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Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
Cell Type Difference In Influenza A Viral Mrna Nuclear Export, Sean William Larsen
Cell Type Difference In Influenza A Viral Mrna Nuclear Export, Sean William Larsen
Theses Digitization Project
The focus of this thesis research was to clarify the role of host Nxf1 in influenza viral mRNA nuclear export. This study aims to define the nuclear mRNA export pathways of influenza viral mRNA. If viral mRNAs are discovered to utilize neither known mRNA nuclear export pathway this would indicate the mRNA exports via undefined mRNA nuclear export pathway. This might be an atypical pathway not utilized by many host mRNAs and thus might reveal novel antiviral target. 293T (Human embryonic kidney cells) and A549 (Human lung epithelial) cells were purchased from ATCC American Tissue Culture Collection.
Using The Polymerase Chain Reaction To Determine The Prevalence Of Lyme Disease Bacteria, Borrelia Burgdorferi, In Ixodes Pacificus Ticks From San Bernardino County In Southern California, Richard Allen
Theses Digitization Project
The purpose of this study was to determine the prevalence of Lyme Disease (LD) bacteria in adult Ixodes pacificus ticks collected from the mountains of San Bernardino County in Southern California. Seven hundred fifty four I. pacificus adults were collected from the Pacific Crest Trail and adjacent areas. The Polymerase Chain Reaction (PCR) was used to screen ticks for Borrelia burgdorferi infection by targeting two different DNA loci. Oligonucleotide primers targeting both the ospA and fla genes were used in the assay. Ticks were processed in pools of three, and genomic DNA from the ticks was extracted with a commercial …