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Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering

Novel Models And Efficient Algorithms For Network-Based Optimization In Biomedical Applications, Seyed Javad Sajjadi Jun 2014

Novel Models And Efficient Algorithms For Network-Based Optimization In Biomedical Applications, Seyed Javad Sajjadi

USF Tampa Graduate Theses and Dissertations

We introduce and study a novel graph optimization problem to search for multiple cliques with the maximum overall weight, to which we denote as the Maximum Weighted Multiple Clique Problem (MWMCP). This problem arises in research involving network-based data mining, specifically, in bioinformatics where complex diseases, such as various types of cancer and diabetes, are conjectured to be triggered and influenced by a combination of genetic and environmental factors. To integrate potential effects from interplays among underlying candidate factors, we propose a new network-based framework to identify effective biomarkers by searching for "groups" of synergistic risk factors with high predictive …


Operations Research Modeling Of Cyclic Train Timetabling, Cyclic Train Platforming, And Bus Routing Problems, Mojtaba Heydar May 2014

Operations Research Modeling Of Cyclic Train Timetabling, Cyclic Train Platforming, And Bus Routing Problems, Mojtaba Heydar

Theses and Dissertations

Public transportation or mass transit involves the movement of large numbers of people between a given numbers of locations. The services provided by this system can be classified into three groups: (i) short haul: a low-speed service within small areas with high population; (ii) city transit: transporting people within a city; and (iii) long haul: a service with long trips, few stops, and high speed (Khisty and Lall, 2003). It can be also classified based on local and express services. The public transportation planning includes five consecutive steps: (i) the network design and route design; (ii) the setting frequencies or …