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Full-Text Articles in Life Sciences

The Evolution Of Zinjanthropus Boisei, Paul J. Constantino, Bernard A. Wood Mar 2007

The Evolution Of Zinjanthropus Boisei, Paul J. Constantino, Bernard A. Wood

Biological Sciences Faculty Research

Many people assume that OH 5, the type specimen of Paranthropus boisei, collected in 1959, was the first evidence of that taxon to be found, but OH 3, recovered in 1955, predated the discovery of OH 5 by four years. Thus, Paranthropus boisei recently celebrated the equivalent of its fiftieth birthday. This review marks that milestone by examining the way our understanding of this taxon has changed during its fifty, or so, year history.


Chronic Acetaminophen Treatment Influences Indices Of Reactive Oxygen Species Accumulation In The Aging Fisher 344 X Brown Norway Rat Aorta, Sarath Meduru Jan 2007

Chronic Acetaminophen Treatment Influences Indices Of Reactive Oxygen Species Accumulation In The Aging Fisher 344 X Brown Norway Rat Aorta, Sarath Meduru

Theses, Dissertations and Capstones

We have previously reported that aging in the Fisher 344 X Brown Norway (FBN) rat aorta is characterized by increased levels of ROS and alterations in cell signaling. Acetaminophen was found to scavenge free radicals in recent ischemia-reperfusion studies. Here we examined if chronic treatment with a therapeutic dose of acetaminophen attenuates age-associated increase in aortic ROS accumulation and signaling. FBN rats (27 month old; n=8) were subjected to 6 months of treatment with a therapeutic dose of acetaminophen (30mg/kg/day), with age-matched untreated FBN rats as controls. Protein oxidation levels were altered in control and treated aortae compared to aortae …