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Articles 91 - 109 of 109
Full-Text Articles in Life Sciences
Structural Features Of 1,3,4-Thiadiazole-Derived Ligands And Their Zn(Ii) And Cu(Ii) Complexes Which Demonstrate Synergistic Antibacterial Effects With Kanamycin, Dariusz Karcz, Arkadiusz Matwijczuk, Daniel Kaminski, Bernadette Creaven, Katarzyna Lecka-Szlachta, Karolina Starzak
Structural Features Of 1,3,4-Thiadiazole-Derived Ligands And Their Zn(Ii) And Cu(Ii) Complexes Which Demonstrate Synergistic Antibacterial Effects With Kanamycin, Dariusz Karcz, Arkadiusz Matwijczuk, Daniel Kaminski, Bernadette Creaven, Katarzyna Lecka-Szlachta, Karolina Starzak
Articles
Classical synthetic protocols were applied for the isolation of three novel 1,3,4-thiadiazole derivatives which were then complexed with the biologically important Cu(II) and Zn(II) ions. All free ligands and their corresponding complexes were characterized using a number of spectroscopic techniques including Ultraviolet-visible (UV–vis), Fluorescence, Infrared (FT-IR), tandem liquid chromatography-mass (LC-MS), X-ray diffraction (XRD), and Nuclear Magnetic Resonance (NMR) spectroscopy (1H, 13C, HSQC, HMBC). The results obtained are consistent with the formation of dihydrate complexes, in which the chelation of the metal ion occurs via one of the thiadiazole nitrogen atoms and the deprotonated hydroxyl group of the …
Calcium Carbonate, Kristina Fritz, Katherine Taylor, Mayur S. Parmar
Calcium Carbonate, Kristina Fritz, Katherine Taylor, Mayur S. Parmar
HPD Articles
No abstract provided.
Sodium Oxybate, Alvio Dominguez, Lucia Soca Gallego, Mayur S. Parmar
Sodium Oxybate, Alvio Dominguez, Lucia Soca Gallego, Mayur S. Parmar
HPD Articles
No abstract provided.
Lamivudine, Katherine Taylor, Kristina Fritz, Mayur S. Parmar
Lamivudine, Katherine Taylor, Kristina Fritz, Mayur S. Parmar
HPD Articles
No abstract provided.
Pralidoxime, Rishab Gupta, Mayur S. Parmar
Teriparatide, Hacen Vall, Mayur S. Parmar
Dornase Alfa, Rida Altaf, Mayur S. Parmar
Famciclovir, Jennifer R. Semaan, Mayur S. Parmar
Fluorescein, Amy-Grace Pothen, Mayur S. Parmar
Doxycycline Hyclate, Reema S. Patel, Mayur S. Parmar
Doxycycline Hyclate, Reema S. Patel, Mayur S. Parmar
HPD Articles
No abstract provided.
Fosinopril, Kaitlyn Alessi, Mayur S. Parmar
Indinavir, Eliyah B. Pollak, Mayur S. Parmar
Pramipexole, Raman Singh, Mayur S. Parmar
Tolterodine, Shreya Narain, Mayur S. Parmar
Measuring Functional Brain Recovery In Regenerating Planarians By Assessing The Behavioral Response To The Cholinergic Compound Cytisine, Oné R. Pagán, Debra L. Baker, Sean Deats, Mary O'Brien, Rochelle Dymond, Gabriella Demichele
Measuring Functional Brain Recovery In Regenerating Planarians By Assessing The Behavioral Response To The Cholinergic Compound Cytisine, Oné R. Pagán, Debra L. Baker, Sean Deats, Mary O'Brien, Rochelle Dymond, Gabriella Demichele
Biology Faculty Publications
Planarians are traditional model invertebrates in regeneration and developmental biology research that also display a variety of quantifiable behaviors useful to screen for pharmacologically active compounds. One such behavior is the expression of seizure-like movements (pSLMs) induced by a variety of substances. Previous work from our laboratory showed that cocaine, but not nicotine, induced pSLMs in intact but not decapitated planarians. Interestingly, as decapitated planarians regenerated their heads, they gradually recovered their sensitivity to cocaine. These results suggested a method to assess planarian brain regeneration and a possible way of identifying compounds that could enhance or hold back brain regeneration. …
Total Cellular Atp Production Changes With Primary Substrate In Mcf7 Breast Cancer Cells., Maggie Louie, Justin Ton, Maurice L. Brady, Diem T. Le, Jordon N. Mar, Chad A Lerner, Akos A Gerencser, Shona A. Mookerjee
Total Cellular Atp Production Changes With Primary Substrate In Mcf7 Breast Cancer Cells., Maggie Louie, Justin Ton, Maurice L. Brady, Diem T. Le, Jordon N. Mar, Chad A Lerner, Akos A Gerencser, Shona A. Mookerjee
Natural Sciences and Mathematics | Faculty Scholarship
Cancer growth is predicted to require substantial rates of substrate catabolism and ATP turnover to drive unrestricted biosynthesis and cell growth. While substrate limitation can dramatically alter cell behavior, the effects of substrate limitation on total cellular ATP production rate is poorly understood. Here, we show that MCF7 breast cancer cells, given different combinations of the common cell culture substrates glucose, glutamine, and pyruvate, display ATP production rates 1.6-fold higher than when cells are limited to each individual substrate. This increase occurred mainly through faster oxidative ATP production, with little to no increase in glycolytic ATP production. In comparison, non-transformed …
Distribution And Evolution Of Fukushima Dai-Ichi Derived 137cs, 90sr, And 129i In Surface Seawater Off The Coast Of Japan, Jennifer A. Kenyon, Ken O. Buesseler, Núria Casacuberta, Maxi Castrillejo, Shigeyoshi Otosaka, Pere Masqué, Jessica A. Drysdale, Steven M. Pike, Virginie Sanial
Distribution And Evolution Of Fukushima Dai-Ichi Derived 137cs, 90sr, And 129i In Surface Seawater Off The Coast Of Japan, Jennifer A. Kenyon, Ken O. Buesseler, Núria Casacuberta, Maxi Castrillejo, Shigeyoshi Otosaka, Pere Masqué, Jessica A. Drysdale, Steven M. Pike, Virginie Sanial
Research outputs 2014 to 2021
© 2020 American Chemical Society. The Fukushima Dai-ichi Nuclear Power Plants (FDNPPs) accident in 2011 led to an unprecedented release of radionuclides into the environment. Particularly important are 90Sr and 137Cs due to their known health detriments and long half-lives (T1/2 ≈ 30 y) relative to ecological systems. These radionuclides can be combined with the longer-lived 129I (T1/2 = 15.7 My) to trace hydrologic, atmospheric, oceanic, and geochemical processes. This study seeks to evaluate 137Cs, 90Sr, and 129I concentrations in seawater off the coast of Japan, reconcile the sources of contaminated waters, and assess the application of 137Cs/90Sr, 129I/137Cs, and …
Fine, Elaine - Covid-19 Journal, Elaine Fine
Fine, Elaine - Covid-19 Journal, Elaine Fine
Personal Journals
COVID Diary submitted by Charleston/Coles County, IL resident and musician, Elaine Fine
Host Abundance Correlates With Gulf War Illness Symptom Persistence Via Nlrp3-Mediated Neuroinflammation And Decreased Brain-Derived Neurotrophic Factor, Diana Kimono, Dipro Bose, Ratanesh K. Seth, Ayan Mondal, Punnag Saha, Patricia Janulewicz, Kimberly Sullivan, Stephen Lasley, Ronnie Horner, Nancy Klimas, Saurabh Chatterjee
Host Abundance Correlates With Gulf War Illness Symptom Persistence Via Nlrp3-Mediated Neuroinflammation And Decreased Brain-Derived Neurotrophic Factor, Diana Kimono, Dipro Bose, Ratanesh K. Seth, Ayan Mondal, Punnag Saha, Patricia Janulewicz, Kimberly Sullivan, Stephen Lasley, Ronnie Horner, Nancy Klimas, Saurabh Chatterjee
Faculty Publications
Neurological disorders are commonly reported among veterans who returned from the Gulf war. Veterans who suffer from Gulf War illness (GWI) complain of continued symptom persistence that includes neurological disorders, muscle weakness, headaches, and memory loss, that developed during or shortly after the war. Our recent research showed that chemical exposure associated microbial dysbiosis accompanied by a leaky gut connected the pathologies in the intestine, liver, and brain. However, the mechanisms that caused the symptoms to persist even 30 years after the war remained elusive to investigators. In this study, we used a rodent model of GWI to investigate the …