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Full-Text Articles in Life Sciences
From “Glycosyltransferase” To “Congenital Muscular Dystrophy”: Integrating Knowledge From Ncbi Entrez Gene And The Gene Ontology, Satya S. Sahoo, Kelly Zeng, Olivier Bodenreider, Amit P. Sheth
From “Glycosyltransferase” To “Congenital Muscular Dystrophy”: Integrating Knowledge From Ncbi Entrez Gene And The Gene Ontology, Satya S. Sahoo, Kelly Zeng, Olivier Bodenreider, Amit P. Sheth
Kno.e.sis Publications
Entrez Gene (EG), Online Mendelian Inheritance in Man (OMIM) and the Gene Ontology (GO) are three complementary knowledge resources that can be used to correlate genomic data with disease information. However, bridging between genotype and phenotype through these resources currently requires manual effort or the development of customized software. In this paper, we argue that integrating EG and GO provides a robust and flexible solution to this problem. We demonstrate how the Resource Description Framework (RDF) developed for the Semantic Web can be used to represent and integrate these resources and enable seamless access to them as a unified resource. …
What, Where And When: Supporting Semantic, Spatial And Temporal Queries In A Dbms, Matthew Perry, Amit P. Sheth, Farshad Hakimpour, Prateek Jain
What, Where And When: Supporting Semantic, Spatial And Temporal Queries In A Dbms, Matthew Perry, Amit P. Sheth, Farshad Hakimpour, Prateek Jain
Kno.e.sis Publications
Spatial and temporal data are critical components in many applications. This is especially true in analytical domains such as national security and criminal investigation. The outcome of the analytical process in these applications often hinges on uncovering and analyzing complex relationships between disparate people, places and events. Fundamentally new query operators based on the graph structure of Semantic Web data models, such as semantic associations, are proving useful in these applications. However, these analysis mechanisms are primarily intended for thematic relationships. We describe a framework built around the RDF metadata model for analysis of thematic, spatial and temporal relationships between …