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Mesua Ferrea L. (Calophyllaceae) Exerts Therapeutic Effects In Allergic Asthma Bymodulating Cytokines Production In Asthmatic Rats, Poonam Arora, Shahid Hamid Ansari, Lalit Mohan Nainwal

Turkish Journal of Botany

In the present study, ethanolic extract of Mesua ferrea L. stamens was investigated for its potential to reverse some features of bronchial asthma in ovalbumin-induced murine model of asthma. Mesua ferrea commonly called nagakeshar (Family, Calophyllaceae) is a well-known antiallergic drug in the Asian folk system of medicines. In the present work, pharmacological studies are done to provide scientific evidence for therapeutic potential of plants in allergic asthma. Asthma was induced in experimental rats with allergen suspension of ovalbumin and aluminium hydroxide followed by treatment with dexamethasone (2.5 mg/Kg, p.o) or M. ferrea stamen extract (3.75 and 15 mg/Kg, b.w., …