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Full-Text Articles in Life Sciences
Fibrinogen-Conjugated Gold-Coated Magnetite Nanoparticles For Targeting Activated Platelets In A Whole Blood System, Cammy Nu Truong
Fibrinogen-Conjugated Gold-Coated Magnetite Nanoparticles For Targeting Activated Platelets In A Whole Blood System, Cammy Nu Truong
Theses and Dissertations
Activated platelets are a key component of the arterial thrombi responsible for heart attack and stroke. Tissue plasminogen activator (tPA) is currently the only FDA-approved drug for ischemic stroke. It works by dissolving fibrin, thus breaking down the clot and restoring blood flow to the brain. However, it must be administered within 4.5 hours of the onset of stroke. This leaves a significant number of patients who are ineligible for intervention and who have poor clinical outcomes. Additionally, tPA is not injury site-specific; consequently, the side effects range from mild to severe. We are investigating targeting activated platelets in occlusive …
Characterization Of Extracellular Vesicles Isolated From Human Milk Using A Precipitation-Based Method, Diana C. Bickmore, John Miklavcic
Characterization Of Extracellular Vesicles Isolated From Human Milk Using A Precipitation-Based Method, Diana C. Bickmore, John Miklavcic
Food Science Faculty Articles and Research
Extracellular vesicles (EV) function in intercellular communication, and those in human milk may confer immunologic benefits to infants. Methods of EV isolation such as ultracentrifugation (UC) may not be feasible for the study of EVs in human milk due to the need for large sample volume. A technique to isolate EVs from a small volume of human milk using a precipitation reagent is described herein. Electron microscopy, nanoparticle tracking analysis, and semi-quantitative antibody array were conducted to confirm isolation of human milk EVs. Count, size, protein content, and fatty acid quantification of EVs were determined. This isolation technique yielded 8.9 …
Application Of 3d Printing Technology In Porous Anode Fabrication For Enhanced Power Output Of Microbial Fuel Cells, Bin Bian
Electronic Thesis and Dissertation Repository
Microbial fuel cells (MFCs) are widely researched for application in wastewater treatment. However, the current anodes used in MFCs often suffer from high fabrication cost and uncontrollable pore sizes. In this thesis, three-dimensional printing technique was utilized to fabricate anodes with different micro pore sizes for MFCs. Copper coating and carbonization were applied to the printed polymer anodes to increase the conductivity and specific surface area. Voltages of MFCs with various anodes were measured as well as other electrochemical tests such as linear sweep voltammetry and electrochemical impedance spectroscopy. 3D copper porous anode produced higher maximum voltages and power densities …