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Articles 1 - 6 of 6
Full-Text Articles in Life Sciences
Polysaccharopeptide Enhances The Anticancer Activity Of Doxorubicin And Etoposide On Human Breast Cancer Cells Zr-75-30, Jennifer Man-Fan Wan, Wai Hung Sit, Jimmy Chun Yu Louie
Polysaccharopeptide Enhances The Anticancer Activity Of Doxorubicin And Etoposide On Human Breast Cancer Cells Zr-75-30, Jennifer Man-Fan Wan, Wai Hung Sit, Jimmy Chun Yu Louie
Jimmy Chun Yu Louie
In search of natural bioactive microbial compounds with adjuvant properties, we have previously showed that the polysaccharopeptide (PSP), isolated from Chinese medicinal mushroom Coriolus versicolor, was able to enhance the cytotoxicity of certain S-phase targeted-drugs on human leukemic HL-60 cells via some cell-cycle and apoptotic-dependent pathways. The present study aimed to investigate whether the synergism of mechanisms of PSP with certain chemotherapeutic drugs also applies to human breast cancer. PSP treatment enhanced the cytotoxicity of doxorubicin (Doxo), etoposide (VP-16) but not cytarabine (Ara-C). Bivariate bromodeoxyuridine (BrdUrd)/DNA flow cytometry analysis estimated a longer DNA synthesis time (Ts) for the PSP treated …
The Danger Of Applying Uniform Clincal Policies Across Populations: The Case Of Breast Cancer In American Indians, Paul Nutting, Ned Calonge, Donald Iverson, Larry Green
The Danger Of Applying Uniform Clincal Policies Across Populations: The Case Of Breast Cancer In American Indians, Paul Nutting, Ned Calonge, Donald Iverson, Larry Green
Don C. Iverson
OBJECTIVES. This study examined the implications of annual screening mammography for cost and mortality in American Indian populations with differing baseline breast cancer rates. METHODS. A decision tree compared annual screening mammography and screening clinical breast examination with referral for diagnostic mammography when appropriate. The decision tree was constructed to examine the effect of different base-line cancer rates, stage at diagnosis, and stage-specific survival. Outcomes included 5-year relative survival, deaths prevented at 5 years, cost per death prevented, and total costs. RESULTS. The findings suggest that the total cost of breast cancer is 3.6 times higher with the screening mammography …
Feasibility Studies Of Low-Fat Diet To Prevent Or Retard Breast Cancer, P Greenwald, C Clifford, R Butrum, Donald Iverson
Feasibility Studies Of Low-Fat Diet To Prevent Or Retard Breast Cancer, P Greenwald, C Clifford, R Butrum, Donald Iverson
Don C. Iverson
No abstract provided.
Australian Women's Awareness Of Breast Cancer Symptoms And Responses To Potential Symptoms, Sandra Jones, Parri Gregory, Caroline Nehill, Lance Barrie, Karen Luxford, A. Nelson, Helen Zorbas, Donald Iverson
Australian Women's Awareness Of Breast Cancer Symptoms And Responses To Potential Symptoms, Sandra Jones, Parri Gregory, Caroline Nehill, Lance Barrie, Karen Luxford, A. Nelson, Helen Zorbas, Donald Iverson
Don C. Iverson
Poor awareness of breast cancer symptoms has been associated with patient delay in seeking help; thus reduced survival, more aggressive treatment, and fewer treatment choices. The aim of this study was to develop a representative picture of Australian women’s knowledge of symptoms, experienced potential symptoms, and behavioral responses. A general population sample of approximately 3,000 women aged 30–69 completed a telephone survey; results were compared to previous surveys conducted in 1996 and 2003. The most commonly cited potential symptom of breast cancer was a lump in the breast, identified by 86% of respondents (an increase from 75% in 2003). Other …
Australian Women's Perceptions Of Breast Cancer Risk Factors And The Risk Of Developing Breast Cancer, Sandra C. Jones, Christopher A. Magee, Lance R. Barrie, Donald C. Iverson, Parri Gregory, Emma L. Hanks, Anne E. Nelson, Caroline L. Nehill, Helen M. Zorbas
Australian Women's Perceptions Of Breast Cancer Risk Factors And The Risk Of Developing Breast Cancer, Sandra C. Jones, Christopher A. Magee, Lance R. Barrie, Donald C. Iverson, Parri Gregory, Emma L. Hanks, Anne E. Nelson, Caroline L. Nehill, Helen M. Zorbas
Don C. Iverson
Background Numerous studies have shown that the majority of women overestimate both their own risk and the populations’ risk of developing breast cancer. A number of factors have been found to correlate with perceived risk. Methods This paper reports on a telephone survey of a nationally representative sample of approximately 3,000 Australian women aged 30 to 69 years, conducted in 2007, and compares the findings with those of a similar survey conducted in 2003. Results There was a clear tendency for respondents to overestimate the proportion of women who will develop breast cancer during their lifetime. Approximately half the respondents …
Relationship Between Breast-Feeding And Adiposity In Infants And Pre-School Children, Bamini Gopinath, Indhu Subramanian, Victoria M. Flood, Louise A. Baur, Natalie Pfund, George Burlutsky, Paul Mitchell
Relationship Between Breast-Feeding And Adiposity In Infants And Pre-School Children, Bamini Gopinath, Indhu Subramanian, Victoria M. Flood, Louise A. Baur, Natalie Pfund, George Burlutsky, Paul Mitchell
Faculty of Health and Behavioural Sciences - Papers (Archive)
Objectives: We aimed to establish associations of duration of breast-feeding with mean BMI and waist circumference, as well as the likelihood of being overweight/ obese, during early childhood. Design: Cross-sectional, population-based study. Height, weight and waist circumference were measured and BMI calculated. Interviewer-administered questionnaire determined whether the child was ever breast-fed and the duration of breast-feeding. Setting: Sydney, Australia. Subjects: Infants and pre-school children (n 2092) aged 1-6 years were examined in the Sydney Paediatric Eye Disease Study during 2007-2009. Results: Of the children aged 1-6 years, 1270 had been breast-fed compared with 822 who were never breast-fed. After multivariable …