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Articles 31 - 37 of 37
Full-Text Articles in Life Sciences
Effects Of Berberine, Chelerythrine, And Sanguinarine On Proliferation In Four Human Immortalized Cell Lines, David S. Senchina, Nisarg B. Shah, Marc G. Busch
Effects Of Berberine, Chelerythrine, And Sanguinarine On Proliferation In Four Human Immortalized Cell Lines, David S. Senchina, Nisarg B. Shah, Marc G. Busch
Journal of the Iowa Academy of Science: JIAS
Bloodroot (Sanguinaria canadensis L., Papaveraceae) is a plant rich in benzophenanchridine (isoquinoline) alkaloids such as sanguinarine and chelerychrine. Both isolated alkaloids and whole-tissue rhizome extracts have demonstrated in vitro anticarcinogenic (antiproliferacive) activity in limited immortalized cell culture models, but the relative contribution of various alkaloid constituents to whole-tissue extract activity, and whether or not various alkaloids may act synergistically, has not been investigated. We challenged four immortalized cell lines (Jurkat, K562, Ramos, U937) with various doses of chelerythrine, sanguinarine, and berberine (a structurally and functionally similar alkaloid absent from bloodroot), alone and in all possible combinations, and measured proliferation …
Table Of Contents (Back Cover)
Table Of Contents (Back Cover)
Journal of the Iowa Academy of Science: JIAS
No abstract provided.
Evidence From Detrital Zircon Ages For Middle Pennsylvanian Uplift And Drainage In The Source Area Of The Chariton Conglomerate And Marmaton Group Sandstones, Southern Iowa And Northern Missouri, Scott Mcfadden, Steven H. Emerman, Jane Pedrick Dawson, Kevin A. Rey, Tracy Kemp Anderson
Evidence From Detrital Zircon Ages For Middle Pennsylvanian Uplift And Drainage In The Source Area Of The Chariton Conglomerate And Marmaton Group Sandstones, Southern Iowa And Northern Missouri, Scott Mcfadden, Steven H. Emerman, Jane Pedrick Dawson, Kevin A. Rey, Tracy Kemp Anderson
Journal of the Iowa Academy of Science: JIAS
The Chariton Conglomerate is a quartz/limestone conglomerate of Middle Pennsylvanian age sparsely exposed in southern Iowa and northern Missouri. In Iowa it is characterized by quartz granules and rounded crinoid columnals. The objective of this study was to use detrital zircon ages to determine the provenance of the Chariton Conglomerate and possibly associated Marmaton Group sandstone beds. Detrital zircon ages were obtained for five conglomerate and two sandstone beds of the Chariton Conglomerate in Iowa, three conglomerate beds of the Chariton Conglomerate in Missouri, and two sandstone beds of the Marmaton Group in Iowa. According to the Kolmogorov-Smirnoff Test, the …
Harlan's Ground Sloth (Paramylodon Harlant) (Xenarthra: Mylodontidae) From The Late Pleistocene (Rancholabrean) Of Iowa, H. Gregory Mcdonald
Harlan's Ground Sloth (Paramylodon Harlant) (Xenarthra: Mylodontidae) From The Late Pleistocene (Rancholabrean) Of Iowa, H. Gregory Mcdonald
Journal of the Iowa Academy of Science: JIAS
Harlan's ground sloth, Paramylodon harlani, is documented for the first time from Iowa. The record is based on a fifth metacarpal recovered from a gravel bar within West Tarkio Creek, Page County. While the specimen was not found in situ, and could not be radiocarbon dated, the local geology suggests that it was probably derived from sediments that post-date Peorian loess deposition and is late Wisconsinan in age. This specimen extends the range of Paramylodon 350 km ro the northeast of the closest previously known locality. Its size is slightly larger than average for other late Pleisrocene (Rancholabrean) …
The Journal Of Undergraduate Research: Volume 10
The Journal Of Undergraduate Research: Volume 10
The Journal of Undergraduate Research
This is the complete issue of the South Dakota State University Journal of Undergraduate Research, Volume 10.