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Full-Text Articles in Nuclear Engineering

Temporal Resolution Of Cell Death Signaling Events Induced By Cold Atmospheric Plasma And Electroporation In Human Cancer Cells, Danielle M. Krug, Prasoon K. Diwakar, Ahmed Hassanein Aug 2017

Temporal Resolution Of Cell Death Signaling Events Induced By Cold Atmospheric Plasma And Electroporation In Human Cancer Cells, Danielle M. Krug, Prasoon K. Diwakar, Ahmed Hassanein

The Summer Undergraduate Research Fellowship (SURF) Symposium

Cancer treatment resistance and their invasive and expensive nature is propelling research towards developing alternate approaches to eradicate cancer in patients. Non-thermal, i.e., cold atmospheric plasma (CAP) and electroporation (EP) applied to the surface of cancerous tissue are new methods that are minimally invasive, safe, and selective. These approaches, both independently and synergistically, have been shown to deplete cancer cell populations, but the signaling mechanisms of death and their timelines of action are still widely unknown. To better understand the timeframe of signaling events occurring upon treatment, human cancer cell lines were treated with CAP, EP, and combined CAP with …


Cold Atmospheric Pressure Plasmas For Food Applications, Michael V. Lauria, Russell S. Brayfield Ii, Ronald G. Johnson, Allen L. Garner Aug 2016

Cold Atmospheric Pressure Plasmas For Food Applications, Michael V. Lauria, Russell S. Brayfield Ii, Ronald G. Johnson, Allen L. Garner

The Summer Undergraduate Research Fellowship (SURF) Symposium

Successfully distributing shelf food requires treatment to eliminate microorganisms. Current chemical methods, such as chlorine wash, can alter food quality while only being effective for a limited time. Cold atmospheric pressure plasmas (CAPs) can eradicate the microorganisms responsible for food spoilage and foodborne illness. Optimizing CAP treatments requires understanding the reactive species generated and relating them to eradication efficiency. Recent studies have used optical emission spectroscopy (OES) to determine the species generated in a sealed package that would hold food. In this study,we supplement the OES results with optical absorption spectroscopy (OAS) using the same gases (helium, nitrogen, compressed air, …


Cold Atmospheric Plasma: An Inside Look Through Optical Diagnostics For Biomedical Applications, Liesl Krause, Ahmed Hassanein, Prasoon Diwakar Aug 2015

Cold Atmospheric Plasma: An Inside Look Through Optical Diagnostics For Biomedical Applications, Liesl Krause, Ahmed Hassanein, Prasoon Diwakar

The Summer Undergraduate Research Fellowship (SURF) Symposium

An emerging technology for medical applications is cold atmospheric plasma (CAP). CAP is generated using various gasses in a “pen” to create room temperature plasma and then carry the effluents and species. Success has been shown when cold atmospheric plasma is applied to oncology treatments, accelerated wound healing, pathogen disinfection, and various material-changing effects. However, the mechanisms behind these effects are still speculative. This study uses multiple diagnostic techniques including fast photography, two wavelength emission spectroscopy and optical emission spectroscopy to characterize the plasma properties and eventually further test the plasma’s interaction with biological samples. The plume dynamics are observed …