Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Examination Of The Effects Breed And Nutrition Have On The Milk Protein Profile Produced By Lactating Dairy Cattle, Rinske Tacoma Jan 2016

Examination Of The Effects Breed And Nutrition Have On The Milk Protein Profile Produced By Lactating Dairy Cattle, Rinske Tacoma

Graduate College Dissertations and Theses

Milk is a highly nutritious natural product and research over the last 10 years has proven that these milk proteins not only provide a rich source of amino acids to the consumer but also contains many bioactive proteins and peptides known to exert biological activity benefitting human health. In this research, proteomic methods were first used to characterize the low abundance proteome within the skim milk fraction produced by Holstein and Jersey dairy cows maintained under the same diet, management and environmental conditions. Milk samples were collected over a seven day period from six Holstein and six Jersey dairy cows. …


Definition Of Bovine Leukocyte Antigen Diversity And Peptide Binding Profiles For Epitope Discovery, Mital Pandya Jan 2016

Definition Of Bovine Leukocyte Antigen Diversity And Peptide Binding Profiles For Epitope Discovery, Mital Pandya

Graduate College Dissertations and Theses

The goal of the work presented herein was to further our understanding of Bovine Leukocyte Antigen (BoLA) class I diversity of Holstein cattle and develop tools to measure class I restricted T cell responses to intracellular pathogens such as foot and mouth disease virus (FMDV) following vaccination. BoLA is a highly polymorphic gene region that allows the bovine immune system to differentiate pathogen-infected cells from healthy cells. Immune surveillance by CD8+ T cells plays an important role in clearing viral infections. These CD8+ T cells recognize BoLA class I molecules bearing epitopes (antigenic peptides) of intracellular origin in their peptide …