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Articles 1 - 30 of 43
Full-Text Articles in Life Sciences
Pharyngeal Constriction As A Cause For Late Acquisition And Speech Sound Disorders Of Rhotic Sounds In English, Spanish, And French, Connor Mahon
The Downtown Review
This paper attempts to explain why rhotic sounds are cross-linguistically late developing among the sound inventory of children. Included is a summary of the current literature regarding classification of rhotic sounds, an examination of the articulatory movement of the tongue root, and an overview of the clinical implications on the field of speech-language pathology. The evidence presented supports the hypothesis that pharyngeal constriction is characteristic of rhotic sounds in many languages, and that it is related to the relative late acquisition and higher rate of speech sound disorders, as seen in English, Spanish, and French.
Biophysical And Biomechanical Properties Of Neural Progenitor Cells As Indicators Of Developmental Neurotoxicity, Gautam Mahajan, Moo-Yeal Lee, Chandrasekhar R. Kothapalli
Biophysical And Biomechanical Properties Of Neural Progenitor Cells As Indicators Of Developmental Neurotoxicity, Gautam Mahajan, Moo-Yeal Lee, Chandrasekhar R. Kothapalli
Chemical & Biomedical Engineering Faculty Publications
Conventional in vitro toxicity studies have focused on identifying IC50 and the underlying mechanisms, but how toxicants influence biophysical and biomechanical changes in human cells, especially during developmental stages, remain understudied. Here, using an atomic force microscope, we characterized changes in biophysical (cell area, actin organization) and biomechanical (Young's modulus, force of adhesion, tether force, membrane tension, tether radius) aspects of human fetal brain-derived neural progenitor cells (NPCs) induced by four classes of widely used toxic compounds, including rotenone, digoxin, N-arachidonoylethanolamide (AEA), and chlorpyrifos, under exposure up to 36 h. The sub-cellular mechanisms (apoptosis, mitochondria membrane potential, DNA damage, glutathione …
An Examination Of The Death Penalty, Alexandra N. Kremer
An Examination Of The Death Penalty, Alexandra N. Kremer
The Downtown Review
The death penalty, or capital punishment, is the use of execution through hanging, beheading, drowning, gas chambers, lethal injection, and electrocution among others in response to a crime. This has spurred much debate on whether it should be used for reasons such as ethics, revenge, economics, effectiveness as a deterrent, and constitutionality. Capital punishment has roots that date back to the 18th century B.C., but, as of 2016, has been abolished in law or practice by more than two thirds of the world’s countries and several states within the United States. Here, the arguments for and against the death …
A Synthesis Platform For Temperature Responsive Star Polymers, Schmitt J. Richard Jr.
A Synthesis Platform For Temperature Responsive Star Polymers, Schmitt J. Richard Jr.
ETD Archive
Star polymers are a class of branched polymers comprised of several polymer chains extending from a central point. Star polymers have applications in biopharmaceuticals where they have been proposed to be suitable drug delivery vehicles. Star polymers have traditionally been synthesized through chemical synthesis with added functionality provided by grafting on the arms. This complex synthesis can be simplified by using a biosynthetic approach which enables precise control of molecular weight and composition. This approach is demonstrated using star polymers with arms composed of a temperature responsive protein-based polymer termed elastin-like polypeptide (ELP). Star polymers are characterized based on the …
Real-Time Assessment And Visual Feedback For Patient Rehabilitation Using Inertial Sensors, Deepa Adinarayanan
Real-Time Assessment And Visual Feedback For Patient Rehabilitation Using Inertial Sensors, Deepa Adinarayanan
ETD Archive
Rehabilitation exercises needs have been continuously increasing and have been projected to increase in future as well based on its demand for aging population, recovering from surgery, injury and illness and the living and working lifestyle of the people. This research aims to tackle one of the most critical issues faced by the exercise administers-Adherence or Non-Adherence to Home Exercise problems especially has been a significant issue resulting in extensive research on the psychological analysis of people involved. In this research, a solution is provided to increase the adherence of such programs through an automated real-time assessment with constant visual …
Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag
Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag
ETD Archive
Kidney cyst expansion, stagnant fluid accumulation, and insufficient vascular supply can result in localized chronic ischemia-hypoxia in kidney cysts, as well as in normal renal epithelia adjacent to a cyst. We hypothesize that in normal epithelia near a cyst, the stabilization of Hypoxia Inducible Factor 1a (HIF1a), a major regulator of cellular response to hypoxia, can cause altered paracellular and transcellular transport, transforming a normal absorptive phenotype to a secretory and paracellularly leaky phenotype, leading to cyst expansion. Using 100 µmol/L cobalt chloride (CoCl2), HIF1a was stabilized in cellular nucleus of a mouse cortical collecting duct cell line (mCCD 1296 …
Jainism And Nonviolence: From Mahavira To Modern Times, Lana E. Sims
Jainism And Nonviolence: From Mahavira To Modern Times, Lana E. Sims
The Downtown Review
The research contained in this paper focuses on the religion of Jainism, its main principle of ahimsa, or nonviolence, and how that philosophy has evolved over the years, eventually inspiring today’s nonviolent movements. First, a look will be taken at the origin of Jainism, with a brief explanation of its most important principles and beliefs. Then, ahimsa is explained as it has been traditionally perceived by Jains. The recent evolution of the meaning of ahimsa and its impact on modern nonviolence movements is discussed, with a focus on the influence of second-generation Jains in the United States on the …
Life Behind Glass: Bioreactor Studies On The Salt-Water Adaptation Of Scenedesmus Dimorphus, Joshua Hartranft, Alex Fedai, Sahar Ataya
Life Behind Glass: Bioreactor Studies On The Salt-Water Adaptation Of Scenedesmus Dimorphus, Joshua Hartranft, Alex Fedai, Sahar Ataya
Undergraduate Research Posters 2016
Algae has considerable promise as source for liquid biofuel because of high productivity and because algae farms do not compete with food crops for arable land. Freshwater algae is preferred over saltwater algae because of the higher lipid content in the former. Unfortunately, freshwater algae “farms” would require a vast amount of fresh water, and given the scarcity of fresh water, this is not a viable long-term solution. Therefore, the adaption of a fresh-water species of algae to a salt-water environment is a potential solution. In this study, it was shown that the growth rate of the freshwater algae S. …
Glycerolipid Analysis Of Adaptation To Saline Changes In The Culture Conditions Of Algae, Scenedesmus Dimorphus, By Gc-Ms, Tyler Fitzgerald, Satya Girish Chandra Avula, Chandana Mannem
Glycerolipid Analysis Of Adaptation To Saline Changes In The Culture Conditions Of Algae, Scenedesmus Dimorphus, By Gc-Ms, Tyler Fitzgerald, Satya Girish Chandra Avula, Chandana Mannem
Undergraduate Research Posters 2016
Since fossil fuels are decreasing over time an alternative energy source will be soon required. The algae, Scenedesmus dimorphus, grows in freshwater and is known for its fast growth of glycerolipid content which is used for biodiesel production. After the algae is grown in optimal conditions, the released fatty acids and glycerolipids are transformed into fatty acid methyl esters (FAMEs) which are used as biodiesel. The FAMEs were quantitatively determined by gas chromatography mass spectrometry (GC-MS) to determine the total glycerolipid content in the different algae samples. The samples that were analyzed include freshwater controls and saline adapted samples. Analysis …
Design And Fabrication Of A Microfluidic Device Using A 3d Printer, Aaron Smith
Design And Fabrication Of A Microfluidic Device Using A 3d Printer, Aaron Smith
Undergraduate Research Posters 2016
The goal of this work was to design and implement a microfluidic mixer-based chemical reactor using a 3-D printer. Microfluidic devices are very useful for processes that use expensive reactants or require a high level of control, and we hypothesize that the ability to develop a prototype using a 3-D printer would lower their costs and help overcome some of the limitations of soft-lithography based devices. One-level and two-level designs were made using SolidWorks® software, and various stages of the model were printed on Objet® and FDM® printers. The Objet printer offers the advantage of printing a prototype using a …
Scalable Assembly Of Nanoparticles Onto Templated Substrates, John Juchnowski
Scalable Assembly Of Nanoparticles Onto Templated Substrates, John Juchnowski
Undergraduate Research Posters 2016
Anisotropic nanoparticles, such as carbon nanotubes and noble metal nanorods, have excellent electrical, mechanical, and thermal properties. This work examined techniques for the nanopatterning of silicon substrates for the subsequent deposition of anisotropic nanoparticles in order to exploit their properties in macroscopic applications. Argon-ion-sputter induced rippling of Si (100) as well as a microparticle mask were examined as methods for templating a silicon substrate. For the ion-sputter
Light Scattering Characterization Of Elastin-Like Polypeptide Trimer Micelles, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Light Scattering Characterization Of Elastin-Like Polypeptide Trimer Micelles, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Undergraduate Research Posters 2016
Elastin-Like Polypeptides (ELP) can be used to form thermo-reversible vehicles for drug delivery systems. The ELP nanoparticles are composed of three-armed star polypeptides. Each of the three arms extending from the negatively charged foldon domain includes 20 repeats of the (GVGVP) amino acid sequence. The ELP polymer chains are soluble at room temperature and become insoluble at the transition temperature (close to 50 oC), forming micelles. The size and shape of the micelle is dependent on the temperature and the pH of solution, along with the concentration of the Phosphate Buffered Saline (PBS) solvent. The technique of Depolarized Dynamic Light …
Light Scattering Study Of Mixed Micelles Made From Elastin-Like Polypeptide Linear Chains And Trimers, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Light Scattering Study Of Mixed Micelles Made From Elastin-Like Polypeptide Linear Chains And Trimers, Ilona Tsuper, Daniel Terrano, Adam Maraschky
Undergraduate Research Posters 2016
Temperature sensitive nanoparticles (E20F) were generated from a construct of three chains of Elastin- Like Polypeptides (ELP) linked to a negatively charged foldon domain. This ELP system was mixed at different ratios with a single linear chain of ELP (H40L) which was deprived of the foldon domain. The mixed system is soluble at room temperature and at a transition temperature will form swollen micelles with the hydrophobic linear chains hidden inside. This system was studied using Depolarized Dynamic Light Scattering (DDLS) and Static Light Scattering (SLS) to model the size, shape, and internal structure of the mixed micelles. The mixed …
Identifying Patterns Of Stress Through Biological Markers, Kristyn Oravec
Identifying Patterns Of Stress Through Biological Markers, Kristyn Oravec
Undergraduate Research Posters 2016
technique, the angle of incidence of the ion beam was 67° from the surface normal,
Feasibility And Effects Of Accelerometer Based Feedback On Paretic Upper Extremity Amount Of Use In The Home Setting In Subjects Chronic Post-Stroke, Nathan Pohl, Amber Kuehn, Mishgan Abdullah
Feasibility And Effects Of Accelerometer Based Feedback On Paretic Upper Extremity Amount Of Use In The Home Setting In Subjects Chronic Post-Stroke, Nathan Pohl, Amber Kuehn, Mishgan Abdullah
Undergraduate Research Posters 2015
Purpose : to (1) evaluate the feasibility of using accelerometers in the home to quantify how much subjects chronic post-stroke (PS) use their upper extremities (UE), (2) measure differences between amount of UE movement in subjects PS and a healthy control group (HC), (3) determine the effects of accelerometer based feedback on paretic UE use in subjects PS, and (4) determine if those effects are retained over time. Methods : Six subjects PS wore accelerometers for 3 weeks with two feedback sessions given during week two. Seven HC subjects wore accelerometers for one week. Accelerometer based outcome measures included relative …
Effects Of Accelerometer Based Feedback On Clinical Measures And Paretic Upper Extremity Amount Of Use In Subjects Chronic Post-Stroke, Amber Kuehn, Nathan Pohl, Mishgan Abdullah
Effects Of Accelerometer Based Feedback On Clinical Measures And Paretic Upper Extremity Amount Of Use In Subjects Chronic Post-Stroke, Amber Kuehn, Nathan Pohl, Mishgan Abdullah
Undergraduate Research Posters 2015
Purpose/Hypothesis: To determine the effects of accelerometer based feedback on clinical measures of paretic upper extremity (UE) recovery in people post-stroke and examine the relationship between these changes and paretic UE amount of use (AOU) measured by an accelerometer. Subjects: 7 people chronic post-stroke (5 males, 2 females; aged 62.03 ± 11.33 years) with an Upper Extremity Fugl-Meyer score range of 10-63 were included for this poster. Materials/Methods: Subjects wore wrist accelerometers for 3 weeks in the home. Clinical measures (Motor Activity Log, Stroke Impact Scale, Chedoke Arm and Hand Activity Inventory, and the ABILHAND) were assessed weekly. Data analysis …
Effect Of Accelerometer Based Feedback On Paretic Upper Extremity Amount Of Use And Quality Of Movement: A Case Study, Mishgan Abdullah, Nathan Pohl, Amber Kuehn
Effect Of Accelerometer Based Feedback On Paretic Upper Extremity Amount Of Use And Quality Of Movement: A Case Study, Mishgan Abdullah, Nathan Pohl, Amber Kuehn
Undergraduate Research Posters 2015
Purpose/Hypothesis: To determine the effects of accelerometer based feedback on clinical measures of paretic upper extremity (UE) recovery in people post-stroke and examine the relationship between these changes and paretic UE amount of use (AOU) measured by an accelerometer. Subjects: 7 people chronic post-stroke (5 males, 2 females; aged 62.03 ± 11.33 years) with an Upper Extremity Fugl-Meyer score range of 10-63 were included for this poster. Materials/Methods: Subjects wore wrist accelerometers for 3 weeks in the home. Clinical measures (Motor Activity Log, Stroke Impact Scale, Chedoke Arm and Hand Activity Inventory, and the ABILHAND) were assessed weekly. Data analysis …
Sound And The Moving Image:Critical Characteristics For Spectator Response, Kara Rader, Rafeeq I. Roberts, Matt Egizii, Jeffery Allen
Sound And The Moving Image:Critical Characteristics For Spectator Response, Kara Rader, Rafeeq I. Roberts, Matt Egizii, Jeffery Allen
Undergraduate Research Posters 2013
The prevailing wisdom in the film and video production industries is that audio information outweighs visual information when it comes to spectator responses, but there are few empirical studies to support this claim. In previous research, four critical characteristics of sound have been identified: (1) Music, (2) visual/sound contradictions (defined as sound that is inconsistent with audience expectations based on visual information), (3) multi-channel sound, and (4) sound quality. Building on our previous research into music and film, we have found that many researchers have looked into the question of how music affects emotions (Eschrich et al., 2008; Have, 2008; …
Role Of Programmed Proteolysis During Meiosis, Vincent Matthews, G. Valentin Borner Ph.D.
Role Of Programmed Proteolysis During Meiosis, Vincent Matthews, G. Valentin Borner Ph.D.
Undergraduate Research Posters 2013
Meiosis is the process which forms gametes and spores for reproduction in eukaryotic cells. During the pachytene phase of meiosis I, a protein structure, called the Synaptonemal Complex (SC), forms between homologous chromosomes and creates a scaffold for genetic recombination. In yeast, the Zip1 protein is a major structural component of the SC. At restrictive temperature for meiosis, ZIP1 is required for completion of meiotic divisions. At permissive temperature ZIP1 is required for proper chromosome segregation. We observed that chemical inhibition of the proteasome, with MG132, results in arrest at prophase of meiosis I. Based on these results, we questioned …
Adaptation Of Scenedesmus Dimorphus To Brackish Water, Dustin Bowden, Joanne M. Belovich
Adaptation Of Scenedesmus Dimorphus To Brackish Water, Dustin Bowden, Joanne M. Belovich
Undergraduate Research Posters 2013
Microalgae is a promising biofuel feedstock for replacement of conventional transportation fuels. Microalgae does not require arable land for cultivation, and the biofuel production rate per acre of land is an order of magnitude greater than that needed for crop-based production methods. Though microalgae to biofuel processes are attractive, none have proven commercially successful due to the high costs of algae dewatering. Moreover, the scarcity of fresh water in many parts of the world prevents development of this process because of competition with drinking water supplies. Our lab has developed an efficient dewatering method using an inclined gravity settler. It …
Papaya (Carica Papaya) Seed As A Low-Cost Sorbent For Zinc Removal, Siew-Teng Ong, Shiau-Ping Yip, Pei-Sin Keng, Siew-Ling Lee, Yung-Tse Hung
Papaya (Carica Papaya) Seed As A Low-Cost Sorbent For Zinc Removal, Siew-Teng Ong, Shiau-Ping Yip, Pei-Sin Keng, Siew-Ling Lee, Yung-Tse Hung
Civil and Environmental Engineering Faculty Publications
The potential of using papaya seed as a sorbent for the removal of Zn from aqueous solution was investigated. The sorption characteristics of the sorbent was studied under various experimental conditions, such as pH, contact time, concentration of Zn(II), agitation rate and sorbent’s particle size. The equilibrium data have been studied using Langmuir, Freundlich and Brunauer-Emmett-Teller equations. The best correlation was obtained using Langmuir isotherm with the regression coefficient value of 0.9799 and maximum sorption capacity of 19.88 mg/g. The effective pH for the maximum uptake of Zn(II) was at pH 5.0. An increase in percentage uptake of Zn(II) can …
2011 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Mark Tebeau
2011 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Mark Tebeau
Scholars and Artists Bibliographies
This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Mark Tebeau was the guest speaker
Analysis Of Migration Models Of Biogeography-Based Optimization Using Markov Theory, Haiping Ma, Daniel J. Simon
Analysis Of Migration Models Of Biogeography-Based Optimization Using Markov Theory, Haiping Ma, Daniel J. Simon
Electrical and Computer Engineering Faculty Publications
Biogeography-based optimization (BBO) is a new evolutionary algorithm inspired by biogeography, which involves the study of the migration of biological species between habitats. Previous work has shown that various migration models of BBO result in significant changes in performance. Sinusoidal migration models have been shown to provide the best performance so far. Motivated by biogeography theory and previous results, in this paper a generalized sinusoidal migration model curve is proposed. A previously derived BBO Markov model is used to analyze the effect of migration models on optimization performance, and new theoretical results which are confirmed with simulation results are obtained. …
Blended Biogeography-Based Optimization For Constrained Optimization, Haiping Ma, Daniel J. Simon
Blended Biogeography-Based Optimization For Constrained Optimization, Haiping Ma, Daniel J. Simon
Electrical and Computer Engineering Faculty Publications
Biogeography-based optimization (BBO) is a new evolutionary optimization method that is based on the science of biogeography. We propose two extensions to BBO. First, we propose a blended migration operator. Benchmark results show that blended BBO outperforms standard BBO. Second, we employ blended BBO to solve constrained optimization problems. Constraints are handled by modifying the BBO immigration and emigration procedures. The approach that we use does not require any additional tuning parameters beyond those that are required for unconstrained problems. The constrained blended BBO algorithm is compared with solutions based on a stud genetic algorithm (SGA) and standard particle swarm …
2009 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Michael Schwartz Ph.D.
2009 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Michael Schwartz Ph.D.
Scholars and Artists Bibliographies
This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Michael Schwartz was the honored guest.
2008 Scholars And Artists Bibliography, Rajshehkar G. Javalgi Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
2008 Scholars And Artists Bibliography, Rajshehkar G. Javalgi Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
Scholars and Artists Bibliographies
This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Rajshekhar Javalgi was the guest speaker.
2007 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Joanne E. Goodell Ph.D.
2007 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library, Joanne E. Goodell Ph.D.
Scholars and Artists Bibliographies
This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Joanne Goodell was the guest speaker.
2006 Scholars And Artists Bibliography, Daniel J. Simon, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
2006 Scholars And Artists Bibliography, Daniel J. Simon, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
Scholars and Artists Bibliographies
This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Dan Simon was the guest speaker.
2005 Scholars And Artists Bibliography, Stephen D. Slane Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
2005 Scholars And Artists Bibliography, Stephen D. Slane Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
Scholars and Artists Bibliographies
This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr, Steve Slane was the guest speaker.
2004 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
2004 Scholars And Artists Bibliography, Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library
Scholars and Artists Bibliographies
This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti