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Full-Text Articles in Life Sciences
Growth Differentiation Factor 5 Is A Paracrine Regulator Of Sarcopenic Obesity, Landen W. Saling
Growth Differentiation Factor 5 Is A Paracrine Regulator Of Sarcopenic Obesity, Landen W. Saling
Graduate Theses and Dissertations
Sarcopenic obesity attributes to skeletal muscle loss more than sarcopenia and obesity alone. Individuals with SO suffer from the comorbidity of excess body fat and concurrent muscle mass loss due to aging. Growth differentiation factors (Gdfs) have never been recognized as playing a role in skeletal muscle maintenance in those with SO. Specifically, Gdf5, has been recognized as playing a part in Bone Morphogenic Protein signaling to activate protein synthesis and deactivate protein degradation via SMAD 1/5/8 and SMAD 4 complex. Using RNA sequencing, Gdf5 was identified as being significantly upregulated in SO mice. Purpose: To determine the cellular role …
Association Of Dietary Behaviors, Macro-Nutrients And Energy Intake With Body Fat Percentage, Lean Mass, And Bone Mineral Density., Makayla Goggins
Association Of Dietary Behaviors, Macro-Nutrients And Energy Intake With Body Fat Percentage, Lean Mass, And Bone Mineral Density., Makayla Goggins
Health, Human Performance and Recreation Undergraduate Honors Theses
Background: Due to the obesity epidemic, many studies have compared nutrient intake to human body composition. However, previous studies have not used gold standard measures of body composition in a college population. Purpose: The purpose of this study is to examine how dietary behaviors, overall energy intake, and macronutrient intake are associated with the body composition factors measured in a dual-energy x-ray absorptiometry (DXA) scan. We hypothesize higher body fat percentage will be associated with higher fat and carbohydrate intake, but not total energy intake. Methodology: This was a cross-sectional study done as part of Exercise is …
Autophagy Regulation After Diet And Exercise In Non-Alcoholic Fatty Liver Disease, Megan Elizabeth Rosa
Autophagy Regulation After Diet And Exercise In Non-Alcoholic Fatty Liver Disease, Megan Elizabeth Rosa
Graduate Theses and Dissertations
Along with the rise in obesity, rates of non-alcoholic fatty liver disease (NAFLD) have also increased. NAFLD may begin with fat accumulation in the liver, but can progress to non-alcoholic steatohepatitis (NASH), fibrosis, and eventual cirrhosis. With no pharmacological treatment for NASH, lifestyle interventions appear vital to maintaining liver health. Previous work has shown aberrant mitochondrial content/quality and autophagy in models of NAFLD. Exercise is known to improve mitochondrial health and possibly autophagy, thus autophagy may be a key regulatory factor for treatment of obesity induced-NAFLD. PURPOSE: The purpose of the study was to examine how weight loss from diet …
Effect Of Body Size And Exercise On Mood State, Alexandra Lachance
Effect Of Body Size And Exercise On Mood State, Alexandra Lachance
Graduate Theses and Dissertations
Exercising in the presence of nature (i.e., "green exercise"), has been shown to heighten the physiological and mental benefits of traditional exercise on non-obese individuals. The effects of green exercise on obese individuals are unknown. It is hypothesized that green exercise is more beneficial for obese (greater positive improvements in mental health scores), compared to non-obese individuals. For example, the benefits of green exercise could help lower feelings of depression, improve mood and self-esteem to increase the propensity of obese individuals to meet exercise recommendations. Accordingly, this study investigated the physiological and psychological effects of green exercise on 12 obese …
Effects Of Obesity On Thermoregulation And Cardiovascular Function During Exercise In Females, Jon David Adams
Effects Of Obesity On Thermoregulation And Cardiovascular Function During Exercise In Females, Jon David Adams
Graduate Theses and Dissertations
Previous research has shown that obese individuals are at greater risk for heat illnesses because of impaired thermoregulation. However, laboratory studies investigating cardiovascular and thermoregulatory function in obese individuals are difficult to interpret because of low sample sizes and methodological concerns. The purpose of this study was to determine if there are differences in thermoregulatory and cardiovascular function between obese and non-obese females. Twenty-four females, 13 obese (43.3 ± 4 .3 % fat, 77.2 ± 13.7 kg) and 11 non-obese (27.8 ± 6.0 % fat, 55.7±6.7 kg), cycled for 60 min in a warm environment (~40°C, 30% humidity) at a …