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Cell and Developmental Biology

1999

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Articles 31 - 35 of 35

Full-Text Articles in Life Sciences

Plasmd Bearing A Cdna Copy Of The Genome Of Bovine Viral Diarrhea Virus, Chimeric Derivatives Thereof, And Method Of Producing An Infectious Bovine Wral Darrheavirus Using Sad Plasmid, Ruben O. Donis, Ventzislav B. Vassilev Jan 1999

Plasmd Bearing A Cdna Copy Of The Genome Of Bovine Viral Diarrhea Virus, Chimeric Derivatives Thereof, And Method Of Producing An Infectious Bovine Wral Darrheavirus Using Sad Plasmid, Ruben O. Donis, Ventzislav B. Vassilev

School of Veterinary and Biomedical Sciences: Faculty Publications

A plasmid bearing a cDNA copy of the genome of bovine viral diarrhea virus (BVDV), chimeric derivatives of the plasmid and a method of producing an infectious bovine viral diarrhea virus using the plasmid are disclosed. The invention relates to a plasmid DNA molecule that replicates easily in E. coli and contains a sufficient portion of the genome of BVDV, cloned as cDNA, to be a suitable template to produce RNA in vitro which, upon transfection into bovine cells, gives rise to infectious BVDV. The BVDV created by the process of the invention can be engineered for use as a …


Relationships Between Experience, Credentials, Moral Development, Conceptual Level, And Self-Efficacy Of School Counselors, Susan Emilie Halverson Jan 1999

Relationships Between Experience, Credentials, Moral Development, Conceptual Level, And Self-Efficacy Of School Counselors, Susan Emilie Halverson

Dissertations, Theses, and Masters Projects

No abstract provided.


Phylogenetic Implications Of Sporangial Ultrastructure In The Subfamily Lithophylloideae (Corallinales, Rhodophyta), Mark T. Bedell Jan 1999

Phylogenetic Implications Of Sporangial Ultrastructure In The Subfamily Lithophylloideae (Corallinales, Rhodophyta), Mark T. Bedell

Dissertations, Theses, and Masters Projects

No abstract provided.


Inhibition Of Cpla2-Mediated Arachidonic Acid Release By Cyclic Amp Defines A Negative Feedback Loop For P2y-Receptor Activation In Mdck-D1 Cells, Mingzhao Xing, Steven Post, Rennolds S. Ostrom, Michael Samardzija, Paul A. Insel Jan 1999

Inhibition Of Cpla2-Mediated Arachidonic Acid Release By Cyclic Amp Defines A Negative Feedback Loop For P2y-Receptor Activation In Mdck-D1 Cells, Mingzhao Xing, Steven Post, Rennolds S. Ostrom, Michael Samardzija, Paul A. Insel

Pharmacy Faculty Articles and Research

In Madin-Darby canine kidney D1cells extracellular nucleotides activate P2Y receptors that couple to several signal transduction pathways, including stimulation of multiple phospholipases and adenylyl cyclase. For one class of P2Y receptors, P2Y2 receptors, this stimulation of adenylyl cyclase and increase in cAMP occurs via the conversion of phospholipase A2 (PLA2)-generated arachidonic acid (AA) to prostaglandins (e.g. PGE2). These prostaglandins then stimulate adenylyl cyclase activity, presumably via activation of prostanoid receptors. In the current study we show that agents that increase cellular cAMP levels (including PGE2, forskolin, and the β-adrenergic agonist isoproterenol) can inhibit P2Y receptor-promoted AA release. The protein kinase …


Characterization Of A Mutant T Cell Hybridoma Line With Defects In Tcr-Mediated Apoptotic Pathway, Sallie Smith Schneider, G. Morgan, S.W. Smith, L. Pak, A. Marshak-Rothstein, R. Fissore, B.A. Osborne Dec 1998

Characterization Of A Mutant T Cell Hybridoma Line With Defects In Tcr-Mediated Apoptotic Pathway, Sallie Smith Schneider, G. Morgan, S.W. Smith, L. Pak, A. Marshak-Rothstein, R. Fissore, B.A. Osborne

Sallie W Smith Schneider

No abstract provided.