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Full-Text Articles in Life Sciences

Ros And Sfk Signaling Is Required For Development Of Hematopoietic Stem Cells In Zebrafish, Bradley Williams, Erich Damm Jan 2023

Ros And Sfk Signaling Is Required For Development Of Hematopoietic Stem Cells In Zebrafish, Bradley Williams, Erich Damm

Undergraduate Research Posters

ROS and SFK signaling is required for development of hematopoietic stem cells in zebrafish

Bradley Williams and Erich Damm

Background

Hematopoiesis is the process in which the myriad of mature blood cell types, including erythrocytes and leukocytes, develop from hematopoietic stem cells (HSCs) throughout the life of an organism. In vertebrates, HSCs originate from endothelial cells lining the floor of the dorsal aorta. This process is referred to as the endothelial to hematopoietic transition and is likely controlled in part by molecular signals from neighboring cells. Investigation into the molecular signaling mechanisms controlling the development of HSCs is critical to …


The Collaboration Between Art And Botany, Hee So, Sierra Beecher Jan 2023

The Collaboration Between Art And Botany, Hee So, Sierra Beecher

Undergraduate Research Posters

Using past research from my work study with Dr. Beecher where a team of students focused on quantitative and diagnostic anatomies of salt marsh and beach grasses on the Atlantic coasts, I used the research collected and created vector-based diagrams that were easily readable for Biology students at VCU. These illustrations were used in a manuscript we have been preparing, which has been accepted by the “Castanea” scientific journal. During the research fellowship, I was able to design a poster that portrayed the benefits of collaboration between art and botany, and Dr. Beecher presented the poster at the ASPB conference …


Comparing The Microbiomes Of Dental Plaques In 19th Century Ancestral Remains, Ananya Udyaver Jan 2023

Comparing The Microbiomes Of Dental Plaques In 19th Century Ancestral Remains, Ananya Udyaver

Undergraduate Research Posters

During the construction of VCU’s Hermes A. Kontos Medical Sciences Building in April 1994, nineteenth century ancestral remains were found in an abandoned well on the Medical College of Virginia (MCV) campus. This well, now known as the East Marshall Street Well (EMSW), is thought to have been used as a disposal location for cadaver dissection for surgical and other medical waste in the past. VCU is now seeking to use DNA sequencing technology to match and assemble bones from each individual for a proper burial, uncover the cultural and historical context in which these people lived, and bring a …


Proposing An Rna Interference (Rnai)-Based Treatment For Human Immunodeficiency Virus (Hiv) By Analyzing The Post-Transcriptional Gene Targeting Of Sars-Cov-2, Hepatitis C Virus, And A549 Lung Cancer Cells, Arjun Jagdeesh Jan 2023

Proposing An Rna Interference (Rnai)-Based Treatment For Human Immunodeficiency Virus (Hiv) By Analyzing The Post-Transcriptional Gene Targeting Of Sars-Cov-2, Hepatitis C Virus, And A549 Lung Cancer Cells, Arjun Jagdeesh

Undergraduate Research Posters

Human Immunodeficiency Virus (HIV) is a retrovirus that infects CD4+ T cell lymphocytes in humans, leading to the development of Acquired Immunodeficiency Syndrome (AIDS) if left untreated. While current treatment methods, including antiretroviral combination treatments, effectively limit HIV replication, HIV can evade these treatments due to its high mutation rate. Long-term antiretroviral treatment can also be toxic to patients, meaning patients would benefit from a new mechanism of HIV treatment. RNA interference (RNAi) is an antiviral pathway found in mammals, plants, and insects that involves a small-interfering RNA that is incorporated into a protein complex called the RNA-induced Silencing Complex …