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Rat Hind Limb Nociceptive Withdrawal Response Depends On Initial Paw Position But Not Stimulus Location, Kimberly Seamon
Rat Hind Limb Nociceptive Withdrawal Response Depends On Initial Paw Position But Not Stimulus Location, Kimberly Seamon
Senior Honors Projects, 2010-2019
There have been numerous studies in non-human animals on the effect of stimulus location on the NWR and at least a few studies that address the role of initial posture. However, all of these studies were conducted in anesthetized, decerebrated, or spinalized mammals. Since descending modulation and long loop reflexes may influence the NWR, the anesthetized spinalized/decerebrated animal may not be an adequate model of normal animals. Therefore, the primary aim of this study was to determine the effect of the stimulus location and initial paw position on the direction and magnitude of the nociceptive withdrawal response to heat stimulus …
Multimodal Inputs And Modularity Of The Inferior Colliculus Prior To Audition., Joseph A. Balsamo
Multimodal Inputs And Modularity Of The Inferior Colliculus Prior To Audition., Joseph A. Balsamo
Senior Honors Projects, 2010-2019
A fully functional nervous system requires assimilation of sensory modalities to adequately interpret stimuli and determine appropriate motor responses. Two such regions responsible for multimodal integration are found in the auditory system, the cochlear nucleus (CN) and the inferior colliculus (IC). The lateral cortex of the IC (LCIC) in particular receives a diverse multimodal input array to discrete modular/extramodular zones. Staining for certain neurochemicals, including GAD, a marker for GABAergic neurons, reveal this compartmentalized LCIC organization. The present study utilizes fluorescent anterograde tracttracing techniques to determine the development of a somatosensory brainstem projection from the spinal trigeminal nucleus (Sp5), to …