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Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering
Time And Degree Of Glycemic Derangement Are Associated With Increased Mortality In Trauma Patients In The Setting Of Tight Glycemic Control, Michael G. Corneille, Celina Villa, Steven Wolf, Joel E. Michalek, Inkyung Jung, Charles E. Wade, John G. Meyers, Daniel L. Dent, Deborah Mueller, Ronald M. Stewart
Time And Degree Of Glycemic Derangement Are Associated With Increased Mortality In Trauma Patients In The Setting Of Tight Glycemic Control, Michael G. Corneille, Celina Villa, Steven Wolf, Joel E. Michalek, Inkyung Jung, Charles E. Wade, John G. Meyers, Daniel L. Dent, Deborah Mueller, Ronald M. Stewart
US Army Research
BACKGROUND: Tight glucose control (TGC) may reduce mortality in critically ill trauma patients. We hypothesize that euglycemia is beneficial, and a measure considering time and degree of hyperglycemia is most associated with mortality.
METHODS: We performed a review of intensive care unit trauma patients admitted for more than 3 days between January 2005 and December 2007 on a TGC protocol with a goal of 80 to 110 mg/dL. Hyperglycemic, hypoglycemic, and euglycemic time ranges, and area of interpolated curves above and below 80 to 110 mg/dL were assessed. Associations with mortality were based on logistic regression models adjusted for age, …