Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- The Texas Medical Center Library (9)
- University of Texas at El Paso (8)
- City University of New York (CUNY) (6)
- Georgia Southern University (5)
- University of Texas Rio Grande Valley (5)
-
- Washington University in St. Louis (5)
- University of South Carolina (4)
- University of South Florida (4)
- University of Nebraska Medical Center (3)
- Utah State University (3)
- Andrews University (2)
- Butler University (2)
- Missouri State University (2)
- Seton Hall University (2)
- Texas Southern University (2)
- The University of San Francisco (2)
- University at Albany, State University of New York (2)
- University of Arkansas, Fayetteville (2)
- Virginia Commonwealth University (2)
- Wayne State University (2)
- American University in Cairo (1)
- Brigham Young University (1)
- Claremont Colleges (1)
- Clemson University (1)
- Cleveland State University (1)
- Coastal Carolina University (1)
- Colby College (1)
- DePaul University (1)
- Jacksonville State University (1)
- John Carroll University (1)
- Publication Year
- Publication
-
- Theses and Dissertations (12)
- Dissertations & Theses (Open Access) (9)
- Open Access Theses & Dissertations (8)
- Arts & Sciences Electronic Theses and Dissertations (5)
- Dissertations, Theses, and Capstone Projects (5)
-
- Honors College Theses (5)
- Honors Theses (4)
- USF Tampa Graduate Theses and Dissertations (4)
- Theses & Dissertations (3)
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (2)
- Biological Sciences Undergraduate Honors Theses (2)
- Doctoral Dissertations (2)
- Electronic Theses and Dissertations (2)
- Legacy Theses & Dissertations (2009 - 2024) (2)
- MSU Graduate Theses (2)
- Master's Theses (2)
- Seton Hall University Dissertations and Theses (ETDs) (2)
- Theses (2)
- Theses (2016-Present) (2)
- Undergraduate Honors Thesis Collection (2)
- All Dissertations (1)
- All NMU Master's Theses (1)
- Biology ETDs (1)
- Biomedical Sciences Theses & Dissertations (1)
- CMC Senior Theses (1)
- College of Arts & Sciences Senior Honors Theses (1)
- College of Science and Health Theses and Dissertations (1)
- Dissertations (1)
- ETD Archive (1)
- Electronic Thesis and Dissertation Repository (1)
Articles 91 - 97 of 97
Full-Text Articles in Life Sciences
Antimicrobial And Anticancer Activity Of Essential Oils From Guatemalan Medicinal Plants, Andrew B. Miller
Antimicrobial And Anticancer Activity Of Essential Oils From Guatemalan Medicinal Plants, Andrew B. Miller
Theses and Dissertations
Guatemalan medicinal plants were collected and screened for the presence of essential oils using steam distillation. Oil was found in 63 species from 24 families and was tested in tube dilution assays for activity against Escherichia coli, Staphylococcus aureus, Streptococcus mutans, Lactobacillus acidophilus and Candida albicans. Several essential oils were highly active with 20 instances of oils inhibiting the microbes at an MIC of 0.31 µl/ml. Oils were also tested against cancerous and established cell lines using a 15% (v/v) agar-media which was developed to improve essential oil solubility. Assays were performed against three cancer lines: …
Characterizing The Role Of Dna Repair Proteins In Telomere Length Regulation And Maintenance: Fanconi Anemia Complementation Group C Protein And 8-Oxoguanine Dna Glycosylase, David Beomjin Rhee
Characterizing The Role Of Dna Repair Proteins In Telomere Length Regulation And Maintenance: Fanconi Anemia Complementation Group C Protein And 8-Oxoguanine Dna Glycosylase, David Beomjin Rhee
Doctoral Dissertations
Telomeres are the chromosome end structures consisting of telomere-associated proteins and short tandem repeat sequences, TTAGGG, in humans and mice. Telomeres prevent chromosome termini from being recognized as broken DNA ends. The structural integrity of DNA including telomeres is constantly threatened by a variety of DNA damaging agents on a daily basis. To counteract the constant threats from DNA damage, organisms have developed a number of DNA repair pathways to ensure that the integrity of genome remains intact. A number of DNA repair proteins localize to telomeres and contribute to telomere maintenance; however, it is still unclear as to what …
Structural Investigation Of Atp-Utilizing Enzymes: Structures Involved In H+ Homeostasis And The Proliferation Of Hormone-Dependent Cancers, Zacariah Louis Hildenbrand
Structural Investigation Of Atp-Utilizing Enzymes: Structures Involved In H+ Homeostasis And The Proliferation Of Hormone-Dependent Cancers, Zacariah Louis Hildenbrand
Open Access Theses & Dissertations
ATP is a multifunctional nucleotide considered to be the "molecular unit of currency" of intracellular energy transfer. ATP is utilized ubiquitously for the transport of chemical energy within the cell in addition to acting as a substrate in the regulation of many metabolic and signaling transduction pathways such as kinase-mediated signaling cascades. Interestingly, the functional mechanisms of many enzymes require the binding of ATP to trigger key structural and conformational changes that ultimately result in enzyme-directed catalysis. Two of the most omnipresent ATPases within the cell include the V-ATPase rotary proton pump and the Hsp90 protein-folding chaperone. Structural and biochemical …
Mechanisms Of Induced Cell Death In Bluetongue Virus Challenged Human Cell Lines, Justin Darrel Hoopes
Mechanisms Of Induced Cell Death In Bluetongue Virus Challenged Human Cell Lines, Justin Darrel Hoopes
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Bluetongue virus (BTV) is a pathogenic member of the Reoviridae family. BTV does not cause disease in humans, but is capable of selectively infecting and killing certain transformed human cell lines. Understanding BTV's oncotrophism may lead to new therapeutics for treating cancer. This study focused on the underlying mechanisms of BTV-induced cell death in carcinoma cell lines. It was our hypothesis that BTV infects human carcinoma transformed cells, produces mRNA and protein, induces a strong inflammatory response, induces mitogen activated protein kinase (MAPK)-based pro-apoptotic signaling, inhibits PKB-based signaling, and eventually kills the cell by inducing apoptosis.
Three carcinoma cell lines …
Inducing A Normal Phenotype In Breast Epithelial Cells Using A Three-Dimensional Basement Membrane Extract Culture System: A Study On The Reversion Of Cancer, Ross H. Booth
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Experimentally, traditional developmental models and transgenic animals consistently underscore the importance of studying cell behavior in the correct tissue context. However, live animal experimentation is inherently complex, and systematic assessment of the effects of individual variables, such as cell shape and matrix compliance on cell behavior, is extremely difficult at best. Two-dimensional monolayer culture of key individual cell types has provided abundant, fundamental information on cell response, but cannot be used to show the normal phenotype of breast epithelial cells. Furthermore, their results often fail to translate into in vivo and clinical studies. It has been previously established that normal …
Myf5 Does Not Induce Apoptosis In Skeletal Myoblasts But Is Regulated By Oncogenic Ras Expression, Alexander Phillip Talarico
Myf5 Does Not Induce Apoptosis In Skeletal Myoblasts But Is Regulated By Oncogenic Ras Expression, Alexander Phillip Talarico
ETD Archive
Skeletal myogenesis is initiated by a family of muscle regulatory factors (MRFs) composed of the transcription factors MyoD, Myf5, MRF4, and myogenin. Of these, MyoD was the first discovered, is the most studied, and plays a well-characterized role in skeletal myoblast determination and differentiation. Our laboratory has also discovered that MyoD plays an important role in the apoptotic process that occurs in a subpopulation of myoblasts induced to differentiate. Expression of oncogenic Ras is known to inhibit myoblast differentiation and to decrease the expression of MyoD mRNA and protein. Our laboratory was the first to report that expression of oncogenic …
The External Morphology Of The First Zoeal Stages Of Cancer Magister (Dana), Cancer Antennarius (Stimpson), And Cancer Anthonyi (Rathbun), Robert Dotson Mir
The External Morphology Of The First Zoeal Stages Of Cancer Magister (Dana), Cancer Antennarius (Stimpson), And Cancer Anthonyi (Rathbun), Robert Dotson Mir
University of the Pacific Theses and Dissertations
The literature dealing with the larva of Pacific Coast brachyuran crabs is slight. The prominent papers, those of Aikawa (1927, 1928, 1929, 1933, 1937), deal with a variety of genera and offer information useful in determin- ing family relationships. A single paper by Hart (1935) also deal with a number of brachyuran larvae found in the Pacific Ocean. None of these papers, however, identifies to species any member of the genus Cancer, although one member, C. magister (Dana) is of considerable economic importance on the pacific coast of North America. In the fall of 1958 an investigation was under taken …