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Lasso Based State Transition Modeling With Interactions In Adaptive Interdisciplinary Pain Management, Amith Viswanatha Aug 2022

Lasso Based State Transition Modeling With Interactions In Adaptive Interdisciplinary Pain Management, Amith Viswanatha

Industrial, Manufacturing, and Systems Engineering Dissertations

The Eugene McDermott Center for Pain Management at the University of Texas Southwestern Medical Center has an interdisciplinary pain management program for chronic pain. This program treats patients with a holistic view of reducing chronic pain and improving their physical, mental, and social well-being through treatment interventions. The development of an adaptive treatment decision tool is main goal of the research project. This program is modeled as a two-stage adaptive treatment decision problem, with state transition models representing the transition of patient state, treatment, and outcome variables from stage 1 to stage 2. Interactions between the patient state and treatments …


Machine Learning Framework For Nonlinear And Interaction Relationships Involving Categorical And Numerical Features, Shirish Mohan Rao Aug 2021

Machine Learning Framework For Nonlinear And Interaction Relationships Involving Categorical And Numerical Features, Shirish Mohan Rao

Industrial, Manufacturing, and Systems Engineering Dissertations

Traditionally, physical scientific experiments have been conducted extensively to study and understand the behavior of a process or a system. With the advancement of computing technology in recent years, computer codes and algorithms are used as simulators to replicate behavior of a complex system. Such use of computers to study a system is termed as ‘computer experiments.’ The process involves selecting specific points or runs in the design space in order to maximize information about the system in minimal runs. These computer models are high dimensional and can take a long time to simulate. Metamodels (or surrogate models) built using …


Interaction Between Primary Resources And Root Causes In Lean Production Systems, Ernest Anene Iwuchukwu May 2011

Interaction Between Primary Resources And Root Causes In Lean Production Systems, Ernest Anene Iwuchukwu

Masters Theses

A model to analyze lean systems reliability is developed based on the premises that lean production systems require four primary resources; materials, equipment, personnel, and schedule (Sawhney, R., Subburaman, K., Sonntag, C., Capizzi, C. and Rao, P.V., 2009). The four primary lean resources were independently analyzed, without due consideration to underlying relationships within each other. In this research, relationships and interaction between root-causes and lean primary resources were conceptualized and developed. The development applied a five-phase approach: 1. review of related literature, 2. decompositions of lean primary resources, 3. selection of consensus root causes items and questionnaire construct, 4. survey …