Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
Ros And Sfk Signaling Is Required For Development Of Hematopoietic Stem Cells In Zebrafish, Bradley Williams, Erich Damm
Ros And Sfk Signaling Is Required For Development Of Hematopoietic Stem Cells In Zebrafish, Bradley Williams, Erich Damm
Undergraduate Research Posters
ROS and SFK signaling is required for development of hematopoietic stem cells in zebrafish
Bradley Williams and Erich Damm
Background
Hematopoiesis is the process in which the myriad of mature blood cell types, including erythrocytes and leukocytes, develop from hematopoietic stem cells (HSCs) throughout the life of an organism. In vertebrates, HSCs originate from endothelial cells lining the floor of the dorsal aorta. This process is referred to as the endothelial to hematopoietic transition and is likely controlled in part by molecular signals from neighboring cells. Investigation into the molecular signaling mechanisms controlling the development of HSCs is critical to …