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Full-Text Articles in Life Sciences

Combined Anthocyanins And Bromelain Supplement Improves Endothelial Function And Skeletal Muscle Oxygenation Status In Adults: A Double-Blind Placebo-Controlled Randomised Crossover Clinical Trial, Elizabeth J. Pekas, Jaehyun Shin, Ronald Headid Iii, Won-Mok Son, Gwenael Layec, Santosh K. Yadav, Steven D. Scott, Song-Young Park Jul 2020

Combined Anthocyanins And Bromelain Supplement Improves Endothelial Function And Skeletal Muscle Oxygenation Status In Adults: A Double-Blind Placebo-Controlled Randomised Crossover Clinical Trial, Elizabeth J. Pekas, Jaehyun Shin, Ronald Headid Iii, Won-Mok Son, Gwenael Layec, Santosh K. Yadav, Steven D. Scott, Song-Young Park

Health and Kinesiology Faculty Publications

Anthocyanins and bromelain have gained significant attention due to their antioxidative and anti-inflammatory properties. Both have been shown to improve endothelial function, blood pressure (BP) and oxygen utility capacity in humans; however, the combination of these two and the impacts on endothelial function, BP, total antioxidant capacity (TAC) and oxygen utility capacity have not been previously investigated. The purpose of this study was to investigate the impacts of a combined anthocyanins and bromelain supplement (BE) on endothelial function, BP, TAC, oxygen utility capacity and fatigability in healthy adults. Healthy adults (n 18, age 24 (SD 4) years) received BE or …


Increased Sod2 In The Diaphragm Contributes To Exercise-Induced Protection Against Ventilator-Induced Diaphragm Dysfunction, Stephanie E. Hall Jan 2019

Increased Sod2 In The Diaphragm Contributes To Exercise-Induced Protection Against Ventilator-Induced Diaphragm Dysfunction, Stephanie E. Hall

Kinesiology Faculty Publications and Presentations

Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in rapid diaphragmatic atrophy and contractile dysfunction, collectively termed ventilator-induced diaphragm dysfunction (VIDD). Recent evidence reveals that endurance exercise training, performed prior to MV, protects the diaphragm against VIDD. While the mechanism(s) responsible for this exercise-induced protection against VIDD remain unknown, increased diaphragm antioxidant expression may be required. To investigate the role that increased antioxidants play in this protection, we tested the hypothesis that elevated levels of the mitochondrial antioxidant enzyme superoxide dismutase 2 (SOD2) is required to achieve exercise-induced protection against VIDD. Cause …


Increased Sod2 In The Diaphragm Contributes To Exercise-Induced Protection Against Ventilator-Induced Diaphragm Dysfunction, Aaron B. Morton, Ashley J. Smuder, Michael P. Wiggs, Stephanie E. Hall, Bumsoo Ahn, J. Matthew Hinkley, Noriko Ichinoseki-Sekine, Andres Mor Huertas, Mustafa Ozdemir, Toshinori Yoshihara, Nicholas R. Wawrzyniak, Scott K. Powers Oct 2018

Increased Sod2 In The Diaphragm Contributes To Exercise-Induced Protection Against Ventilator-Induced Diaphragm Dysfunction, Aaron B. Morton, Ashley J. Smuder, Michael P. Wiggs, Stephanie E. Hall, Bumsoo Ahn, J. Matthew Hinkley, Noriko Ichinoseki-Sekine, Andres Mor Huertas, Mustafa Ozdemir, Toshinori Yoshihara, Nicholas R. Wawrzyniak, Scott K. Powers

Health and Kinesiology Faculty Publications and Presentations

Mechanical ventilation (MV) is a life-saving intervention for many critically ill patients. Unfortunately, prolonged MV results in rapid diaphragmatic atrophy and contractile dysfunction, collectively termed ventilator-induced diaphragm dysfunction (VIDD). Recent evidence reveals that endurance exercise training, performed prior to MV, protects the diaphragm against VIDD. While the mechanism(s) responsible for this exercise-induced protection against VIDD remain unknown, increased diaphragm antioxidant expression may be required. To investigate the role that increased antioxidants play in this protection, we tested the hypothesis that elevated levels of the mitochondrial antioxidant enzyme superoxide dismutase 2 (SOD2) is required to achieve exercise-induced protection against VIDD. Cause …