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Operations Research, Systems Engineering and Industrial Engineering Commons™
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Articles 1 - 3 of 3
Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering
A Machine Learning Approach For Predicting Clinical Trial Patient Enrollment In Drug Development Portfolio Demand Planning, Ahmed Shoieb
A Machine Learning Approach For Predicting Clinical Trial Patient Enrollment In Drug Development Portfolio Demand Planning, Ahmed Shoieb
Masters Theses
One of the biggest challenges the clinical research industry currently faces is the accurate forecasting of patient enrollment (namely if and when a clinical trial will achieve full enrollment), as the stochastic behavior of enrollment can significantly contribute to delays in the development of new drugs, increases in duration and costs of clinical trials, and the over- or under- estimation of clinical supply. This study proposes a Machine Learning model using a Fully Convolutional Network (FCN) that is trained on a dataset of 100,000 patient enrollment data points including patient age, patient gender, patient disease, investigational product, study phase, blinded …
Optimizing Boat Hull And Deck Mold Storage Scheduling With Linear Programming, Tron Bjorn Dareing
Optimizing Boat Hull And Deck Mold Storage Scheduling With Linear Programming, Tron Bjorn Dareing
Masters Theses
With a wide range of products, Sea Ray uses a vast amount of large boat molds for each of the different boat models. Storing and transporting these molds can be an issue with introducing high variability in the production process. One of the largest problems deals with the utilization of the employees’ time with the large amount of boat production. Having the boat molds being ready for production is a critical part of the manufacturing of quality boats. There is non-value added time spent on preparing the molds for the lamination process and storing them in various areas. This problem …
A Stochastic Model For Self-Scheduling Problem, Lili Zhang
A Stochastic Model For Self-Scheduling Problem, Lili Zhang
Masters Theses
The unit commitment (UC) problem is a typical application of optimization techniques in the power generation and operation. Given a planning horizon, the UC problem is to find an optimal schedule of generating units, including on/off status and production level of each generating unit at each time period, in order to minimize operational costs, subject to a series of technical constraints. Because technical constraints depend on the characteristics of energy systems, the formulations of the UC problem vary with energy systems. The self-scheduling problem is a variant of the UC problem for the power generating companies to maximize their profits …