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Full-Text Articles in Life Sciences

Synthesis, Molecular Characteristics, And Antibacterial Assessment Of Marine Hydroid Aqueous Extract-Based Silver Bio-Nanoparticles, Fredryk Mandey, Aulia Rhamdani Arfan, Rugaiyah Andi Arfah Mar 2024

Synthesis, Molecular Characteristics, And Antibacterial Assessment Of Marine Hydroid Aqueous Extract-Based Silver Bio-Nanoparticles, Fredryk Mandey, Aulia Rhamdani Arfan, Rugaiyah Andi Arfah

Makara Journal of Science

This investigation aims to synthesize, analyze the molecularity, and test the ability of bacterial inhibition capability of silver nanoparticles that have been synthesized by simply mixing silver nitrate and aqueous extracts of marine natural products with and without the addition of amylum as a stabilizing agent. This research, with and without the addition of amylum as a stabilizing agent, obtained 39.0 and 55.2 mg of solids of round-shaped morphology silver nanoparticles with diameters of 87.9 and 103.0 nm., respectively. In addition, the antibacterial testing assay against Staphylococcus aureus and Escherichia coli showed some considerably good results. S. aureus with the …


In Silico Analysis Of C-Type Lectins As Co-Infection Receptors Of Dengue And Chikungunya Viruses In Aedes Aegypti, Munawir Sazali, R. C. Hidayat Soesilohadi, Nastiti Wijayanti, Tri Wibawa, Arif Nur Muhammad Ansori Mar 2024

In Silico Analysis Of C-Type Lectins As Co-Infection Receptors Of Dengue And Chikungunya Viruses In Aedes Aegypti, Munawir Sazali, R. C. Hidayat Soesilohadi, Nastiti Wijayanti, Tri Wibawa, Arif Nur Muhammad Ansori

Makara Journal of Science

Aedes aegypti is a primer vector of dengue virus (DENV) and chikungunya virus (CHIKV). The susceptibility of mosquitoes to DENV and CHIKV depends on their recognition receptor of pathogens. C-type lectins (CTLs) are an important mediator of virus infection in A. aegypti. This study aims to identify potential receptors and determine the binding affinity between ligand–receptor interaction, CTLs and virus envelopes (DENV-1, 2, 3, and 4 and CHIKV) interaction based on in silico analysis. Sample sequences were obtained from GenBank (NCBI), and 10 CTLs were acquired from VectorBase. Homology modeling based on a minimum standard of 20% was processed …


An Inkjet-Printed Graphene Oxide–Poly(3,4-Ethylenedioxythiophene) Poly(Styrene Sulfonate) Electrode For Nitrite Detection In Water, Budi Riza Putra, Weni Anindya, Mohamad Rafi, Ika Kartika, Yudi Nugraha Thaha, Aga Ridhova, Wulan Tri Wahyuni Dec 2023

An Inkjet-Printed Graphene Oxide–Poly(3,4-Ethylenedioxythiophene) Poly(Styrene Sulfonate) Electrode For Nitrite Detection In Water, Budi Riza Putra, Weni Anindya, Mohamad Rafi, Ika Kartika, Yudi Nugraha Thaha, Aga Ridhova, Wulan Tri Wahyuni

Makara Journal of Science

In this study, a screen-printed electrode (SPE) for nitrite (NO2) sensing was fabricated through an inkjet printing technique using a commercial printer machine and preparing an ink composite solution containing graphene oxide (GO) and poly(3,4 ethylenedioxythiophene) poly(styrene sulfonate) (PEDOT:PSS) as conductive materials. The optimum ink materials for SPE fabrication comprised GO and PEDOT:PSS with binders that resemble the viscosity of commercial ink. The surface topography of the fabricated SPE, which was characterized using scanning electron microscopy and atomic force microscopy, showed a smoother surface compared to the commercial screen-printed carbon electrode, with conductive ink materials deposited primarily …


Synthesis, Characterization, Antibacterial Activity, And Potential Water Filter Application Of Copper Oxide/Zeolite Composite, Elfa Aida Kamila, Zaenal Abidin, Irma Isnafia Arief, Trivadila Trivadila Sep 2023

Synthesis, Characterization, Antibacterial Activity, And Potential Water Filter Application Of Copper Oxide/Zeolite Composite, Elfa Aida Kamila, Zaenal Abidin, Irma Isnafia Arief, Trivadila Trivadila

Makara Journal of Science

Detection of E. coli bacteria in water samples can indicate the presence of other bacterial contamination in feces. Bacterial contamination can be treated with antibiotics, but excessive use of antibiotics leads to the emergence of multiresistant bacteria. Therefore, alternative antibacterial agents must be explored. Copper ion/zeolite composite has been widely studied as an antibacterial agent. However, the released copper ions accumulate in water and are toxic to humans; this can be prevented by converting copper ions into copper oxides (CuO and Cu2O). In this study, copper oxide/zeolite composite is synthesized and characterized using the heating method, followed by …


Physicochemical Changes And Role Of Analytical Chemistry In Black Garlic (Allium Sativum L.) Processing, Surjani Wonorahardjo, Dian Puspita Sari, Arini Salsabila, Estiyawati Estiyawati, Dewi Yuliani, Anugrah Ricky Wijaya, Suharti Suharti, Irma Kartika Kusumaningrum, Chariztya Anggita Maharani, Thjiong Angelina Noviyanti Jun 2023

Physicochemical Changes And Role Of Analytical Chemistry In Black Garlic (Allium Sativum L.) Processing, Surjani Wonorahardjo, Dian Puspita Sari, Arini Salsabila, Estiyawati Estiyawati, Dewi Yuliani, Anugrah Ricky Wijaya, Suharti Suharti, Irma Kartika Kusumaningrum, Chariztya Anggita Maharani, Thjiong Angelina Noviyanti

Makara Journal of Science

Black garlic is a traditional spice having potential of herbal medicine; however, continuous heating darkens its color and changes its taste due to chemical processes and new equilibrium in the system. In this study, fresh garlic was processed into black garlic at 60 °C for 24 days. Changes in physical and chemical parameters, such as browning and protein content, reducing sugar content, and antioxidative components were recorded. Protein content was measured by Kjeldahl method, brown color development was analyzed using a color reader, reducing sugar was examined using a dinitro salicylic DNS reagent, and antioxidative activities were studied with a …


Estimation Of The Bubble Point Pressure Of Multicomponent Reservoir Hydrocarbon Fluids, Benjamin Sunday Usen, Chidi Obi Sep 2022

Estimation Of The Bubble Point Pressure Of Multicomponent Reservoir Hydrocarbon Fluids, Benjamin Sunday Usen, Chidi Obi

Makara Journal of Science

This study developed a novel C-sharp (C#) programming language for the estimation of bubble point pressure (BPP) of various hydrocarbon mixtures at equilibrium state. The methodology was based on vapor–liquid equilibrium calculation using Peng Robinson equation of state implementation, thermodynamic equilibrium calculation and Newton-Raphson’s method for the successive substitution of the unknown variables. The equal fugacity constraint can be satisfied by obtaining the equilibrium which serves as a criterion for two or more phases to exist at equilibrium. The problem was resolved by searching for a pressure that will satisfy the two constraints. Complex calculation was performed by successively substituting …


Co-Microencapsulation Of Ruellia Tuberosa L. And Cosmos Caudatus K. Extracts For Pharmaceutical Applications, Choirin Annisa, Sasangka Prasetyawan, Anna Safitri Jun 2022

Co-Microencapsulation Of Ruellia Tuberosa L. And Cosmos Caudatus K. Extracts For Pharmaceutical Applications, Choirin Annisa, Sasangka Prasetyawan, Anna Safitri

Makara Journal of Science

This study aims to co-microencapsulate the Ruellia tuberosa L. and Cosmos caudatus K. extracts, with chitosan–sodium tripolyphosphate (Na-TPP) as coating material. α-Amylase inhibition and antioxidant assays were conducted to determine the potential of microcapsules used as antidiabetic agents. The microcapsules were manufactured under the influences of pH, Na-TPP concentration, and stirring time. The optimum microencapsulation conditions were selected based on the highest encapsulation efficiency. The optimum microencapsulation conditions were a pH of 4, Na-TPP concentration of 0.15% (w/v), and stirring time of 60 min. The microcapsules exhibited an IC50 (inhibitory concentration) value of 223.64 ± 0.81 µg/mL and an …


Application Of Gellan Gum Biopolymer In Biomedical Applications: A Review, Norsyakirah Izzati Hishamuddin, Mohd Hasmizam Razali, Khairul Anuar Mat Amin Mar 2022

Application Of Gellan Gum Biopolymer In Biomedical Applications: A Review, Norsyakirah Izzati Hishamuddin, Mohd Hasmizam Razali, Khairul Anuar Mat Amin

Makara Journal of Science

Gellan gum (GG) has gained considerable attention in the food, chemical, and pharmaceutical industries due to its functional characteristics. It has versatile properties, such as water solubility, easy bio-fabrication, good film/hydrogel-formation, biodegradability, and biocompatibility. These properties render GG a promising material in biomedical applications, specifically in the development of wound dressing materials. In this review, the use of GG biopolymer as a wound dressing material was discussed. Various fillers, such as titanium dioxides, clay, drug, and honey, have been incorporated in GG to produce film, hydrogel, or scaffold materials. The effects of filler on the mechanical performance, physical properties, antibacterial …


Effects Of Different Extraction Solvents On The Extractive Removal And Properties Of Oil Palm Empty-Fruit Bunch Cellulosic Nanofibers, Achmad Solikhin, Yusuf Sudo Hadi, Muh Yusram Massijaya, Siti Nikmatin Sep 2021

Effects Of Different Extraction Solvents On The Extractive Removal And Properties Of Oil Palm Empty-Fruit Bunch Cellulosic Nanofibers, Achmad Solikhin, Yusuf Sudo Hadi, Muh Yusram Massijaya, Siti Nikmatin

Makara Journal of Science

In this study, the effect of different extraction solvents on the isolation and properties of cellulosic nanofibers (CNFs) were investigated. The unextracted and different solvent-extracted CNFs formed horn-like features and irregularly aggregated nanofibers after oven drying. Scanning electron microscopy at 10000× magnification revealed the smooth external surfaces of all extracted CNFs; this finding is attributed to the limited deposition of amorphous lignocellulosic components on the fibers. All resultant CNF solutions revealed aggregation, with a particle size distribution and zeta average of 21.39–513.00 nm and 162.26–342.13 nm, respectively. Extraction with different solvents and chemical treatment yielded CNF solutions with good transparency. …