Optimal Route Planning Using Computer Simulation In The Context Of Distributor-To-Consumer Supply Network, Miriam Aguilera Nava

Open Access Theses & Dissertations

Effective route planning for distribution centers is a multifaceted challenge crucial tobusiness success, as it directly impacts time and cost savings while enhancing overall delivery efficiency. Oversight of proper planning can lead to problems and inefficiencies in the distribution process. Hence, this work undertakes a comparative experiment of two delivery strategies in a distributor-to-consumer supply network. While the first strategy investigates the delivery process by zip area, the second strategy considers the clustering of the areas for more streamlined delivery fulfillment. The effectiveness of the delivery process is gauged based on a set of metrics, including total distance traveled, average …

A Machine Learning Approach For Predicting Clinical Trial Patient Enrollment In Drug Development Portfolio Demand Planning, Ahmed Shoieb

Masters Theses

One of the biggest challenges the clinical research industry currently faces is the accurate forecasting of patient enrollment (namely if and when a clinical trial will achieve full enrollment), as the stochastic behavior of enrollment can significantly contribute to delays in the development of new drugs, increases in duration and costs of clinical trials, and the over- or under- estimation of clinical supply. This study proposes a Machine Learning model using a Fully Convolutional Network (FCN) that is trained on a dataset of 100,000 patient enrollment data points including patient age, patient gender, patient disease, investigational product, study phase, blinded …

Mitigating Supply Chain Disruptions In Retail Discount Department Stores, Anthony T. Patton

Walden Dissertations and Doctoral Studies

Supply chain disruptions can have adverse effects on business outcomes. Retail industry supply chain leaders are concerned with supply chain disruptions because supply chain disruptions can lead to dissatisfied customers and loss of profits. Grounded in game theory, the purpose of this multiple case study was to explore strategies four retail industry supply chain leaders in Northern Illinois and Northwest Indiana implemented to mitigate the effects of supply chain disruptions. Data were collected using semistructured virtual interviews with four retail industry supply chain leaders and a review of company documents. Through thematic analysis, four themes emerged: (a) choosing appropriate inventory …

Strategies Aircraft Manufacturing Organizational Leaders Use For Proper Material Pricing, Chin Kuei Jen

Walden Dissertations and Doctoral Studies

The lack of proper material pricing strategies can challenge manufacturers’ profitability and growth. Aircraft manufacturing leaders are concerned because understanding and developing material pricing strategies are essential to increasing profitability. Grounded in price theory, the purpose of this qualitative single case study was to explore strategies aircraft manufacturing organizational leaders use for proper material pricing estimates. The participants were four aircraft manufacturing organizational leaders from a successful aircraft manufacturing business located in the state of Georgia. Data were gathered from semistructured interviews and document reviews and analyzed using Yin’s five step approach. The four themes that emerged were the impact …

Strategies Aircraft Manufacturing Organizational Leaders Use For Proper Material Pricing, Chin Kuei Jen

Walden Dissertations and Doctoral Studies

The lack of proper material pricing strategies can challenge manufacturers’ profitability and growth. Aircraft manufacturing leaders are concerned because understanding and developing material pricing strategies are essential to increasing profitability. Grounded in price theory, the purpose of this qualitative single case study was to explore strategies aircraft manufacturing organizational leaders use for proper material pricing estimates. The participants were four aircraft manufacturing organizational leaders from a successful aircraft manufacturing business located in the state of Georgia. Data were gathered from semistructured interviews and document reviews and analyzed using Yin’s five step approach. The four themes that emerged were the impact …

Analyzing The Supply Chain Operation Of A Fast-Food Restaurant Using Simulation Modeling And Developing A Cost Estimation Optimization Model In The Disruption Period, Amit Kumar Saha

Open Access Theses & Dissertations

Supply chain operation performance is a much-discussed topic over the last decade which will lead to optimizing the resources required to provide the necessary level of customer service to a specific segment and improve customer service through increased product availability and reduced order cycle time. During disruption in supply chain, performance parameter changes, and the overall supply chain cost at each stage increases. External factors such as labor shortages, delayed and costly supplies, and decreased demand also contribute to this cost. This thesis work presents a research-focused analysis of a small pizza shop, under circumstances that include the loss of …

Optimal Global Supply Chain And Warehouse Planning Under Uncertainty, Avnish Kishor Malde

All Dissertations

A manufacturing company's inbound supply chain consists of various processes such as procurement, consolidation, and warehousing. Each of these processes is the focus of a different chapter in this dissertation.

The manufacturer depends on its suppliers to provide the raw materials and parts required to manufacture a finished product. These suppliers can be located locally or overseas with respect to the manufacturer's geographic location. The ordering and transportation lead times are shorter if the supplier is located locally. Just In Time (JIT) or Just In Sequence (JIS) inventory management methods could be practiced by the manufacturer to procure the raw …

Supply Chain Optimization Of A Local Small Business From The Food-Service Industry Using Simulation Models, Aimee Montalvo

Open Access Theses & Dissertations

Various supply chain disruptions can cause revenue losses, low productivity, and damaged reputations. Some examples of such disruptions include increased supply costs, labor shortages, pandemics, natural disasters, or transportation delays. For instance, during the COVID-19 pandemic, several small and medium enterprises (SMEs) suffered greatly from labor shortages, delayed and costly supplies, and decreased demand. In this research, we present a case study of a small local business from the fast-food industry that experienced the loss of employees and delays and analyzed the increased cost of supplies. We created visualization modules with the SMEs supply chain performance measures to see the …

Analyzing The Critical Supply Chain For Unmanned Aircraft Systems, Megan L. Muniz

Theses and Dissertations

Unmanned aerial systems (UAS) play a vital role in present day operations due their asset capability and ability to reduce risk to pilots’ lives. A complex supply chain network capable of producing and integrating all raw materials, components, sub- systems, and systems supports the successful acquisition of a UAS. Such a complex network is supported by vital supply chain decisions. Two important decisions regarding supply chain design include supplier selection and optimal flow of material and product Whether a decision maker wishes to design or interdict a supply chain, the methodology developed in this thesis provides a suite of tailorable …

Multi-Level Analytic Network Process Model To Mitigate Supply Chain Disruptions In Disaster Recovery Planning, Martina Ursula Kroener

Master's Theses

Over the past few decades, environmental changes have led to more frequent occurrences and greater intensities of natural disasters worldwide. In terms of globally connected supply chains, this has resulted in an enormous economical loss for corporations. Therefore, Business Continuity and Disaster Recovery (BC/DR) planning and management has become essential for businesses in order to protect their critical business flow. Yet there is a lack of systematic and transparent methodologies for companies to handle this problem.

Hence, this thesis introduces a novel approach to combine consecutive steps of the Disaster Recovery Planning (DRP) process within one application. The multi-criteria decision-making …

A Simulation Model For Decision Support In Business Continuity Planning, Marissa Anne Mosunich

Master's Theses

Enterprises with a global supply network are at risk of lost revenue as a result of disruptive disasters at supplier locations. Various strategies exist for addressing this risk, and a variety of types of research has been done regarding the identification, assessment and response to the risk of disruption in a supply chain network.

This thesis establishes a decision model to support Business Continuity Planning at the first-tier supplier level. The decision model incorporates discrete-event simulation of supply chain networks (through Simio software), Monte Carlo simulation, and risk index optimization. After modeling disruption vulnerability in a supply chain network, costs …

An Automated Solution For Analyzing Supply Chain Performance, Paul Ringelstein

Industrial and Manufacturing Engineering

The world is becoming increasingly connected as technology progresses and globalization reaches more countries. This interconnection creates new challenges and new relationships for both people and businesses. Now, more than ever, businesses have to work together to satisfy the high demands of customers.In a world full of complex organizations that do business together, the supply chain has become the heartbeat of corporations. The interconnectedness of the organizations in the supply chain is critical to the success of all components of the supply chain. In order to gain an advantage in markets today, data needs to be used to determine where …

Designing A Supply Chain For Wine Imports, Italy To California, Neil Magnuson, Sam Bucher

Industrial and Manufacturing Engineering

Executive Summary

In this report a framework for a hypothetical business will be covered. Bucher & Magnuson Wine Import Inc. has provided a business plan as well as a detailed supply chain design for operations. In addition, a model for scaling and a redesign of a possible storage facility will be found. This comprehensive document outlines end to end the supply chain model of the hypothetical business and moreover a framework for starting a wine import business in San Luis Obispo.

The conclusions of the results from this model are the following:

• Unconcerned with time, the cheapest route for 1 …

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Modeling Supply Chain Interdependent Critical Infrastructure Systems, Varun Ramachandran

Doctoral Dissertations

"While strategies for emergency response to large-scale disasters have been extensively studied, little has been done to map medium- to long-term strategies capable of restoring supply chain infrastructure systems and reconnecting such systems from a local urban area to national supply chain systems. This is, in part, because no comprehensive, data-driven model of supply chain networks exists. Without such models communities cannot re-establish the level of connectivity required for timely restoration of goods and services. This dissertation builds a model of supply chain interdependent critical infrastructure (SCICI) as a complex adaptive systems problem. It defines model elements, data needs/element, the …

Modeling Sustainability In Renewable Energy Supply Chain Systems, Fei Xie

All Dissertations

This dissertation aims at modeling sustainability of renewable fuel supply chain systems against emerging challenges. In particular, the dissertation focuses on the biofuel supply chain system design, and manages to develop advanced modeling framework and corresponding solution methods in tackling challenges in sustaining biofuel supply chain systems. These challenges include: (1) to integrate 'environmental thinking' into the long-term biofuel supply chain planning; (2) to adopt multimodal transportation to mitigate seasonality in biofuel supply chain operations; (3) to provide strategies in hedging against uncertainty from conversion technology; and (4) to develop methodologies in long-term sequential planning of the biofuel supply chain …

Large-Scale Solution Approaches For Healthcare And Supply Chain Scheduling, Ridvan Gedik

Graduate Theses and Dissertations

This research proposes novel solution techniques for two real world problems. We first consider a patient scheduling problem in a proton therapy facility with deterministic patient arrivals. In order to assess the impacts of several operational constraints, we propose single and multi-criteria linear programming models. In addition, we ensure that the strategic patient mix restrictions predetermined by the decision makers are also enforced within the planning horizon. We study the mathematical structures of the single criteria model with strict patient mix restrictions and derive analytical equations for the optimal solutions under several operational restrictions. These efforts lead to a set …

Time-Driven Activity-Based Costing For Healthcare Provider Supply Chain Processes, Martha Isaura Gonzalez

Graduate Theses and Dissertations

In a time when healthcare costs continue to rise, nearly a third of hospital operating expenses are related to supplies, and the healthcare supply chain is complex, it is pertinent for healthcare providers to have a clear understanding of their healthcare supply chain process costs. Having a clear picture into how these costs are driven and where opportunities for cost reductions exist can support supply chain efficiencies. In this research, we develop a Time-Driven Activity-Based Costing (TDABC) supply chain cost management tool for healthcare providers. A TDABC management system can provide healthcare providers with valuable product and process supply chain …

A Socio-Technical Analysis Of Widespread Electric Vehicle Adoption, Onanwa Nneka Egbue

Doctoral Dissertations

A combination of high fuel costs, concerns about petroleum availability, and environmental issues associated with conventional vehicles powered by fossil fuels are driving interests in electric vehicles (EVs). Large-scale deployment of EVs can play a significant role in addressing some of these problems. In spite of the benefits of EVs, several obstacles need to be overcome before EVs will be widely adopted. This research focuses on two socio-technical issues that affect widespread adoption and sustainability of EVs, consumer attitudes and perceptions, and supply chain risks of raw materials for EV battery technology. A major barrier is that consumers tend to …

A Practical Approach To Computer Donation Supply Chain For Non-Profit Organizations, John Jacob Burrell, Adam Robert Carpenter

Industrial and Manufacturing Engineering

The United States today has a plethora of unused electronic equipment. This equipment comes from universities, small businesses, corporations, and many other sources. This project looks at the best way to put this equipment back to use for the remainder of its usable life by donating it to non-profit organizations in need. In order to complete this project it was necessary to research the areas of Supply Chain Management, Operations Research, and Engineering Economics. The approach for this specific project first involves analyzing the current donation process at California Polytechnic State University – San Luis Obispo, and its ability to …

A Methodology To Stabilize The Supply Chain, Alfonso Sarmiento

Electronic Theses and Dissertations

In today's world, supply chains are facing market dynamics dominated by strong global competition, high labor costs, shorter product life cycles, and environmental regulations. Supply chains have evolved to keep pace with the rapid growth in these business dynamics, becoming longer and more complex. As a result, supply chains are systems with a great number of network connections among their multiple components. The interactions of the network components with respect to each other and the environment cause these systems to behave in a highly nonlinear dynamic manner. Ripple effects that have a huge, negative impact on the behavior of the …

Design Of A Multi-Echelon Global Supply Chain Network With Microsoftå¨ Excel Premium Solver Plataform, Wilder Ferreira

All Theses

I designed a global supply chain distribution model of one single product, with the objective of minimizing the costs of transportation, handling materials, duties and tariffs, production, and fixed infrastructure. The distribution network has a combination of manufacturing facilities (fixed and to-be-determined), warehouses (to-be-determined), distribution centers (to-be-determined), and customer zones at fixed locations. This network design is similar to the mathematical mixed-integer linear model from Tsiakis, Shah and Pantelides (2001). This model has been implemented in Microsoft Excel, using the Standard Simplex method from Frontline, Inc. This model optimizes the number of facilities worldwide (multi-echelon) along with the flow of …