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Articles 61 - 77 of 77
Full-Text Articles in Life Sciences
Familial Childhood Sleep Apnea, Robert M. Wittig, Frank J. Zorick, Timothy A. Roehrs, Jeanne M. Sicklesteel, Thomas Roth
Familial Childhood Sleep Apnea, Robert M. Wittig, Frank J. Zorick, Timothy A. Roehrs, Jeanne M. Sicklesteel, Thomas Roth
Henry Ford Hospital Medical Journal
We report four siblings who had polysomnographically documented sleep apnea. Two presented with the typical clinical picture of sleep apnea syndrome including daytime somnolence and snoring, had repetitive obstructive apneic episodes during sleep, and were effectively treated with upper airway surgery. The other two were asymptomatic and showed infrequent apneic episodes during sleep. This family illustrates the distinction between the sleep apnea syndrome and infrequent apneic episodes during sleep. The sleep apnea syndrome is associated with daytime symptomatology and requires treatment. The presence of apneic episodes during sleep in all four siblings has implications regarding the predisposing factors (eg, upper …
Sleep-Wake Complaints And Their Relation To Sleep Disturbance, De Ton, Frank J. Zorick, Timothy A. Roehrs, Robert M. Wittig, Jeanne M. Sicklesteel, Thomas Roth
Sleep-Wake Complaints And Their Relation To Sleep Disturbance, De Ton, Frank J. Zorick, Timothy A. Roehrs, Robert M. Wittig, Jeanne M. Sicklesteel, Thomas Roth
Henry Ford Hospital Medical Journal
This report is a comparison of patients presenting with 1) an insomnia complaint diagnosed as no objective findings. 2) insomnia diagnosed as being associated with a psychiatric disorder, and 3) daytime sleepiness diagnosed as no objective findings. The sleep of patients with insomnia diagnosed as no objective findings is comparable to that of patients with daytime sleepiness diagnosed as no objective findings and is significantly better than that of patients with insomnia associated with a psychiatric disorder. Significant differences were found in sleep induction, sleep maintenance, and overall sleep efficiency. No major differences were found among any of the groups …
A Mathematical Model Of Lung Static Pressure-Volume Relationships: Comparison Of Clinically Derived Parameters Of Elasticity, William Benish, Peggy Harper, Joseph Ward, John Popovich Jr.
A Mathematical Model Of Lung Static Pressure-Volume Relationships: Comparison Of Clinically Derived Parameters Of Elasticity, William Benish, Peggy Harper, Joseph Ward, John Popovich Jr.
Henry Ford Hospital Medical Journal
We constructed a simple model of lung distensibility in which the relationship between pressure (P) and volume (V) is of the exponential form obtained empirically: V = a+ becP , where a, b, and c are constants, and e is the base of the natural logarithm. The model lung is idealized as a frictionless diaphragm moving in a cylinder. Diaphragm movement is impeded by a variable force (F). By assuming that the rate of change of F is proportional to the inverse of the distance of the diaphragm from a maximal distance, the pressure-volume relationship assumes the above exponential form. …
Clinical Significance Of Sleep Desaturation In Hypoxemic Chronic Obstructive Pulmonary Disease: Studies In 130 Patients, William A. Conway, Meir Kryger, Richard M. Timms, George W. Williams
Clinical Significance Of Sleep Desaturation In Hypoxemic Chronic Obstructive Pulmonary Disease: Studies In 130 Patients, William A. Conway, Meir Kryger, Richard M. Timms, George W. Williams
Henry Ford Hospital Medical Journal
We studied 130 patients with hypoxemic chronic obstructive lung disease to determine if nocturnal desaturation aggravates hypoxia-induced complications. All had tests of neuropsychological and physiological function known to be affected by chronic hypoxia. Of the 130 patients, 25 had complete polysomnography and 105 had their sleep judged visually and arterial oxygen saturation recorded continuously. Severe and mild desaturation groups were defined relative to the mean for both mean and maximal sleep desaturation, and the severity of waking complications were compared. No significant differences were noted between patients with mild and severe mean desaturation or maximal desaturation for hematocrit, neuropsychological tests, …
Anticoagulant And Antithrombotic Therapy In Deep Venous Thrombosis And Pulmonary Embolism, Paul D. Stein
Anticoagulant And Antithrombotic Therapy In Deep Venous Thrombosis And Pulmonary Embolism, Paul D. Stein
Henry Ford Hospital Medical Journal
No abstract provided.
Disseminated Strongyloides Stercoralis And Aspergillus Fumigatus Presenting As Diffuse Interstitial Pneumonitis In A Steroid-Dependent Chronic Obstructive Pulmonary Disease Patient, Larry Tankanow, Michael S. Eichenhorn
Disseminated Strongyloides Stercoralis And Aspergillus Fumigatus Presenting As Diffuse Interstitial Pneumonitis In A Steroid-Dependent Chronic Obstructive Pulmonary Disease Patient, Larry Tankanow, Michael S. Eichenhorn
Henry Ford Hospital Medical Journal
We describe a patient with long-standing steroid-dependent chronic obstructive pulmonary disease who was admitted with new diffuse interstitial pulmonary infiltrates. Strongyloides stercoralis was present in the sputum and stool and responded to treatment. However, complicating disseminating Aspergillus fumigatus infection eventuated in the patient's death. Strongyloides stercoralis infection should be considered in patients with relevant exposure history, and complicating fungal and gram-negative bacterial infections which such patients may develop should be suspected.
Clinical Manifestations Of Acute Pulmonary Embolism: Henry Ford Hospital Experience, A Five-Year Review, Kenneth V. Leeper Jr., John Popovich Jr., Deborah Adams, Paul D. Stein
Clinical Manifestations Of Acute Pulmonary Embolism: Henry Ford Hospital Experience, A Five-Year Review, Kenneth V. Leeper Jr., John Popovich Jr., Deborah Adams, Paul D. Stein
Henry Ford Hospital Medical Journal
Clinical findings of 112 patients with angiographically proven pulmonary embolism over a five-year period were analyzed. Recent immobilization, chronic heart disease, deep venous thrombosis, malignancy, and recent surgery were the most frequent predisposing factors. Only 5% had no identifiable risk factors. Presenting syndromes were circulatory collapse (25%), pulmonary infarction (59%), and uncomplicated pulmonary embolism (18%). Dyspnea and pleuritic chest pain were the predominant symptoms. The combination of dyspnea, pleuritic chest pain, and hemoptysis occurred in 23% of the patients. The most frequent signs were tachypnea, tachycardia, and rales. Most of the patients demonstrated arterial oxygen tension (PaO2) between 50 and …
Cancer Mortality Among Residents Of Huron, Sanilac, And Tbscola Counties As Compared To Other Michigan Residents, 1971-1985, Jennifer A. Booms, William Benish
Cancer Mortality Among Residents Of Huron, Sanilac, And Tbscola Counties As Compared To Other Michigan Residents, 1971-1985, Jennifer A. Booms, William Benish
Henry Ford Hospital Medical Journal
Age-adjusted cancer mortality rates in the "Thumb" area of Michigan (Huron, Sanilac, and Tuscola counties) were compared with those for the rest of the state from 1971 to 1985. Comparisons were made after partitioning the mortality data on the basis of the patient's sex, year of death (1971 to 1975, 1976 to 1980, or 1981 to 1985), and site of primary tumor. International Classification of Diseases categories were combined to define 29 cancer site groups. The analysis was limited to the white population. The major observation was a consistently lower mortality rate of lung cancer in the Thumb area than …
Enteric-Coated Fenoprofen In Large-Joint Osteoarthritis, Gilbert B. Bluhm, Harris H. Macilwain, Walter W. Offen
Enteric-Coated Fenoprofen In Large-Joint Osteoarthritis, Gilbert B. Bluhm, Harris H. Macilwain, Walter W. Offen
Henry Ford Hospital Medical Journal
Enteric-coated fenoprofen was compared with standard fenoprofen (Nalfon, Dista, Indianapolis, IN) in a randomized, double-blind, parallel, three-month trial of 113 outpatients (mean age, 64 years) with large-joint osteoarthritis. A previous study showed that enteric coating of fenoprofen reduces gastrointestinal microbleeding and may offer a safety advantage. Both treatments provided statistically significant improvement in pain measures (tenderness on pressure, pain at rest, pain with weight-bearing activity, and pain on passive motion). Adverse experiences were similar with both treatments and of an expected type, severity, and incidence for nonsteroidal anti-inflammatory drugs. Enteric-coated fenoprofen was found to be as effective and safe as …
Malignant Lymphoma Presenting In Gluteal Muscles: Case Report And Brief Review Of The Literature, Roberta Sonnino, Angelos A. Kambouris
Malignant Lymphoma Presenting In Gluteal Muscles: Case Report And Brief Review Of The Literature, Roberta Sonnino, Angelos A. Kambouris
Henry Ford Hospital Medical Journal
No abstract provided.
Potency Of Current Levothyroxine Preparations Evaluated By High-Performance Liquid Chromatography, Sheldon S. Stoffer, Walter E. Szpunar
Potency Of Current Levothyroxine Preparations Evaluated By High-Performance Liquid Chromatography, Sheldon S. Stoffer, Walter E. Szpunar
Henry Ford Hospital Medical Journal
Ten different levothyroxine products manufactured by six companies were analyzed by high-performance liquid chromatography. Although nine products met the United States Pharmacopeia requirements, one product was found to have only 47% of expected potency. Until these products become more uniform, we would not recommend interchangeability of levothyroxine preparations.
Jack S. Guyton, Md, Cornelius E. Mccole
Jack S. Guyton, Md, Cornelius E. Mccole
Henry Ford Hospital Medical Journal
No abstract provided.
Editorial: Responsibilities Of Authorship: Justification Of The Multiauthored Scientific Paper, Sarah Whitehouse, Raymond C. Mellinger
Editorial: Responsibilities Of Authorship: Justification Of The Multiauthored Scientific Paper, Sarah Whitehouse, Raymond C. Mellinger
Henry Ford Hospital Medical Journal
No abstract provided.
A Prospective Randomized Comparison Of A Single Antibiotic (Moxalactam) Versus Combination Therapy (Gentamicin And Clindamycin) In Penetrating Abdominal Trauma, Theodore Fifer, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen, Larry D. Crots, Brack A. Bivins
A Prospective Randomized Comparison Of A Single Antibiotic (Moxalactam) Versus Combination Therapy (Gentamicin And Clindamycin) In Penetrating Abdominal Trauma, Theodore Fifer, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen, Larry D. Crots, Brack A. Bivins
Henry Ford Hospital Medical Journal
From July 1 to December 31, 1983, 50 consecutive patients undergoing abdominal exploration for penetrating abdominal trauma from stab and gunshot wounds were prospectively randomized to receive postinjury, preoperative antibiotic coverage with moxalactam (2 g intravenously every 12 hours) or a combination of gentamicin (3 to 5 mg/kg/day in three equal doses administered every eight hours) and clindamycin (600 mg intravenously every six hours). No intraabdominal abscesses or wound infections developed, and no direct evidence of toxicity of the antibiotic regimens developed in either group. In the study group, moxalactam therapy was an effective alternative to the combination antibiotic regimen. …
Oral Contraceptives And Fat Patterning In Young Adult Women, Ruth E. Litchfield, Katharine K. Grunewald
Oral Contraceptives And Fat Patterning In Young Adult Women, Ruth E. Litchfield, Katharine K. Grunewald
Ruth E. Litchfield
. Ninety white nulliparous young women (18-26 years of age) participated in a double-blind study designed to compare fat patterning and other physical measurements in oral contraceptive (OCA) users and non- users. Oral contraceptive users (N = 30) and non-users (N = 60) were matched on a 1:2 basis for height and weight. The OCA users and non- users had similar circumference and skinfold measurements, except that OCA users had larger axilla skinfold measurements. Progestational activity of the oral contraceptives was not associated with any measurements taken. However, estrogenic activity was positively correlated with measured body weight, body mass index, …
Sensitivity To Ingested Sulfites, Steve L. Taylor, Julie A. Nordlee
Sensitivity To Ingested Sulfites, Steve L. Taylor, Julie A. Nordlee
Department of Food Science and Technology: Faculty Publications
Sulfiting agents, including sodium and potassium bisulfite, sodium and potassium metabisulfite, sodium sulfite, and sulfur dioxide, have enjoyed widespread use as food and drug ingredients. The oral ingestion of these sulfiting agents is now known to trigger asthma in a small subset of the asthmatic population. The best evidence suggests that perhaps 150,000 to 200,000 individuals in the United States may be sulfite sensitive. Although the mechanism of sulfite-induced asthma remains unknown, several possibilities have been considered, including inhalation of sulfur dioxide (SO2) while swallowing, an IgE-mediated reaction, and a deficiency of sulfite oxidase leading to impaired sulfite …