efforts were made to improve control after the second year. During the third summer the tests were repeated in 25 of the 29 patients …


The Orientation Of Strophomenid Brachiopods On Soft Substrates, Roy Plotnick, Benjamin Dattilo, Daniel Piquard, Jennifer Bauer, Joshua Corrie Jul 2014

The Orientation Of Strophomenid Brachiopods On Soft Substrates, Roy Plotnick, Benjamin Dattilo, Daniel Piquard, Jennifer Bauer, Joshua Corrie

Benjamin F. Dattilo

Strophomenid brachiopods have long been interpreted as ‘‘snowshoe’’ strategists, with their flattened concavoconvex valves providing resistance to foundering in very soft sediments. There has been a sharp difference of opinion in whether the shells were oriented with their convex or their concave surface in contact with the sediment. This study, along with independent evidence from sedimentology, ichnology, and morphology, indicates that the strophomenids lived with their shells concave down (convex up). Experiments indicate the force required to push shells into soft cohesive muds is much greater for the convex up than for the convex down orientation. Forces also increase with …


Effects Of Foot Position During Squatting On The Quadriceps Femoris: An Electromyographic Study, Nicholas Murray, Daniel Cipriani, Denise O'Rand, Rebecca Reed-Jones Apr 2014

Effects Of Foot Position During Squatting On The Quadriceps Femoris: An Electromyographic Study, Nicholas Murray, Daniel Cipriani, Denise O'Rand, Rebecca Reed-Jones

Daniel Cipriani

International Journal of Exercise Science 6(2) : 114-125, 2013. Weightlifters have commonly believed that changing joint position can alter specific muscle activation. The magnitude of force produced by a muscle is highly dependent upon the length of the muscle. The purpose of this study was to determine the effect of foot positioning on muscle activation of the superficial quadriceps as measured by surface electromyography (sEMG) during a functional squatting movement in healthy adults. Twenty physically active asymptomatic adults (7 females and 13 males) were included in the study while four different foot positions (Neutral, Internally Rotated, Externally Rotated, and Staggered) …


Knowledge And Attitudes Of University Female Athletes About The Female Athlete Triad, James D. Ramsay Mar 2014

Knowledge And Attitudes Of University Female Athletes About The Female Athlete Triad, James D. Ramsay

James D. Ramsay

Since the Female Athlete Triad was published in 1992, many efforts have been made to alert the athletic community about the relationship which is shared by disordered eating, amenorrhea and osteoporosis. The knowledge of athletes was investigated at three Midwestern universities regarding the female athlete triad. A total of 189 athletes from two Division III institutions and one Division I institution participated. Overall the subjects had normal height, weight, and body mass index. Most athletes knew they were at risk for osteoporosis at their age, however they did not understand the association it had with amenorrhea. At the Division I …


Effects Of Direct-Fed Microbial Supplementation On Broiler Performance, Intestinal Nutrient Transport And Integrity Under Experimental Conditions With Increased Microbial Challenge, G. R. Murugesan, N. K. Gabler, M. E. Persia Dec 2013

Effects Of Direct-Fed Microbial Supplementation On Broiler Performance, Intestinal Nutrient Transport And Integrity Under Experimental Conditions With Increased Microbial Challenge, G. R. Murugesan, N. K. Gabler, M. E. Persia

G. R. Murugesan

1. The effects of Aspergillus oryzae- and Bacillus subtilis- based direct-fed microbials (DFM) were investigated on the performance, ileal nutrient transport and intestinal integrity of broiler chickens, raised under experimental conditions, with increased intestinal microbial challenge. 2. The first study was a 3 × 2 factorial experiment, with 3 dietary treatments (control (CON), CON + DFM and CON + antibiotic growth promoter) with and without challenge. Chicks were fed experimental diets from 1 to 28 d, while the challenge was provided by vaccinating with 10 times the normal dose of commercial coccidial vaccine on d 9. In a second experiment, …