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Full-Text Articles in Life Sciences

An Examination Of The Death Penalty, Alexandra N. Kremer Dec 2018

An Examination Of The Death Penalty, Alexandra N. Kremer

The Downtown Review

The death penalty, or capital punishment, is the use of execution through hanging, beheading, drowning, gas chambers, lethal injection, and electrocution among others in response to a crime. This has spurred much debate on whether it should be used for reasons such as ethics, revenge, economics, effectiveness as a deterrent, and constitutionality. Capital punishment has roots that date back to the 18th century B.C., but, as of 2016, has been abolished in law or practice by more than two thirds of the world’s countries and several states within the United States. Here, the arguments for and against ...


Funding Opportunities Specifically For Early Career Unh Investigators: Science, Technology, Engineering, And Math (Stem) – Federal Agencies -- 12.13.18, Lynnette Hentges Dec 2018

Funding Opportunities Specifically For Early Career Unh Investigators: Science, Technology, Engineering, And Math (Stem) – Federal Agencies -- 12.13.18, Lynnette Hentges

Early Career Investigators

This comprehensive list of funding opportunities for early career investigators offered by federal agencies that are appropriate for UNH researchers working in the areas of science, technology, engineering, and math provides information about program focus, eligibility requirements, funding amount and time period, as well as deadlines and links to program web sites and application instructions.

Opportunities available from the National Institutes of Health (NIH) are listed separately.


Elaia 2018, Stephen Case Dec 2018

Elaia 2018, Stephen Case

ELAIA

Over the years, the Program has continued to grow and flourish, and the depth of its research continues to increase. This inaugural journal represents the fruits of that development, containing capstone research projects from the 2018 Honors Program senior class and their faculty mentors. The Table of Contents is diverse, and in that way it is a crystal clear reflection of our program’s community of scholars.

I, along with the members of the Honors Council, am gratified by the work of each student and faculty mentor printed within these pages. Congratulations, everyone!

- Stephen Lowe, Honors Program Director


Quantification Of Voc Emissions From Carbonized Refuse-Derived Fuel Using Solid-Phase Microextraction And Gas Chromatography-Mass Spectrometry, Andrzej Białowiec, Monika Micuda, Antoni Szumny, Jacek Łyczko, Jacek A. Koziel Dec 2018

Quantification Of Voc Emissions From Carbonized Refuse-Derived Fuel Using Solid-Phase Microextraction And Gas Chromatography-Mass Spectrometry, Andrzej Białowiec, Monika Micuda, Antoni Szumny, Jacek Łyczko, Jacek A. Koziel

Agricultural and Biosystems Engineering Publications

In this work, for the first time, the volatile organic compound (VOC) emissions from carbonized refuse-derived fuel (CRDF) were quantified on a laboratory scale. The analyzed CRDF was generated from the torrefaction of municipal waste. Headspace solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS) was used to identify 84 VOCs, including many that are toxic, e.g., derivatives of benzene or toluene. The highest emissions were measured for nonanal, octanal, and heptanal. The top 10 most emitted VOCs contributed to almost 65% of the total emissions. The VOC mixture emitted from torrefied CRDF differed from that emitted by other types ...


Community-Scale Water Treatment Systems In The Dominican Republic, Jonathan Racey, Annabelle Papai, Elise Fischer, Becca Johnson Dec 2018

Community-Scale Water Treatment Systems In The Dominican Republic, Jonathan Racey, Annabelle Papai, Elise Fischer, Becca Johnson

Engagement & Service-Learning Summit: Connecting Through Listening & Scholarship

Engagement and Service-Learning Summit: Reciprocal and Sustainable Partnerships


Analyzing Large Workers’ Compensation Claims Using Generalized Linear Models And Monte Carlo Simulation, Fatemeh Davoudi Kakhki, Steven A. Freeman, Gretchen A. Mosher Dec 2018

Analyzing Large Workers’ Compensation Claims Using Generalized Linear Models And Monte Carlo Simulation, Fatemeh Davoudi Kakhki, Steven A. Freeman, Gretchen A. Mosher

Agricultural and Biosystems Engineering Publications

Insurance practitioners rely on statistical models to predict future claims in order to provide financial protection. Proper predictive statistical modeling is more challenging when analyzing claims with lower frequency, but high costs. The paper investigated the use of predictive generalized linear models (GLMs) to address this challenge. Workers’ compensation claims with costs equal to or more than US$100,000 were analyzed in agribusiness industries in the Midwest of the USA from 2008 to 2016. Predictive GLMs were built with gamma, Weibull, and lognormal distributions using the lasso penalization method. Monte Carlo simulation models were developed to check the performance ...


Automatic Identification Of Animals In The Wild: A Comparative Study Between C-Capsule Networks And Deep Convolutional Neural Networks., Joel Kamdem Teto, Ying Xie Nov 2018

Automatic Identification Of Animals In The Wild: A Comparative Study Between C-Capsule Networks And Deep Convolutional Neural Networks., Joel Kamdem Teto, Ying Xie

Master of Science in Computer Science Theses

The evolution of machine learning and computer vision in technology has driven a lot of

improvements and innovation into several domains. We see it being applied for credit decisions, insurance quotes, malware detection, fraud detection, email composition, and any other area having enough information to allow the machine to learn patterns. Over the years the number of sensors, cameras, and cognitive pieces of equipment placed in the wilderness has been growing exponentially. However, the resources (human) to leverage these data into something meaningful are not improving at the same rate. For instance, a team of scientist volunteers took 8.4 ...


The Development Of Hybrid Lipid-Polymer Nanoparticle Architectures For The Sustained-Release Of Small Hydrophilic Molecules, Keegan Curry, Jill M. Steinbach-Rankins Dr. Nov 2018

The Development Of Hybrid Lipid-Polymer Nanoparticle Architectures For The Sustained-Release Of Small Hydrophilic Molecules, Keegan Curry, Jill M. Steinbach-Rankins Dr.

Posters-at-the-Capitol

Introduction: Polymeric nanoparticles (NPs) have been utilized as drug delivery vehicles for a variety of applications. However, achieving sustained-release of small hydrophilic agents is a primary challenge for their use in prolonged delivery applications.

Objective: This study investigates how novel lipid-polymer hybrid particle architectures can be used to improve the release profile of small hydrophilic encapsulants. Here, PLGA NPs were produced via electrospraying and emulsions. Particles with a core-shell architecture were produced via coaxial electrospraying and the ability of this architecture to sustain release was examined. In addition, we combined polymeric core-shell NPs with a lipid coating to improve biocompatibility ...


Funding Opportunities Specifically For Early Career Unh Investigators: Science, Technology, Engineering, And Math (Stem) – Sponsors Other Than Federal Agencies -- 11.14.18, Lynnette Hentges Nov 2018

Funding Opportunities Specifically For Early Career Unh Investigators: Science, Technology, Engineering, And Math (Stem) – Sponsors Other Than Federal Agencies -- 11.14.18, Lynnette Hentges

Early Career Investigators

This comprehensive list of funding opportunities specifically for early career investigators offered by foundations and other nonprofit sponsors that are appropriate for UNH researchers working in the areas of science, technology, engineering, and math provides information about program focus, eligibility requirements, funding amount and time period, as well as deadlines and links to program web sites and application instructions.


Funding-Opportunities-And-Strategies-For-Early-Career 11.15.18, Lynnette Hentges Nov 2018

Funding-Opportunities-And-Strategies-For-Early-Career 11.15.18, Lynnette Hentges

Early Career Investigators

Slides and handouts from the November 15, 2018 workshop that presented strategies and resources for taking advantage of the special funding opportunities provided to early-career scholars by federal agencies, not-for-profits, professional societies, and other sponsors


Modeling In The Physiology Classroom, Sowmya Anjur Nov 2018

Modeling In The Physiology Classroom, Sowmya Anjur

Faculty Publications & Research

Physiology and Disease is a Biology elective at IMSA that has been developed to be mostly student-centered. Some examples of student projects include modeling heart structure to reflect function and creating LED arduino monitors to measure heart rate. Students also measure their lung capacity and blood pressure to demonstrate correlation of these values with heart rate, and trace the correlation back to neuronal controls. Projects such as these integrate other disciplines such as engineering and conform to NGSS Science and Engineering standards and NGSS Cross cutting Concepts standards. Students take responsibility for their own learning and articulate better on tests.


6 - Evaluating The Effects Of Microenvironment Pro-Inflammatory Cytokines On Breast Cancer Metastasis, Megan Williams Nov 2018

6 - Evaluating The Effects Of Microenvironment Pro-Inflammatory Cytokines On Breast Cancer Metastasis, Megan Williams

Georgia Undergraduate Research Conference (GURC)

Breast cancer is one of the most commonly diagnosed forms of cancer in women, yet there is still no cure for stage IV breast cancer. Stage IV breast cancer is characterized by the cancer becoming metastatic and spreading to other parts of the body. With metastatic breast cancer accounting for approximately 90% of all breast cancer deaths, it is imperative to better understand the mechanisms of breast cancer metastasis for approaches towards treatment and prevention. It is understood that the cellular microenvironment plays a vital role in breast cancer metastasis, as research has shown that signaling molecules, such as cytokines ...


The Santa Clara, 2018-11-01, Santa Clara University Nov 2018

The Santa Clara, 2018-11-01, Santa Clara University

The Santa Clara

No abstract provided.


Classification Of Intensity-Modulated Proton Therapy Plans, Louise Gabrielle Lima '19, Alice Liu '19 Nov 2018

Classification Of Intensity-Modulated Proton Therapy Plans, Louise Gabrielle Lima '19, Alice Liu '19

Student Publications & Research

Proton Radiotherapy

Proton radiotherapy is a form of radiation treatment that uses energized protons to break DNA, leading to cell death and killing cancers.


Emerging Roles Of The Membrane Potential: Action Beyond The Action Potential, Lina Abdul Kadir, Michael Stacey, Richard Barrett-Jolley Nov 2018

Emerging Roles Of The Membrane Potential: Action Beyond The Action Potential, Lina Abdul Kadir, Michael Stacey, Richard Barrett-Jolley

Bioelectrics Publications

Whilst the phenomenon of an electrical resting membrane potential (RMP) is a central tenet of biology, it is nearly always discussed as a phenomenon that facilitates the propagation of action potentials in excitable tissue, muscle, and nerve. However, as ion channel research shifts beyond these tissues, it became clear that the RMP is a feature of virtually all cells studied. The RMP is maintained by the cell's compliment of ion channels. Transcriptome sequencing is increasingly revealing that equally rich compliments of ion channels exist in both excitable and non-excitable tissue. In this review, we discuss a range of critical ...


A Review On Bioconversion Of Agro-Industrial Wastes To Industrially Important Enzymes, Rajeev Ravindran, Shady S. Hassan, Gwilym A. Williams, Amit K, Jaiswal Oct 2018

A Review On Bioconversion Of Agro-Industrial Wastes To Industrially Important Enzymes, Rajeev Ravindran, Shady S. Hassan, Gwilym A. Williams, Amit K, Jaiswal

Articles

Agro-industrial waste is highly nutritious in nature and facilitates microbial growth. Most agricultural wastes are lignocellulosic in nature; a large fraction of it is composed of carbohydrates. Agricultural residues can thus be used for the production of various value-added products, such as industrially important enzymes. Agro-industrial wastes, such as sugar cane bagasse, corn cob and rice bran, have been widely investigated via different fermentation strategies for the production of enzymes. Solid-state fermentation holds much potential compared with submerged fermentation methods for the utilization of agro-based wastes for enzyme production. This is because the physical–chemical nature of many lignocellulosic substrates ...


Micronutrient Availability In Alternative Foods During Agricultural Catastrophes, David C. Denkenberger, Joshua M. Pearce Oct 2018

Micronutrient Availability In Alternative Foods During Agricultural Catastrophes, David C. Denkenberger, Joshua M. Pearce

Department of Materials Science and Engineering Publications

Several catastrophes could block the sun, including asteroid/comet impact, super volcanic eruption, and nuclear war with the burning of cities (nuclear winter). Previous work has analyzed alternate food supplies (e.g., mushrooms growing on dead trees, bacteria growing on natural gas). This was shown to be technically capable of feeding everyone with macronutrients (protein, carbohydrates, and lipids) and minerals, although economics and politics remain uncertain. The present work analyzes vitamin availability in such alternative food scenarios. The vitamin content of various alternate foods is compared to the US recommended daily allowance (RDA) as well as the average requirement defined ...


The Santa Clara, 2018-10-25, Santa Clara University Oct 2018

The Santa Clara, 2018-10-25, Santa Clara University

The Santa Clara

No abstract provided.


D_Luftig_Data_Management_Slides.Pdf, David Luftig Oct 2018

D_Luftig_Data_Management_Slides.Pdf, David Luftig

David Luftig

These are the slides used for 10/24/2018 workshop "Campus Conversation: On-Campus Resources for Federal Grant Seekers."


Optimization Of Time-Weighted Average Air Sampling By Solid-Phase Microextraction Fibers Using Finite Element Analysis Software, Bulat Kenessov, Jacek A. Koziel, Nassiba Baimatova, Olga P. Demyanenko, Miras Derbissalin Oct 2018

Optimization Of Time-Weighted Average Air Sampling By Solid-Phase Microextraction Fibers Using Finite Element Analysis Software, Bulat Kenessov, Jacek A. Koziel, Nassiba Baimatova, Olga P. Demyanenko, Miras Derbissalin

Agricultural and Biosystems Engineering Publications

Determination of time-weighted average (TWA) concentrations of volatile organic compounds (VOCs) in air using solid-phase microextraction (SPME) is advantageous over other sampling techniques, but is often characterized by insufficient accuracies, particularly at longer sampling times. Experimental investigation of this issue and disclosing the origin of the problem is problematic and often not practically feasible due to high uncertainties. This research is aimed at developing the model of the TWA extraction process and optimization of TWA air sampling by SPME using finite element analysis software (COMSOL Multiphysics, Burlington, MA, USA). It was established that sampling by porous SPME coatings with high ...


The Santa Clara, 2018-10-18, Santa Clara University Oct 2018

The Santa Clara, 2018-10-18, Santa Clara University

The Santa Clara

No abstract provided.


The Santa Clara, 2018-10-11, Santa Clara University Oct 2018

The Santa Clara, 2018-10-11, Santa Clara University

The Santa Clara

No abstract provided.


Urban Agriculture And Small Farm Water Use: Case Studies And Trends From Cache Valley, Utah, Tyler Pratt, L. Niel Allen, David E. Rosenberg, Andrew A. Keller, Kelly Kopp Oct 2018

Urban Agriculture And Small Farm Water Use: Case Studies And Trends From Cache Valley, Utah, Tyler Pratt, L. Niel Allen, David E. Rosenberg, Andrew A. Keller, Kelly Kopp

Publications

The landscape of water in Utah is changing due to population growth, conversion of agricultural land to urban development, and increasing awareness of water scarcity. At the same time, Utah is experiencing a growing number of urban and small farms, but knowledge of water use in this sector is limited. Better understanding of what occurs at the field level on urban and small farms can aid state water use estimates and conservation efforts, and assist farmers in moving towards wiser water management. For the 2015 growing season, we performed irrigation evaluations for 24 urban and small farms in Cache Valley ...


The Santa Clara, 2018-10-04, Santa Clara University Oct 2018

The Santa Clara, 2018-10-04, Santa Clara University

The Santa Clara

No abstract provided.


Flexible Laser-Induced Graphene For Nitrogen Sensing In Soil, Nate T. Garland, Eric S. Mclamore, Nicholas D. Cavallaro, Deyny Mendivelso-Perez, Emily A. Smith, Dapeng Jing, Jonathan C. Claussen Oct 2018

Flexible Laser-Induced Graphene For Nitrogen Sensing In Soil, Nate T. Garland, Eric S. Mclamore, Nicholas D. Cavallaro, Deyny Mendivelso-Perez, Emily A. Smith, Dapeng Jing, Jonathan C. Claussen

Mechanical Engineering Publications

Flexible graphene electronics are rapidly gaining interest, but their widespread implementation has been impeded by challenges with ink preparation, ink printing, and post-print annealing processes. Laser-induced graphene (LIG) promises a facile alternative by creating flexible graphene electronics on polyimide substrates through a one-step laser writing fabrication method. Herein we demonstrate the use of LIG, created through a low-cost UV laser, for electrochemical ion selective sensing of plant-available nitrogen (i.e., both ammonium and nitrate ions: NH4+ and NO3-) in soil samples. The laser used to create the LIG was operated at distinct pulse rates (10, 20, 30, 40, and 50 ...


Inference Of Genetic Regulatory Networks With Recurrent Neural Network Models Using Particle Swarm Optimization, Rui Xu, Donald C. Wunsch, Ronald L. Frank Oct 2018

Inference Of Genetic Regulatory Networks With Recurrent Neural Network Models Using Particle Swarm Optimization, Rui Xu, Donald C. Wunsch, Ronald L. Frank

Donald C. Wunsch

Genetic regulatory network inference is critically important for revealing fundamental cellular processes, investigating gene functions, and understanding their relations. The availability of time series gene expression data makes it possible to investigate the gene activities of whole genomes, rather than those of only a pair of genes or among several genes. However, current computational methods do not sufficiently consider the temporal behavior of this type of data and lack the capability to capture the complex nonlinear system dynamics. We propose a recurrent neural network (RNN) and particle swarm optimization (PSO) approach to infer genetic regulatory networks from time series gene ...


A General Recurrent Neural Network Approach To Model Genetic Regulatory Networks, Xiao Hu, Ann M. Maglia, Donald C. Wunsch Oct 2018

A General Recurrent Neural Network Approach To Model Genetic Regulatory Networks, Xiao Hu, Ann M. Maglia, Donald C. Wunsch

Donald C. Wunsch

There is an urgent need for tools to unravel the complex interactions and functionalities of genes. As such, there has been much interest in reverse-engineering genetic regulatory networks from time series gene expression data. We use an artificial neural network to model the dynamics of complicated gene networks and to learn their parameters. The positive and negative regulations of genes are defined by a weight matrix, and different genes are allowed to have different decaying time constants. We demonstrate the effectiveness of the method by recreating the SOS DNA Repair network of Escherichia coli bacterium, previously discovered through experimental data.


Spatial Structuring Of Cellulase Gene Abundance And Activity In Soil, Jinlyung Choi, Elizabeth Bach, Jaejin Lee, Jared Flater, Shane Dooley, Adina Howe, Kirsten S. Hofmockel Oct 2018

Spatial Structuring Of Cellulase Gene Abundance And Activity In Soil, Jinlyung Choi, Elizabeth Bach, Jaejin Lee, Jared Flater, Shane Dooley, Adina Howe, Kirsten S. Hofmockel

Agricultural and Biosystems Engineering Publications

Microbial mechanisms controlling cellulose degradation in soil habitats remains a critical knowledge gap in understanding and modeling terrestrial carbon-cycling. We investigated land management and soil micro-habitat influences on soil bacterial communities and distribution of cellulose-degrading enzyme genes in three bioenergy cropping systems (corn, prairie, and fertilized prairie). Within the soil, aggregates have been examined as potential micro- habitats with specific characteristics influencing resource partitioning and regulation, thus we also investigated genes associated with cellulose degradation within soil aggregate fractions from the fertilized prairie system. Soil bacterial communities and carbon-cycling gene presence varied across land management and soil microhabitats. Examination of ...


Vaccination Strategies And Herd Immunity Thresholds In Small World Models, Emily Mcclung, Sam Rivas, Emma Soriano, Caelan Thomas, Hannah Highlander Oct 2018

Vaccination Strategies And Herd Immunity Thresholds In Small World Models, Emily Mcclung, Sam Rivas, Emma Soriano, Caelan Thomas, Hannah Highlander

Mathematics Undergraduate Publications, Presentations and Projects

Infectious diseases pose a serious threat to humans, plants, and animals. Though vaccines can help control outbreaks of infectious diseases, there is typically not enough vaccine available for the entire population. In this case, certain vaccination strategies can be employed to maximize the benefits for the entire population. Using results from graph theory and the simulation tool lONTW (Infections On NeTWorks), we investigated various vaccination strategies on certain types of so-called contact networks that model the patterns of interactions within a population. In particular, we focused on a certain class of contact networks known as small world models, where individuals ...


Consistent And Reproducible Cultures Of Large-Scale 3d Mammary Epithelial Structures Using An Accessible Bioprinting Platform, John A. Reid, Peter M. Mollica, Robert D. Bruno, Patrick C. Sachs Oct 2018

Consistent And Reproducible Cultures Of Large-Scale 3d Mammary Epithelial Structures Using An Accessible Bioprinting Platform, John A. Reid, Peter M. Mollica, Robert D. Bruno, Patrick C. Sachs

Medical Diagnostics & Translational Sciences Faculty Publications

Background: Standard three-dimensional (3D) in vitro culture techniques, such as those used for mammary epithelial cells, rely on random distribution of cells within hydrogels. Although these systems offer advantages over traditional 2D models, limitations persist owing to the lack of control over cellular placement within the hydrogel. This results in experimental inconsistencies and random organoid morphology. Robust, high-throughput experimentation requires greater standardization of 3D epithelial culture techniques.

Methods: Here, we detail the use of a 3D bioprinting platform as an investigative tool to control the 3D formation of organoids through the "self-assembly" of human mammary epithelial cells. Experimental bioprinting procedures ...