Operations Research, Systems Engineering and Industrial Engineering Commons^™

Achieving Totally Local Anticoagulation On Blood Contacting Devices, Rana Gbyli, Anna Mercaldi, Harihara Sundaram, Kagya Amoako

Mechanical and Industrial Engineering Faculty Publications

The recent years have witnessed an increased activity in biocompatibility research aimed at limiting biomaterial-induced blood coagulation. From 2008 to 2016, a total of $36,946,764.00 USD was awarded in grants to 213 research proposals and as large as 50.4% ($18,627,854.00) of that award monies were distributed to 101 proposals over the fiscal years of FY14 to FY16 alone. However, the complexity in blood responses to biomaterials, variability in blood function between individuals and animal species, and differences in medical device application and test setting all continue to pose difficulties in making a breakthrough in this field. This review focuses on …

Cyber-Physical System Characterization And Co-Regulation Of A Quadrotor Uas, Seth E. Doebbeling

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

An Unmanned Aircraft System (UAS) is a Cyber-Physical System (CPS) in which a host of real-time computational tasks contending for shared resources must be cooperatively managed to obtain mission objectives. Traditionally, control of the UAS is designed assuming a fixed, high sampling rate in order to maintain reliable performance and margins of stability. But emerging methods challenge this design by dynamically allocating resources to computational tasks, thereby affecting control and mission performance. To apply these emerging strategies, a characterization and understanding of the effects of timing on control and trajectory following performance is required. Going beyond traditional control evaluation techniques, …

An Optimization Model For Operating Room Scheduling To Reduce Blocking Across The Perioperative Process, Amin Abedini, Wei Li, Honghan Ye

Mechanical Engineering Faculty Publications

Operating room (OR) scheduling is important. Because of increasing demand for surgical services, hospitals must provide high quality care more efficiently with limited resources. When constructing the OR schedule, it is necessary to consider the availability of downstream resources, such as intensive care unit (ICU) and post anaesthesia care unit (PACU). The unavailability of downstream resources causes blockings between every two consecutive stages. In this paper we address the master surgical schedule (MSS) problem in order to minimize blockings between two consecutive stages. First, we present a blocking minimization (BM) model for the MSS by using integer programming, based on …

Strategic Level Proton Therapy Patient Admission Planning: A Markov Decision Process Modeling Approach, Shengfan Zhang, Ridvan Gedik, Chase Rainwater

Mechanical and Industrial Engineering Faculty Publications

A relatively new consideration in proton therapy planning is the requirement that the mix of patients treated from different categories satisfy desired mix percentages. Deviations from these percentages and their impacts on operational capabilities are of particular interest to healthcare planners. In this study, we investigate intelligent ways of admitting patients to a proton therapy facility that maximize the total expected number of treatment sessions (fractions) delivered to patients in a planning period with stochastic patient arrivals and penalize the deviation from the patient mix restrictions. We propose a Markov Decision Process (MDP) model that provides very useful insights in …

A Constraint Programming Approach For The Team Orienteering Problem With Time Windows, Ridvan Gedik, Emre Kirac, Ashlea Bennet Milburn, Chase Rainwater

Mechanical and Industrial Engineering Faculty Publications

The team orienteering problem with time windows (TOPTW) is a NP-hard combinatorial optimization problem. It has many real-world applications, for example, routing technicians and disaster relief routing. In the TOPTW, a set of locations is given. For each, the profit, service time and time window are known. A fleet of homogenous vehicles are available for visiting locations and collecting their associated profits. Each vehicle is constrained by a maximum tour duration. The problem is to plan a set of vehicle routes that begin and end at a depot, visit each location no more than once by incorporating time window constraints. …

Mapping And Integrating Value Creation Factors With Life-Cycle Stages For Sustainable Manufacturing, P. Bilge, S. Emec, G. Seliger, Ibrahim S. Jawahir

Institute for Sustainable Manufacturing Faculty Publications

Instead of implementing each element individually, engineers must be aware of multiple interactions among all major value creation factors and their life-cycle stages. Interactions are analyzed by a set of factors and hierarchical levels within a production system based on empirical observations and described in analytical models. Such analyses and missing information about the current condition of the system and its parts remain limited to addressing specific aspects of interactions among factors and stages for multiple decision making. To build a case-based scope addressing the interactions among a set of factors and life-cycle stages, a comprehensive approach for mapping and …

Work Zone Simulator Analysis: Driver Performance And Acceptance Of Missouri Alternate Lane Shift Configurations, Suzanna Long, Ruwen Qin, Dincer Konur, Ming-Chuan Leu, S. Moradpour, S. Thind, H. Nadathur

Engineering Management and Systems Engineering Faculty Research & Creative Works

The objective of this project is to evaluate MoDOT’s alternate lane shift sign configuration for work zones. The single signproposed by MoDOT provides the traveler with enough information to let them know that all lanes are available to shift around thework zone, whereas the MUTCD signs require drivers to see two signs. This research simulation project evaluates the drivers’ laneshifting performance and acceptance of the alternate lane shift sign proposed by MoDOT to be used on work zones as compared tothe MUTCD lane shift signs. Based on the study results, no difference was observed between MUTCD lane shift sign andMoDOT …

Carbon Footprint Stock Analysis Of U.S. Manufacturing: A Time Series Input-Output Lca, Gokhan Egilmez, Khurrum Bhutta, Bulent Erenay, Yong Shin Park, Ridvan Gedik

Mechanical and Industrial Engineering Faculty Publications

The purpose of this paper is to provide an input-output life cycle assessment model to estimate the carbon footprint of US manufacturing sectors. To achieve this, the paper sets out the following objectives: develop a time series carbon footprint estimation model for US manufacturing sectors; analyze the annual and cumulative carbon footprint; analyze and identify the most carbon emitting and carbon intensive manufacturing industries in the last four decades; and analyze the supply chains of US manufacturing industries to help identify the most critical carbon emitting industries.

Condition Assessment Of End-Of-Use Products For Remanufacturing, Jovan Morgan

Research Opportunities for Engineering Undergraduates (ROEU) Program 2016-17

The goal of the project is to use the automated 3-D laser scanner using a Capnut as a test object to detect surface defects, corrosion and calculation error through offline quality inspection. potentially reducing labor time and cost for both consumers and manufacturers.

Modeling Of Selective Laser Sintering/ Selective Laser Melting, Xuan Wang, Connor West

Industrial and Manufacturing Engineering

Selective laser sintering and selective laser melting are powder based additive manufacturing (AM) process that can rapidly manufacture parts with comparable mechanical properties to conventional manufacturing methods directly from digital files. However, the processing recipe development and design optimization of AM parts are often based on trial and error which erodes the benefit of AM. Modeling is a powerful tool to enable faster development cycle by significantly reducing the experimental efforts. In this paper we discussed the current status of selective laser sintering/melting modeling, in which the laser and powder interaction was studied to understand and predict the process and …

Sensitivity Analysis Method To Address User Disparities In The Analytic Hierarchy Process, Marie Ivanco, Gene Hou, Jennifer Michaeli

Mechanical & Aerospace Engineering Faculty Publications

Decision makers often face complex problems, which can seldom be addressed well without the use of structured analytical models. Mathematical models have been developed to streamline and facilitate decision making activities, and among these, the Analytic Hierarchy Process (AHP) constitutes one of the most utilized multi-criteria decision analysis methods. While AHP has been thoroughly researched and applied, the method still shows limitations in terms of addressing user profile disparities. A novel sensitivity analysis method based on local partial derivatives is presented here to address these limitations. This new methodology informs AHP users of which pairwise comparisons most impact the derived …

Survey Of Lean Management Practices In Pakistani Industrial Sectors, Khurrum Bhutta, Gokhan Egilmez, Kamran Chatha, Faizul Huq

Mechanical and Industrial Engineering Faculty Publications

This research was undertaken to study the implementation and adoption of Lean management practices across several industrial sectors in Pakistan. A total of 100 companies were surveyed across five industries. The objective was to determine if there was disparity in the implementation of Lean practices and to provide a yardstick to measure that disparity. Furthermore, this study identified Lean management best practices across several industries in Pakistan, thus providing benchmarks for other industrial sectors. The data collected was analysed using various descriptive statistical methods. The results indicated robust adoption and implementation of Lean practices in Pakistani industry, though there were …

From Green Buildings To Green Supply Chains: An Integrated Input Output Life Cycle Assessment And Optimization Framework For Carbon Footprint Reduction Policy Making, N. Muhammad Aslaam, Gokhan Egilmez, Murat Kucukvar, M.Khurrum S. Butta

Mechanical and Industrial Engineering Faculty Publications

Purpose: This paper focuses on tracing GHG emissions across the supply chain industries associated with the U.S. residential, commercial and industrial building stock and provides optimized GHG reduction policy plans for sustainable development.

Design/Methodology/Approach: A two-step hierarchical approach is developed. Firstly, Economic Input Output-based Life Cycle Assessment (EIO-LCA) is utilized to quantify the GHG emissions associated with the U.S. residential, commercial and industrial building stock. Secondly, a mixed integer linear programming (MILP) based optimization framework is developed to identify the optimal GHG emissions’ reduction (%) for each industry across the supply chain network of the U.S. economy.

Findings: The results …