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Full-Text Articles in Life Sciences
Linking Environmental Toxicant Exposure To Diabetes Susceptibility, Jannifer Beth Tyrrell
Linking Environmental Toxicant Exposure To Diabetes Susceptibility, Jannifer Beth Tyrrell
Wayne State University Dissertations
An important and unresolved question in the environmental health field is whether exposure to common environmental toxicants, such as dioxin and heavy metals like Pb, increase the risk of developing diabetes, especially in combination with other common metabolic stressors such as obesity.
Previous studies suggested that dioxin exposure increased peripheral insulin resistance but did not appear to cause fasting hyperglycemia or elevated hepatic glucose output. In concordance with those findings we observed that dioxin treatment caused a strong suppression of the expression of the key hepatic gluconeogenic genes PEPCK and G6Pase. However, this suppression was not solely mediated by the …
The Effect Of Alpha-Cyclodextrin On Acute Blood Lipid And Glycemic Responses To A Fat Containg Meal, Evan Neil Fletcher
The Effect Of Alpha-Cyclodextrin On Acute Blood Lipid And Glycemic Responses To A Fat Containg Meal, Evan Neil Fletcher
Wayne State University Theses
Obesity and hyperlipidemia have become major concerns in the United States over the past 30 years. Alpha-Cyclodextrin (á-CD), a naturally occurring soluble dietary fiber, has been shown to reduce dietary fat absorption and improve blood lipid levels in an animal model (mouse and rat) and in human studies. In the current double blind study, 34 healthy male and female participants were recruited to test if á-CD had any acute effect on blood lipid and glycemic responses to a fat containing meal. The participants received the á-CD on one occasion and a placebo the other to determine if there was any …
Anti-Lipase Activity Of Quercus Infectoria G.Olivier Extract, Sirinan Thubthimthed., Sarunya Laovitthayanggoon, Parkpoom Siriarchavatana, Konlawit Chaithongsri, Chuleratana Banchonglikitkul
Anti-Lipase Activity Of Quercus Infectoria G.Olivier Extract, Sirinan Thubthimthed., Sarunya Laovitthayanggoon, Parkpoom Siriarchavatana, Konlawit Chaithongsri, Chuleratana Banchonglikitkul
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Exposure To Persistent Organic Pollutants And Metabolic Diseases, Zafar Zayirovich Aminov
Exposure To Persistent Organic Pollutants And Metabolic Diseases, Zafar Zayirovich Aminov
Legacy Theses & Dissertations (2009 - 2024)
Background: The metabolic syndrome (MetS) is a group of diseases that tend to occur together, including diabetes, hypertension, central obesity, cardiovascular disease and hyperlipidemia. Exposure to persistent organic pollutants (POPs) such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) have been associated with increased risk of development of several of the components of the MetS.