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Epidemiology

2017

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Full-Text Articles in Life Sciences

Metabolic Dysregulation And Cancer Mortality In A National Cohort Of Blacks And Whites, Tomi Akinyemiju, Justin Xavier Moore, Suzanne Judd, Susan Lakoski, Michael Goodman, Monika M. Safford, Maria Pisu Dec 2017

Metabolic Dysregulation And Cancer Mortality In A National Cohort Of Blacks And Whites, Tomi Akinyemiju, Justin Xavier Moore, Suzanne Judd, Susan Lakoski, Michael Goodman, Monika M. Safford, Maria Pisu

Epidemiology and Environmental Health Faculty Publications

Background: We examined the association between metabolic dysregulation and cancer mortality in a prospective cohort of Black and White adults.

Methods: A total of 25,038 Black and White adults were included in the analysis. Metabolic dysregulation was defined in two ways: 1) using the joint harmonized criteria for metabolic syndrome (MetS) and 2) based on factor analysis of 15 variables characterizing metabolic dysregulation. We estimated hazards ratios (HRs) and 95% confidence intervals (CIs) for the association of MetS and metabolic dysregulation with cancer mortality during follow-up using Cox proportional hazards models.

Results: About 46% of Black and 39% of White …


Quality Of Life: Socio-Demographic And Genetic Determinants As Well As Links With Cancer Outcomes, Jeanne Pierzynski Dec 2017

Quality Of Life: Socio-Demographic And Genetic Determinants As Well As Links With Cancer Outcomes, Jeanne Pierzynski

Dissertations & Theses (Open Access)

Quality of life (QOL) is an independent prognostic factor for cancer. Lung cancer is the leading cause of cancer death. Breast cancer is the most diagnosed. Bladder cancer is the most expensive cancer to treat because of its high recurrence rate. We set to perform comprehensive analyses of predictors of QOL in these cancer sites with the future goal of improving QOL and outcomes.

In 6,456 newly diagnosed lung cancer patients, we investigated the relationship between baseline patient characteristics and QOL to identify determinants of QOL. A QOL questionnaire (SF-12v1) measured patients’ physical component summary (PCS) and mental component summary …


The Change In Mental Health Status Of Indonesian Health Care Migrant Worker In Japan, Susiana Nugraha, Yuko Hirano, Honda Sumihisha Nov 2017

The Change In Mental Health Status Of Indonesian Health Care Migrant Worker In Japan, Susiana Nugraha, Yuko Hirano, Honda Sumihisha

Kesmas

Under the Japan – Indonesia Economic Partnership Agreement, more than 1,000 of Indonesian health care workers have migrated to Japan. Social adjustment during the process of migration is linked to mental health changes. This study aimed to figure out the strongest predictor that influences the change in mental health status as a result of migration. Baseline data were collected in Jakarta in 2013 during pre-departure orientation. Follow-up study was conducted one year after the study participants migrated to Japan in 2014. Using longitudinal design, this study employed 92 participants consisting of nurse and certified care worker candidates. The multiple linear …


Husband’S Education Level And Alcohol Drinking Habit As Risk Factors Of Hiv Infection Among Housewives In Pati District, Nurul Aeni, Annemarie Westendorp Nov 2017

Husband’S Education Level And Alcohol Drinking Habit As Risk Factors Of Hiv Infection Among Housewives In Pati District, Nurul Aeni, Annemarie Westendorp

Kesmas

Cases of Human Immunodeficiency Virus (HIV) infection in Pati District increase, particularly among housewives. The aim of this study was to analyse the risk factors of HIV infection among housewives in Pati District using case-control study design. The respondents were 90 housewives divided into case and control group. The case group consisted of 30 housewives living with HIV, while the control group comprised 60 housewives living in the similar area of the counterparts. The data collection was focused on demographic, sexual behaviour, and sociocultural variables possessed by housewives and their husbands. The study resulted that the risk factors of HIV …


Effect Of Health Education On Community Participation To Eradicate Aedes Aegypti-Breeding Sites In Buahbatu And Cinambo Districts, Bandung, Zahratul Elsa, Uun Sumardi, Lia Faridah Nov 2017

Effect Of Health Education On Community Participation To Eradicate Aedes Aegypti-Breeding Sites In Buahbatu And Cinambo Districts, Bandung, Zahratul Elsa, Uun Sumardi, Lia Faridah

Kesmas

Dengue hemorrhagic fever (DHF) is still a major public health problem in many regions in Indonesia including Bandung City. Community participation in implementing Eradication of Mosquito-Breeding Sites is still needed as it is considered the most effective method in controlling the dengue fever. This study aimed to determine the influence of health education towards community participation to eradicate mosquito-breeding sites, which was measured by knowledge level and larva index conducted in Bandung, specifically in two different locations with the highest and the lowest incidence rates of DHF. This study used quasi-experimental method. Samples were 100 people living in Cijawura and …


Maternal Energy Intake At The Sixth Month As Dominant Factor Of Exclusive Breastfeeding Success, Devi Suryanti Sihite, Sandra Fikawati, Ahmad Syafiq Nov 2017

Maternal Energy Intake At The Sixth Month As Dominant Factor Of Exclusive Breastfeeding Success, Devi Suryanti Sihite, Sandra Fikawati, Ahmad Syafiq

Kesmas

Breastfeeding mothers needed adequate energy intake to provide 6-month exclusive breastfeeding that is necessary for infant growth and development. This study aimed to investigate real intake at the first and sixth month of breastfeeding and determine the dominant factor affecting 6-month exclusive breastfeeding provision. The design of this study was cross-sectional conducted in March-April 2015 among 109 mothers with 6-12- month-old infant living and registered at integrated health care in Kalangan Primary Health Care area. Data were collected through interview using questionnaires. Breastfeeding mothers’ intake was asked using Semi-Quantitative Food Frequency Questionnaire. The study found that 6-month exclusive breastfeeding proportion …


Increasing Use Of Research Findings In Improving Evidence-Based Health Policy At The National Level, Meiwita Budiharsana Nov 2017

Increasing Use Of Research Findings In Improving Evidence-Based Health Policy At The National Level, Meiwita Budiharsana

Kesmas

In February 2016, the Minister of Health decided to increase the use of research findings in improving the quality of the national health policy and planning. The Ministry of Health has instructed the National Institute of Health Research and Development or NIHRD to play a stronger role of monitoring and evaluating all health programs, because “their opinion and research findings should be the basis for changes in national health policies and planning”. Compared to the past, the Ministry of Health has increased the research budget for evidence-based research tremendously. However, there is a gap between the information needs of program …


Spatial Analysis Of Determinants Of Filariasis-Endemic Areas In West Sumatra, Masrizal Masrizal, Fivi Melva Diana, Rosfita Rasyid Nov 2017

Spatial Analysis Of Determinants Of Filariasis-Endemic Areas In West Sumatra, Masrizal Masrizal, Fivi Melva Diana, Rosfita Rasyid

Kesmas

West Pasaman District and Agam District are filariasis-endemic areas in West Sumatra with prevalence of 12.40 per 100,000 cases and 11.27 per 100,000 cases respectively. This study aimed to determine risk factors associated with the prevalence of filariasis and mapping the vulnerability of the area in West Sumatra. A case control study design was conducted in the West Pasaman District and Agam District. The study used a sample of 74 cases and 74 controls taken by simple random sampling for the case and purposive random sampling for control. Data analysis used univariate, bivariate, multivariate and spatial. The results in Agam …


Equity Level Of Health Insurance Ownership In Indonesia, Risky Kusuma Hartono Nov 2017

Equity Level Of Health Insurance Ownership In Indonesia, Risky Kusuma Hartono

Kesmas

Social health insurance from government program are expected to be able to reduce inequalities access to health services in the middle of rising of health care cost, while private health insurance is still limited for up and middle class population. This study aimed to analyze the equity level of health insurance ownership including social and private health insurance in Indonesia. This study examined the condition of Indonesia in the middle of entering National Health Insurance (NHI) era. This study used data of Indonesian Socio-Economic Survey 2012. Data were analyzed by using econometric approach through multinomial logit analysis. The results showed …


Implementation Of Cigarette Excise Policy Against Cigarette Consumption Reduction Among Adolescent In Kuningan, Indonesia, Jani Ramjani, Fitri Kurnia Rahim, Icca Stella Amalia, Wahyu Manggala Putra Nov 2017

Implementation Of Cigarette Excise Policy Against Cigarette Consumption Reduction Among Adolescent In Kuningan, Indonesia, Jani Ramjani, Fitri Kurnia Rahim, Icca Stella Amalia, Wahyu Manggala Putra

Kesmas

Indonesia has the highest prevalence of smoking (50.68%) compared to other ASEAN countries. On January 1st, 2017, the Indonesian government raised cigarette excise taxes. The purpose of this study was to analysis the impact of cigarette excise increase on cigarette consumption among adolescents aged 17 to 25 years. The study design used cross-sectional survey. A total of 153 adolescents were recruited in this study through simple random sampling technique. Questionnaires and observation papers were used in this study. A face-to-face interview was conducted to fulfill the data collection through home visit for each respondent. The data were obtained during May …


Advancing Stroke Genomic Research In The Age Of Trans-Omics Big Data Science: Emerging Priorities And Opportunities, Mayowa Owolabi, Emmanuel Peprah, Huichun Xu, Rufus Akinyemi, Hemant K. Tiwari, Marguerite R. Irvin, Kolawole Wasiu Wahab, Donna K. Arnett, Bruce Ovbiagele Nov 2017

Advancing Stroke Genomic Research In The Age Of Trans-Omics Big Data Science: Emerging Priorities And Opportunities, Mayowa Owolabi, Emmanuel Peprah, Huichun Xu, Rufus Akinyemi, Hemant K. Tiwari, Marguerite R. Irvin, Kolawole Wasiu Wahab, Donna K. Arnett, Bruce Ovbiagele

Epidemiology and Environmental Health Faculty Publications

Background—We systematically reviewed the genetic variants associated with stroke in genome-wide association studies (GWAS) and examined the emerging priorities and opportunities for rapidly advancing stroke research in the era of Trans-Omics science.

Methods—Using the PRISMA guideline, we searched PubMed and NHGRI- EBI GWAS catalog for stroke studies from 2007 till May 2017.

Results—We included 31 studies. The major challenge is that the few validated variants could not account for the full genetic risk of stroke and have not been translated for clinical use. None of the studies included continental Africans. Genomic study of stroke among Africans presents …


Organic Solvent Exposure And Depressive Symptoms Among Licensed Pesticide Applicators In The Agricultural Health Study, Miriam Siegel, Sarah E. Starks, Wayne T. Sanderson, Freya Kamel, Jane A. Hoppin, Fred Gerr Nov 2017

Organic Solvent Exposure And Depressive Symptoms Among Licensed Pesticide Applicators In The Agricultural Health Study, Miriam Siegel, Sarah E. Starks, Wayne T. Sanderson, Freya Kamel, Jane A. Hoppin, Fred Gerr

Epidemiology and Environmental Health Faculty Publications

Purpose

Although organic solvents are often used in agricultural operations, neurotoxic effects of solvent exposure have not been extensively studied among farmers. The current analysis examined associations between questionnaire-based metrics of organic solvent exposure and depressive symptoms among farmers.

Methods

Results from 692 male Agricultural Health Study participants were analyzed. Solvent type and exposure duration were assessed by questionnaire. An “ever-use” variable and years of use categories were constructed for exposure to gasoline, paint/lacquer thinner, petroleum distillates, and any solvent. Depressive symptoms were ascertained with the Center for Epidemiologic Studies Depression Scale (CES-D); scores were analyzed separately as continuous (0–60) …


Id3, Estrogenic Chemicals, And The Pathogenesis Of Tumor-Like Proliferative Vascular Lesions, Vincent E. Avecilla Oct 2017

Id3, Estrogenic Chemicals, And The Pathogenesis Of Tumor-Like Proliferative Vascular Lesions, Vincent E. Avecilla

FIU Electronic Theses and Dissertations

Tumor-like proliferative vascular lesions manifest in several diseases such as peripheral arterial disease (PAD) and atherosclerosis (AS) after arterial injury. The cause of the vascular cell dysfunction in PAD patients is not known. Our recent novel discovery shows that inhibitor of differentiation 3 (ID3) is highly expressed in intimal lesions of clinical vascular disease samples. The central hypothesis of our study is: estrogenic chemical induced dysregulation of ID3 target genes is involved in the development of vascular disease. NHANES data analysis demonstrated higher geometric levels of all 6 PCB congeners in both PAD diagnosed participants and participants at risk of …


A Stochastic Epidemiological Model Of The Response Of American Chestnut Populations To Fungal Blight, Kelsey Lieberman, Rebecca Rouleau, Anita Davelos Baines, Martin Allen Oct 2017

A Stochastic Epidemiological Model Of The Response Of American Chestnut Populations To Fungal Blight, Kelsey Lieberman, Rebecca Rouleau, Anita Davelos Baines, Martin Allen

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Gender Differences In Virologic Response After Antiretroviral Therapy In Treatment-Naïve Hiv-Infected Individuals: Results From The 550 Clinic Hiv Cohort Study., Andrea Reyes-Vega, Alejandra Loban, Kavitha Srinivasan, Stephen P. Furmanek, Conner English, Mary Bishop, Cathy Spencer, Daniel Truelove, Julio A. Ramirez, Anupama Raghuram, Paula Peyrani Oct 2017

Gender Differences In Virologic Response After Antiretroviral Therapy In Treatment-Naïve Hiv-Infected Individuals: Results From The 550 Clinic Hiv Cohort Study., Andrea Reyes-Vega, Alejandra Loban, Kavitha Srinivasan, Stephen P. Furmanek, Conner English, Mary Bishop, Cathy Spencer, Daniel Truelove, Julio A. Ramirez, Anupama Raghuram, Paula Peyrani

Faculty Scholarship

Background

Controversy still exists regarding gender differences in virologic response between treatment-na•ve HIV-infected individuals. The objective of this study was to evaluate gender difference in virologic and immunologic response to antiretroviral therapy in treatment-na•ve HIV-infected individuals. Methods

This was a retrospective, observational study of treatment-na•ve HIV-infected individuals managed at the 550 clinic who started antiretroviral therapy (ART) between January 1st, 2010 and December 31, 2015. Patients with available viral load and CD4 counts before and one year after initiating ART were included in this study. Virologic suppression was defined as < 48 HIV-1 RNA copies/mL, and mmunologic recovery was defined as a CD4 count increase of at least 150 cells/mm3. Dichotomous variables were reported in number and percentages and analyzed using Chi-squared tests and Fisher’s exact (whichever was appropriate). Continuous variables were reported as median and interquartile range (IQR) and analyzed using Wilcox rank-sum tests. Multivariate analyses performed were logistic regressions with adjustment for other covariates. P value <0.05 was considered statistically significant. R version 3.3.2 was used for the statistical analysis. Results

A total of 70 women and 90 men were included …


Level Of Exposure Of Childhood Tuberculosis With Adult Pulmonary Tuberculosis Household Contacts, Al Asyary, Tris Eryando, Purwantyastuti Purwantyastuti, Purnawan Junadi, Carol Clark, Edwin Van Teijlingen Aug 2017

Level Of Exposure Of Childhood Tuberculosis With Adult Pulmonary Tuberculosis Household Contacts, Al Asyary, Tris Eryando, Purwantyastuti Purwantyastuti, Purnawan Junadi, Carol Clark, Edwin Van Teijlingen

Kesmas

Tuberkulosis paru (TB) pada anak kian menjadi masalah kesehatan global yang masih terlupakan seiring dengan peningkatan proporsi TB di Indonesia. Penularan penyakit ini di populasi umum seringkali berdampak pada anak, terlebih ketika kontak TB terjadi di rumah tangga. Penelitian ini bertujuan untuk memperoleh faktor protektif sehingga anak tetap sehat meskipun memiliki kontak dengan penderita TB dewasa serumah. Penelitian ini dilakukan dengan pendekatan kasus kontrol pada 132 responden anak yang berasal dari delapan rumah sakit rujukan dan beberapa puskesmas di Provinsi Daerah Istimewa Yogyakarta. Penelitian dilakukan dalam periode Januari hingga Desember 2014 yang hasilnya dianalisis dengan uji bivariat (kai kuadrat) dan …


Bancroftian Filariasis Transmission Parameters After The Fifth Year Of Filiariasis Mass Drug Administration In Pekalongan City, Tutik Ida Rosanti, Sugeng Juwono Mardihusodo, Wayan Artama Aug 2017

Bancroftian Filariasis Transmission Parameters After The Fifth Year Of Filiariasis Mass Drug Administration In Pekalongan City, Tutik Ida Rosanti, Sugeng Juwono Mardihusodo, Wayan Artama

Kesmas

Penelitian ini bertujuan untuk mengukur parameter parasitologi (microfilaria rate, kepadatan mikrofilaria), parameter imunologi (antigen prevalence) dan parameter entomologi (infection rate dan infective rate) pada tahun kelima pelaksanaan mass drug administration di Kelurahan Pabean Kota Pekalongan. Penelitian ini merupakan penelitian observasional dengan pendekatan potong lintang yang dilaksanakan pada bulan Juli sampai dengan Agustus 2015 di Kelurahan Pabean Kota Pekalongan. Microfilaria rate dan kepadatan mikrofilaria ditentukan dengan pemeriksaan darah jari pada 313 responden. Antigen prevalence ditentukan dengan mengukur antigen beredar menggunakan metode immunochromatographic test (ICT) Wuchereria bancrofti. Incective rate dan infection rate diukur dengan cara menemukan larva cacing filaria pada nyamuk hasil …


Provision Of Informed Consent Towards The Level Of Anxiety In Pre-Operative Patients At Mamuju District Public Hospital, Imelda Appulembang Aug 2017

Provision Of Informed Consent Towards The Level Of Anxiety In Pre-Operative Patients At Mamuju District Public Hospital, Imelda Appulembang

Kesmas

Tindakan pembedahan merupakan salah satu tindakan medis yang dapat mendatangkan stressor sehingga menimbulkan kecemasan pada pasien. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian informed consent terhadap tingkat kecemasan pada pasien pra-operasi di Rumah Sakit Umum Daerah (RSUD) Mamuju. Populasi pada penelitian ini adalah pasien pra-operasi. Sampel ditentukan dengan menggunakan pendekatan accidental sampling sehingga diperoleh sampel sebanyak 32 orang. Jenis penelitian ini adalah penelitian kuantitatif dengan menggunakan metode quasi experimental design melalui pendekatan non-equivalent time sample design yang dianalisis dengan menggunakan uji statistik Wilcoxon. Hasil penelitian menunjukkan bahwa terdapat pengaruh pemberian informed consent terhadap tingkat kecemasan pasien. Dapat disimpulkan pemberian informed …


Risk Differences Between Elderly Men And Women Toward Doctor-Diagnosed Diabetes Mellitus In Urban Areas In Indonesia: 2013 National Basic Health Research Data, Meiwita Budiharsana Aug 2017

Risk Differences Between Elderly Men And Women Toward Doctor-Diagnosed Diabetes Mellitus In Urban Areas In Indonesia: 2013 National Basic Health Research Data, Meiwita Budiharsana

Kesmas

Diabetes melitus (DM) adalah salah satu penyakit tidak menular yang paling umum di Indonesia. DM disebabkan berbagai faktor risiko. Peningkatan prevalensi DM salah satunya disebabkan oleh perubahan gaya hidup di perkotaan. Penelitian ini bertujuan untuk menguji perbedaan prevalensi DM yang didiagnosis dokter pada laki-laki dan perempuan usia 15 tahun keatas yang tinggal di daerah perkotaan di Indonesia. Analisis menggunakan data sekunder Riset Kesehatan Dasar (Riskesdas) 2013 dengan desain studi potong lintang. Total sampel sebanyak 333.731 responden. Metode analisis menggunakan regresi logistik ganda. Hasil menunjukkan bahwa DM yang didiagnosis dokter pada laki-laki dan perempuan usia 15-39 tahun di perkotaan tidak berbeda. …


Influence Of Quality Of Work Life Towards Psychological Well-Being And Turnover Intention Of Nurses And Midwives In Hospital, Indra Wahju Hardjanti, Aryo Dewanto, Noermijati Noermijati Aug 2017

Influence Of Quality Of Work Life Towards Psychological Well-Being And Turnover Intention Of Nurses And Midwives In Hospital, Indra Wahju Hardjanti, Aryo Dewanto, Noermijati Noermijati

Kesmas

Selama ini perawat telah dilatih untuk memberikan perawatan pasien dan meningkatkan kualitas hidup pasien, namun kualitas kehidupan kerja dan psychological well-being mereka sendiri terabaikan. Rendahnya kualitas kehidupan kerja perawat di rumah sakit menyebabkan tingginya keinginan pindah kerja perawat. Tingginya angka keinginan pindah kerja perawat dan bidan di Rumah Sakit X Malang merupakan masalah yang memerlukan perhatian dari manajemen rumah sakit agar tidak menjadi menyebabkan rendahnya mutu pelayanan kesehatan di rumah sakit. Penelitian ini bertujuan untuk mengetahui hubungan antara kualitas kehidupan kerja, psychological well-being, dan keinginan pindah kerja perawat dan bidan di rumah sakit. Penelitian ini menggunakan desain penelitian kuantitatif korelasional …


Influence Of Scaling Up Nutrition Education Towards Knowledge And Attitude Of Students At Santa Elisabeth Medan School Of Health Sciences, Rani Gartika Holivia Silalahi, Yesschi Anggraeni Tambunan Aug 2017

Influence Of Scaling Up Nutrition Education Towards Knowledge And Attitude Of Students At Santa Elisabeth Medan School Of Health Sciences, Rani Gartika Holivia Silalahi, Yesschi Anggraeni Tambunan

Kesmas

Tingginya angka pernikahan pada usia remaja yang disertai dengan rendahnya pengetahuan tentang pola asuh merupakan salah satu pemicu terjadinya masalah gizi. Remaja merupakan orang tua masa depan. Tujuan penelitian ini untuk mengetahui pengaruh pendidikan 1.000 hari pertama kehidupan terhadap pengetahuan dan sikap mahasiswi Sekolah Tinggi Ilmu Kesehatan Santa Elisabeth Medan tahun 2016. Penelitian ini menggunakan kuasi eksperimental dengan desain one group pre- dan post test. Metode pengambilan sampel dengan metode purposive sampling sebanyak 115 mahasiswi tingkat III program studi Diploma III Kebidanan. Pendidikan dilakukan di kelas sebanyak 4 kali dalam 2 minggu dengan menggunakan metode mengajar dan diskusi. Penelitian ini …


Effects Of Contraceptive Use On Productivity Of Women Labor At Pt. Bomar Makassar Industrial Area, Masni Mappajanci, Andi Misnawati, Darmawansyah Darmawansyah Aug 2017

Effects Of Contraceptive Use On Productivity Of Women Labor At Pt. Bomar Makassar Industrial Area, Masni Mappajanci, Andi Misnawati, Darmawansyah Darmawansyah

Kesmas

Produktivitas kerja potensial pada kelangsungan hidup perusahaan. Penggunaan kontrasepsi dapat memengaruhi fisiologi setiap perempuan, sehingga dapat memengaruhi aktivitas sehari-hari dan akan berdampak terhadap produktivitas tenaga kerja. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan alat kontrasepsi terhadap produktivitas tenaga kerja perempuan dengan mengontrol usia, pendidikan dan motivasi kerja. Penelitian dengan rancangan potong lintang melibatkan 71 pekerja perempuan PT Bomar Makassar yang telah menikah. Pengumpulan data dilakukan dengan wawancara menggunakan kuesioner pada bulan Mei sampai Juni 2015, kemudian dianalisis secara univariat, bivariat, dan multivariat. Hasil penelitian menunjukkan bahwa terdapat pengaruh penggunaan alat kontrasepsi terhadap produktivitas kerja setelah dikontrol dengan variabel usia (nilai …


The Profile And Determinant Factors Of Quality Of Life In Patients With Diabetic Neuropathy, Rizaldy Taslim Pinzon, Kadek Sinthia Grahita Adnyana, Marta Lisnawati Zalukhu Aug 2017

The Profile And Determinant Factors Of Quality Of Life In Patients With Diabetic Neuropathy, Rizaldy Taslim Pinzon, Kadek Sinthia Grahita Adnyana, Marta Lisnawati Zalukhu

Kesmas

Neuropati merupakan salah satu komplikasi tersering pada diabetes melitus (DM). Neuropati dapat memengaruhi kualitas hidup, derajat kesehatan, maupun tingkat ekonomi. Oleh karena itu, penting untuk mengetahui kualitas hidup pasien DM dengan neuropati beserta dampak yang ditimbulkannya terlebih dahulu agar mendapatkan penanganan yang tepat demi meningkatkan kualitas hidup pasien. Penelitian ini bertujuan untuk mengetahui profil kualitas hidup pasien DM dengan neuropati. Penelitian ini merupakan studi observasional menggunakan Short Form 8 (SF-8) Health Survey Standard Indonesia terhadap pasien diabetes melitus dengan neuropati yang diambil secara konsekutif pada bulan Maret hingga Agustus 2016 di Poli Saraf Rumah Sakit Bethesda, Yogyakarta. Terdapat 57 subjek …


Interleukin-6 (Il-6) Rs1800796 And Cyclin Dependent Kinase Inhibitor (Cdkn2a/Cdkn2b) Rs2383207 Are Associated With Ischemic Stroke In Indigenous West African Men, Rufus Akinyemi, Donna K. Arnett, Hemant K. Tiwari, Bruce Ovbiagele, Fred Sarfo, Vinodh Srinivasasainagendra, Marguerite Ryan Irvin, Abiodun Adeoye, Rodney T. Perry, Albert Akpalu, Carolyn Jenkins, Lukman Owolabi, Reginald Obiako, Kolawole Wahab, Emmanuel Sanya, Morenikeji Komolafe, Michael Fawale, Philip Adebayo, Godwin Osaigbovo, Taofiki Sunmonu, Paul Olowoyo, Innocent Chukwuonye, Yahaya Obiabo, Onoja Akpa, Sylvia Melikam, Raelle Saulson, Raj Kalaria, Adesola Ogunniyi, Mayowa Owolabi Aug 2017

Interleukin-6 (Il-6) Rs1800796 And Cyclin Dependent Kinase Inhibitor (Cdkn2a/Cdkn2b) Rs2383207 Are Associated With Ischemic Stroke In Indigenous West African Men, Rufus Akinyemi, Donna K. Arnett, Hemant K. Tiwari, Bruce Ovbiagele, Fred Sarfo, Vinodh Srinivasasainagendra, Marguerite Ryan Irvin, Abiodun Adeoye, Rodney T. Perry, Albert Akpalu, Carolyn Jenkins, Lukman Owolabi, Reginald Obiako, Kolawole Wahab, Emmanuel Sanya, Morenikeji Komolafe, Michael Fawale, Philip Adebayo, Godwin Osaigbovo, Taofiki Sunmonu, Paul Olowoyo, Innocent Chukwuonye, Yahaya Obiabo, Onoja Akpa, Sylvia Melikam, Raelle Saulson, Raj Kalaria, Adesola Ogunniyi, Mayowa Owolabi

Epidemiology and Environmental Health Faculty Publications

Background—Inherited genetic variations offer a possible explanation for the observed peculiarities of stroke in sub – Saharan African populations. Interleukin–6 polymorphisms have been previously associated with ischemic stroke in some non-African populations.

Aim—Herein we investigated, for the first time, the association of genetic polymorphisms of IL-6 and CDKN2A- CDKN2B and other genes with ischemic stroke among indigenous West African participants in the Stroke Investigative Research and Education Network (SIREN) Study.

Methods—Twenty-three previously identified single nucleotide polymorphisms (SNPs) in 14 genes of relevance to the neurobiology of ischemic stroke were investigated. Logistic regression models adjusting for known …


Determinant Of Timely First-Shot Hepatitis B Immunization In East Lombok, West Nusa Tenggara, Indonesia, Putri Bungsu Machmud, Dwi Gayatri, Tri Yunis Miko Wahyono Jul 2017

Determinant Of Timely First-Shot Hepatitis B Immunization In East Lombok, West Nusa Tenggara, Indonesia, Putri Bungsu Machmud, Dwi Gayatri, Tri Yunis Miko Wahyono

Jurnal Epidemiologi Kesehatan Indonesia

Hepatitis B remains as one of health problems in the world. The results of several studies related to factors in predicting of the timely first-shot hepatitis B immunization were still inconsistent. Aim of this study is to identify determinant factors of the timely first-shot hepatitis B immunization in East Lombok, Indonesia. We used a cross sectional design study, and data derived from immunization coverage survey at six districts/ cities in 2013. A Total of 227 children aged 12 to 23 months who already got immunization of a first-shot hepatitis B vaccineand well documented were included as samples in this study. …


Pengaruh Konsumsi Fruktosa Pada Minuman Kemasan Terhadap Toleransi Glukosa Terganggu Pada Kelompok Usia Muda Di Perkotaan Di Indonesia, Nicolaski Lumbuun, Nasrin Kodim Jul 2017

Pengaruh Konsumsi Fruktosa Pada Minuman Kemasan Terhadap Toleransi Glukosa Terganggu Pada Kelompok Usia Muda Di Perkotaan Di Indonesia, Nicolaski Lumbuun, Nasrin Kodim

Jurnal Epidemiologi Kesehatan Indonesia

Peningkatan konsumsi minuman kemasan (soft drinks/ bevereges) tampak nyata di dunia, termasuk Indonesia. Peningkatan ini terutama terjadi di kelompok usia muda. Konsumsi minuman tersebut berkaitan dengan gangguan metabolik, antara lain obesitas, toleransi glukosa terganggu (TGT) dan diabetes melitus. Hal ini disebabkan penggunaan pemanis tinggi fruktosa (high fructose corn syrup, HFCS). TGT terutama menjadi masalah kesehatan serius karena umumnya tidak menunjukkan gejala dan terlambat untuk dideteksi sehingga sering kali telah berprogresi menjadi diabetes mellitus. Penelitian ini bertujuan untuk melihat hubungan konsumsi tinggi fruktosa dengan kejadian TGT pada usia muda, serta prevalensi kekerapan mengkonsumsi minuman tinggi fruktosa, baik secara nasional maupun pada …


Hubungan Obesitas Dengan Kejadian Hipertensi Derajat 1 Di Pos Pembinaan Terpadu Penyakit Tidak Menular (Posbindu Ptm) Kantor Kesehatan Pelabuhan Bandung Tahun 2016, Teguh Dhika Rohkuswara, Syahrizal Syarif Jul 2017

Hubungan Obesitas Dengan Kejadian Hipertensi Derajat 1 Di Pos Pembinaan Terpadu Penyakit Tidak Menular (Posbindu Ptm) Kantor Kesehatan Pelabuhan Bandung Tahun 2016, Teguh Dhika Rohkuswara, Syahrizal Syarif

Jurnal Epidemiologi Kesehatan Indonesia

Hipertensi sampai saat ini masih menjadi masalah kesehatan di dunia termasuk Indonesia. Prevalensi hipertensi di Indonesia, cukup tinggi yaitu sebesar 25,8% (Riskesdas, 2013). Sebagian besar penderita hipertensi termasuk dalam kelompok hipertensi derajat 1 dan separuhnya tidak menyadari sebagai penderita. Hipertensi bukan penyakit kausal tunggal, ada berbagai faktor yang berkontribusi terhadap munculnya hipertensi, salah satunya yang sering ditemukan adalah obesitas. Penelitian ini bertujuan untuk mengetahui besarnya hubungan antara obesitas dengan kejadian hipertensi derajat 1 di Posbindu PTM Kantor Kesehatan Pelabuhan Bandung. Desain penelitian adalah cross sectional, menggunakan data sekunder kegiatan Posbindu PTM KKP Bandung tahun 2016. Subjek penelitian adalah pegawai instansi …


Pengaruh Jarak Kelahiran Terhadap Kematian Bayi Di Indonesia, Filipina, Dan Kamboja (Analisis Data Survei Demografi Kesehatan), Adelina Fitri, Asri Adisasmita, Renti Mahkota Jul 2017

Pengaruh Jarak Kelahiran Terhadap Kematian Bayi Di Indonesia, Filipina, Dan Kamboja (Analisis Data Survei Demografi Kesehatan), Adelina Fitri, Asri Adisasmita, Renti Mahkota

Jurnal Epidemiologi Kesehatan Indonesia

Kematian bayi didefinisikan sebagai kematian yang terjadi pada tahun pertama kehidupan. Angka kematian bayi di Indonesia dan Kamboja sendiri masih berada diatas AKB Asia Tenggara, sedangkan Filipina sudah sama dengan AKB Asia Tenggara. Jarak kelahiran merupakan salah satu faktor yang memegang peran penting pada kematian bayi. Tujuan penelitian ini adalah untuk mengetahui pengaruh jarak kelahiran terhadap kematian bayi di Indonesia, Filipina dan Kamboja. Penelitian menggunakan data dari Demographic Health Survey (DHS). Desain penelitian adalah cross sectional dan sampel pada masing-masing negara berjumlah 10.162, 4.741 dan 4.330 bayi. Hasil penelitian memperlihatkan, jarak kelahiran < 18 bulan memiliki risiko paling besar terhadap kematian bayi di Indonesia (OR = 2,43: 95% CI 1,26 - 4,70), Kamboja (OR = 4,39: 95% CI 1,76 - 10,94) dibandingkan jarak kelahiran 18 - 23 bulan, 24 - 35 bulan dan > 36 bulan. Sedangkan di Filipina jarak kelahiran 18 …


Feeding Problems Sebagai Prediktor Kejadian Obestitas Pada Anak Autis, Qisty Afifah Noviyanti Jul 2017

Feeding Problems Sebagai Prediktor Kejadian Obestitas Pada Anak Autis, Qisty Afifah Noviyanti

Jurnal Epidemiologi Kesehatan Indonesia

Latar belakang: Obesitas merupakan masalah yang dapat terjadi pada anak autis. Hal ini disebabkan adanya perubahan perilaku dan pola makan akibat kondisi autisme. Akan tetapi, belum banyak studi yang menjelaskan hubungan perilaku makan bermasalah (feeding problems) dengan kejadian obesitas pada anak autis. Tujuan: Penelitian ini untuk melihat hubungan antara masalah perilaku makan (feeding problem) dengan kejadian obesitas anak autis. Metode: Peninjauan artikel dilakukan dengan kata kunci autism OR autism spectrum disorder AND feeding problem OR food selectivity dan autism AND childhood obesity. Dua studi ditemukan sesuai dengan kriteria inklusi yang dibuat Anak autis memiliki perilaku makan bermasalah yang lebih tinggi …


Prediktor Kejadian Tb Pada Odha Di Salah Satu Rs Pemerintah Bogor, Tahun 2014-2016, Ulya Qoulan Karima, Mondastri Korib Sudaryo, Nuning Maria Kiptiyah Jul 2017

Prediktor Kejadian Tb Pada Odha Di Salah Satu Rs Pemerintah Bogor, Tahun 2014-2016, Ulya Qoulan Karima, Mondastri Korib Sudaryo, Nuning Maria Kiptiyah

Jurnal Epidemiologi Kesehatan Indonesia

TB merupakan tantangan bagi pengendalian Acquired Immunodeficiency Syndrome (AIDS) karena merupakan infeksi oportunistik terbanyak pada orang dengan HIV/AIDS (ODHA). TB dapat meningkatkan progresivitas HIV dan meningkatkan risiko kematian bagi penderita HIV. Tujuan penelitian ini adalah untuk mengetahui prediktor yang berhubungan dengan kejadian TB pada ODHA di salah satu RS tahun 2014-2016. Desain studi yang digunakan adalah cross sectional dengan menggunakan data register ART dan Rekam Medis. Sampel berjumlah 817 pasien HIV. Analisis data dilakukan dengan menggunakan multiple cox regression. Hasil analisis multivariat menunjukkan adanya peningkatan risiko TB pada kelompok dengan anemia (PR=1,54, 95% CI: 1,17-2,03) dibandingkan kelompok tanpa anemia, adanya …