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Operations Research, Systems Engineering and Industrial Engineering Commons™
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Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering
Nanoparticulate Carriers For Drug Delivery, Samantha Lokelani Crossen, Tarun Goswami
Nanoparticulate Carriers For Drug Delivery, Samantha Lokelani Crossen, Tarun Goswami
Biomedical, Industrial & Human Factors Engineering Faculty Publications
Drug delivery with nanoparticulate carriers is a new and upcoming research area that is making major changes within the pharmaceutical industry. Nanoparticulate carriers are discussed, particularly, engineered nanoparticulate carriers used as drug delivery systems for targeted delivery. Nanoparticulate carriers that are used for drug delivery systems include polymers, micelles, dendrimers, liposomes, ceramics, metals, and various forms of biological materials. The properties of these nanoparticulate carriers are very advantageous for targeted drug delivery and result in efficient drug accumulation at the targeted area of interest, reduced drug toxicity, reduced systemic side effects, and more efficient use of the drug overall. Nanoparticlulate …
Transdermal Drug Delivery Systems: Analysis Of Adhesion Failure, Zachary Brooks, Tushar Goswami, Amy Neidhard-Doll, Tarun Goswami
Transdermal Drug Delivery Systems: Analysis Of Adhesion Failure, Zachary Brooks, Tushar Goswami, Amy Neidhard-Doll, Tarun Goswami
Biomedical, Industrial & Human Factors Engineering Faculty Publications
The most critical component of the TDDS is the adhesive, which is responsible for the safety, efficacy and quality of the patch. For drug delivery to successfully occur, the patch must adhere to the surface of the contact area. If a patch has inadequate adhesion, it is likely to fall off before the entire delivery period has been satisfied, leading to risks for the patient and others who may encounter the patch. Despite the critical concerns associated with the adhesive properties of the patches, the adhesion quality and failure mechanisms have not been fully studied. If certain molecules encounter the …